10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
1/19
Score for this attempt: 78 out of 80
Submitted Oct 4 at 1am
This attempt took 57 minutes.
2 / 2 pts
Question 1
Conversion of VLDL into LDL is associated with what changes?
depletion of cholesteryl-esters
enrichment of the apolipoprotein ApoB-100
Correct!
Correct!
an increase in particle diameter
a decrease in the protein:lipid ratio
ApoE-mediated receptor interactions
2 / 2 pts
Question 2
Which vitamin is NOT fat soluble?
A
C
Correct!
Correct!
D
E
K
2 / 2 pts
Question 3
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
2/19
Waxes are BEST described as:
esters of glycerol and three fatty acids.
esters of one long-chain fatty acid and one long-chain alcohol.
Correct!
Correct!
polyunsaturated long-chain fatty acids.
esters of two long-chain fatty acids.
ethers of glycerol and short-chain alcohols.
2 / 2 pts
Question 4
Fatty acids are attached to sphingosine by what type of chemical linkage?
an ether linkage
an amide linkage
Correct!
Correct!
an ester linkage
a peroxide linkage
a alkyl linkage
2 / 2 pts
Question 5
Human adipocytes contain which enzyme that catalyzes the breakdown
of triacylglycerols?
glycerase
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
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lipase
Correct!
Correct!
fatase
esterase
triacylase
2 / 2 pts
Question 6
Which types of signaling lipids are produced by platelets to aid in the
formation of blood clots?
prostaglandins
thromboxanes
Correct!
Correct!
arachidonates
lipoxins
leukotrienes
2 / 2 pts
Question 7
Which health effect is NOT associated with consumption of trans fats?
lowering of HDL cholesterol
increased inflammatory response in the body
raising of LDL cholesterol
increased joint flexibility due to additional membrane fluidity
Correct!
Correct!
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
4/19
increased risk of heart disease
2 / 2 pts
Question 8
Overproduction of which types of signaling lipids causes asthmatic
attacks?
prostaglandins
thromboxanes
arachidonates
lipoxins
leukotrienes
Correct!
Correct!
2 / 2 pts
Question 9
What cofactor is required for acetyl-CoA carboxylase activity?
NADPH
thiamine pyrophosphate
lipoamide
Correct!
Correct!
biotin
both thiamine pyrophosphate and lipoamide
2 / 2 pts
Question 10
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
5/19
Which feature allows certain lipid molecules to be used as colorful
pigments in plants and animals?
Their high oxygen content helps electrons circulate, which
allows absorption of visible light.
Their conjugated bond structures allow absorption of visible
light.
Correct!
Correct!
Their four-fused ring structure allows visible light reflection.
Their hydrophobicity bends light around them.
Their low specific gravities cause light to reflect from their
surfaces.
2 / 2 pts
Question 11
Which statement is NOT true of the fatty acid elongation system of
vertebrate cells?
It involves the same four-step sequence seen in the fatty acid
synthase complex.
It is located in the smooth endoplasmic reticulum.
It produces stearoyl-CoA by the extension of palmitoyl-CoA.
It uses malonyl-CoA as a substrate.
The immediate precursor of the added carbons is acetyl-CoA.
Correct!
Correct!
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
6/19
2 / 2 pts
Question 12
Which statement about sterols is TRUE?
All sterols share a fused-ring structure with four rings.
Correct!
Correct!
Sterols are found in the membranes of all living cells.
Sterols are soluble in water, but less so in organic solvents such
as chloroform.
Cholesterol is the principal sterol in fungi.
The principal sterol of animal cells is ergosterol.
2 / 2 pts
Question 13
Which term BEST describes the cholesterol molecule?
amphipathic
Correct!
Correct!
nonpolar, charged
nonpolar, uncharged
polar, charged
polar, uncharged
2 / 2 pts
Question 14
Which compound can be cleaved in half to generate a molecule important
in vision?
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
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calcitol
beta-carotene
Correct!
Correct!
arachidonic acid
tocopherol
isoprene
2 / 2 pts
Question 15
What feature do Tay-Sachs disease, Fabry disease, and Niemann-Pick
disease have in common?
defects in enzymes responsible for synthesizing membrane
lipids
defects in enzymes responsible for breaking down membrane
lipids in the lysosomes
Correct!
