Macular Degeneration
Concept and Etiology: TheMacularDegenerationdiseasecauseslossinthecenterofthe
fieldofvision.Drymaculardegenerationthecenteroftheretinadeteriorates
(Mayoclinic,2021).Thediseaseaffectstheearstudyshowthatthereisalinkbetweenage
relatedhearinglossandagerelatedwithmaculardegeneration50%hadmildhearing
lossand20%hadmoderatehearingloss(VisionConsulants,2011).Dr.Steenblockstated
thatalargepercentageofpatientwhodonotrespondtostemcelltherapyformacular
degenerationhaveachronicsinusinfection(nose)(healingtheeye,2021).The
complementfactorHvariantsalsoconfersusceptibilitytoinvasiveinfectionwithseveral
bacterialcolonizersofthenasopharyngealmucosathissusceptibilitylocusimplicates
complementderegulationasacommondiseasemechanism(PeiHoetal,2018).Thereisa
connectionwiththeeyeanddigestivesystemastudyonmicefoundthatgutbacteria
couldcauseautoimmuneuveitisinflammationeyecondition(Yoursightmatter,2021).
How does it deviate from the definition of health?
Themaculardegenerationdeviatesfromourhealthywayoflife.Weneedoureyesight
thatisimportantfunctionofthebody.Beingaffectbythisdiseasecancausemajor
problemswithinapersonlifestyleespeciallyiftheydon’thavefamilyorfriendsthatcan
helpassistthemwithdifficultthingsthatpertaintohavingahealthyproductivelife.
Classification: NoAMD: afew(5-15),small<63)ornodrusenwithoutpigmentchanges.
EarlyAMD:Severalsmalldrusen,fewintermediatesized(63-124)drusenandpigmentary
changesinoneorbotheyes.IntermediateAMD:Extensivei.e.,20softor65hardwithout
anysoftintermediate-sizeddrusenonelarge(>125)druse,andgeographicatrophynot
involvingthemaculainoneorbotheyes.AdvancedunilateralAMD:Advanceddryform
i.e.,macula-involvinggeographicatrophyorexudativeformwithchoroidal
neovascularizationinoneeye(Scruggs,2019).
Clinical Manifestations (Symptoms and Signs): Thesymptomsofmaculardegeneration
arevisualdistortions,reducedcentralvisionsinoneorbotheyes,increaseddifficulty
adaptingtolowlevels,suchaswhenenteringadimlylitrestaurant,decreasedintensity
orbrightnessofcolors,difficultyrecognizingfaces.Thesignsofmaculardegenerationare
changesincentralvision,abilitytoseecolorsandfinedetailsbecomesimpaired
(Mayoclinic,2020).
Diagnostic Tests: Thesesaretheteststhatareperformedexaminationofthebackofthe
eye,testfordefectsinthecenterofyourvision,afluoresceinangiography,Indocyanine
greenangiography,Opticalcoherencetomography(Mayoclinic,2021).
Mayoclinic(2021,May8).Drymaculardegeneration.
https://www.mayoclinic.org/diseases-condition/dry-macular-degeneration/symptoms-
causes/syc-20350375
NorthSuburban(2011March20).Vision Consultants. AssociationbetweenMacular
DegenerationVisionLoss.https://www.nsvc.com/easyblog/Association-between-
macular-degeneration-vision-loss-and-hearing-loss-found.html#
Healingtheeye(2021).Istherearelationshipbetweensinusdiseaseandmacular
degeneration?https://www
.Healingtheeye.com/Articles/sinus-disease.html
PeiHo,E.X.,etal(2018).HumanPharyngealMicrobiotainage-relatedmacular
degeneration.13(8),e0201768https://doi.org10.1371/journal.pone0201768
YourSightMatter(2021).EyeDiseaseCouldbeCausedbyGutBacteria.
https://www.yoursightmatters.com
Scruggs,B.A.,Avdic,A.,&Gehrs,K.,(2019)Age-relatedmaculardegeneration.Eye
Rounds.
https://www.webeye.ophth.uiowa.edu/eyeforum/atlas/pages/AMD.htm