Correct!
hyperactive membrane lipid degradation enzymes
defects in enzymes responsible for cholesterol synthesis
All of the answers are correct.
2 / 2 pts
Question 16
Synthesis of malonyl-CoA from acetyl-CoA is MOST similar to what
other reaction?
converion of malate into fumarate
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
8/19
conversion of pyruvate into acetyl-CoA
conversion of phosphoenolpyruvate into 2-phosphoglycerate
conversion of glutamate into -ketoglutarate
conversion of pyruvate into oxaloacetate
Correct!
Correct!
2 / 2 pts
Question 17
What is the source of the polar headgroup in the formation of
sphingomyelin?
CDP-choline
phosphocholine
cardiolipin
phosphoserine
phosphatidylcholine
Correct!
Correct!
2 / 2 pts
Question 18
In the synthesis of phosphatidylcholine from phosphatidylethanolamine,
the methyl group donor is:
a tetrahydrofolate derivative.
choline.
methanol.
S-adenosylmethionine (adoMet).
Correct!
Correct!
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
9/19
serine.
2 / 2 pts
Question 19
In E. coli the synthesis of phosphatidylethanolamine directly involves:
acyl carrier protein.
biotin.
CDP-choline.
phosphatidylglycerol.
serine.
Correct!
Correct!
2 / 2 pts
Question 20
Which technique is NOT commonly used to analyze lipid composition?
selective extraction using apolar solvents
adsorption chromatography
x-ray crystallography
Correct!
Correct!
hydrolysis using enzymes with specificity for certain linkages
mass spectroscopy
2 / 2 pts
Question 21
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
10/19
Which method can be used to visualize lipids that have been separated by
thin-layer chromatography by reversibly reacting with double bonds in
fatty acids?
ethanol
iodine fumes
Correct!
Correct!
low-wavelength UV light
rhodamine
ethidium bromide
2 / 2 pts
Question 22
Advantages to using triacylglycerols, rather than polysaccharaides, to
store energy include which reason(s)?
The carbon atoms of triacylglycerols are more reduced.
Triacylglycerols contain more oxygen than polysaccharides and
therefore are more efficient to oxidize.
Since triacylglycerols are hydrophobic, excess water does not
need to be stored along with them.
The carbon atoms of triacylglycerols are more reduced, and
since triacylglycerols are hydrophobic, excess water does not
need to be stored along with them.
Correct!
Correct!
Triacylglycerols contain more oxygen than polysaccharides and
therefore are more efficient to oxidize, and since
triacylglycerols are hydrophobic, excess water does not need to
be stored along with them.
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
11/19
2 / 2 pts
Question 23
Which types of membrane lipids make up 70% to 80% of the total
membrane lipids in a vascular plant?
phosphatidylserines
glycosphingolipids
galactolipids
Correct!
Correct!
plasmalogens
sphingomyelins
2 / 2 pts
Question 24
The steroid hormones testosterone and beta-estradiol are derived from
which lipid molecule?
phosphatidylcholine
cholesterol
Correct!
Correct!
lipoxin A
arachidonic acid
geraniol
2 / 2 pts
Question 25
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
12/19
Which lipoproteins do NOT originate from the liver?
chylomicrons and VLDL
VLDL and HDL
LDL and HDL
chylomicrons and HDL
Correct!
Correct!
VLDL and LDL
2 / 2 pts
Question 26
Lipoprotein particles in human blood do NOT contain:
an apolipoprotein B isoform.
cholesterol.
cholesteryl esters.
lecithin.
Correct!
Correct!
triglycerides.
2 / 2 pts
Question 27
_____ contain(s) an ether-linked alkyl group.
Cerebrosides
Gangliosides
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
13/19
Phosphatidyl serine
Platelet-activating factor
Correct!
Correct!
Sphingomyelin
2 / 2 pts
Question 28
Which statement is NOT true of the fatty acid synthase and the fatty acid
-oxidation systems?
A derivative of the vitamin pantothenic acid is involved.
Acyl-CoA derivatives are intermediates.
Double bonds are oxidized or reduced by pyridine nucleotide
coenzymes.
The processes occur in different cellular compartments.
The processes occur in the mitochondrial matrix.
Correct!
Correct!
2 / 2 pts
Question 29
Which statement is TRUE of sphingolipids?
Cerebrosides and gangliosides are sphingolipids.
Correct!
Correct!
Phosphatidylcholine is a typical sphingolipid.
They always contain glycerol and fatty acids.
They contain two esterified fatty acids.
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
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They may be charged, but are never amphipathic.
2 / 2 pts
Question 30
Commercial vegetable oils can be converted from liquid forms to solid
forms and have their shelf lives increased due to which process?
partial desaturation
unsaturation
partial hydrogenation
Correct!
Correct!
hydrolysis
complete esterification
0 / 2 pts
Question 31
Which protein is NOT typically found in HDL?
lecithin cholesterol acyl transferase (LCAT)
ApoE
ApoH
Correct Answer
Correct Answer
ApoC-I
You Answered
You Answered
ApoD
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
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15/19
2 / 2 pts
Question 32
Which statement is TRUE of sphingolipid synthesis?
All of the carbon atoms of palmitate and serine are incorporated
into sphingosine.
CDP-sphingosine is the activated intermediate.
CO is produced during the synthesis of ceramide from
palmitate and serine.
Correct!
Correct!
2
Glucose 6-phosphate is the direct precursor of the glucose in
cerebrosides.
Phosphatidic acid is a key intermediate in the pathway.
2 / 2 pts
Question 33
A 30-carbon precursor of the steroid nucleus is:
farnesyl pyrophosphate.
geranyl pyrophosphate.
isopentenyl pyrophosphate.
lysolecithin.
squalene.
Correct!
Correct!
2 / 2 pts
Question 34
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
16/19
Nonsteroidal antiinflammatory drugs (NSAIDs) inhibit the synthesis of
which signaling lipids from arachidonic acid?
prostaglandins
thromboxanes
leukotrienes
both prostaglandins and thromboxanes
Correct!
Correct!
both thromboxanes and leukotrienes
2 / 2 pts
Question 35
Which statement is FALSE concerning acetyl-CoA carboxylase?
It catalyzes the rate-limiting step in fatty acid synthesis.
This enzyme is inhibited by palmitate in mammals.
This enzyme is allosterically activated by citrate in mammals.
In mammals, this enzyme is inactivated under conditions when
glycolysis is active.
Correct!
Correct!
This enzyme is classified as a ligase.
2 / 2 pts
Question 36
Which type of chemical linkage is used to join fatty acids to glycerol?
an ether linkage
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
https://canvas.liberty.edu/courses/318794/quizzes/1674749
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a peptide bond
an ester linkage
Correct!
Correct!
a double bond
a peroxide bond
2 / 2 pts
Question 37
Tay-Sachs disease is the result of a genetic defect in the metabolism of:
gangliosides.
Correct!
Correct!
phosphatidyl ethanolamine.
sterols.
triacylglycerols.
vitamin D.
2 / 2 pts
Question 38
Which statement about the regulation of cholesterol synthesis is NOT
true?
Cholesterol acquired in the diet has essentially no effect on the
synthesis of cholesterol in the liver.
Correct!
Correct!
Failure to regulate cholesterol synthesis predisposes humans to
atherosclerosis.
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
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18/19
High intracellular cholesterol stimulates formation of
cholesteryl esters.
Insulin stimulates HMG-CoA reductase.
Some metabolite or derivative of cholesterol inhibits HMG-
CoA reductase.
2 / 2 pts
Question 39
Which molecules or substances contain, or are derived from, fatty acids?
beeswax
prostaglandins
sphingolipids
triacylglycerols
All of these contain or are derived from fatty acids.
Correct!
Correct!
2 / 2 pts
Question 40
Which statement about triacylglycerol synthesis is CORRECT?
Humans can store more energy in glycogen than in
triacylglycerols.
Insulin stimulates conversion of dietary carbohydrate into
triacylglycerols.
Correct!
Correct!
10/4/22, 1:01 AM
Quiz: Basic Principles of Lipids: NUTR641: Nutritional Biochemistry I (B01)
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It is not a hormone-sensitive process.
Mammals are unable to convert carbohydrates into
triacylglycerols.
Phosphatidate is not on the pathway of triacylglycerol synthesis.
Quiz Score: 78 out of 80
