Chapter Twenty-Three
Arthritis
Definition
Arthritis is a generic term for conditions that involve inflammation of one or more joints.
There are more than 100 different forms of arthritis, each characterized by varying
degrees of joint damage, restriction of movement, functional limitation, and pain
Pathophysiology
Osteoarthritis
oDegradation of joints
oAffects articular cartilage and subchondral bone
oResults in host of processes leading to joint space narrowing, loss of cartilage,
bone-on-bone rubbing, ligament strain/weakening
oHands, feet, spine, hips, and shoulders most often affected
oSome genetic link, but also affected by injury and obesity
Rheumatoid
oMore likely in females
oResult of chronic autoimmune disorder
Systemic inflammation
oTypically affects synovial joints
Hand and feet most often.
Common negative effects of most types of arthritis
oExercise tolerance
oMuscle strength
oAerobic capacity
oRange of movement
oBiomechanical efficiency
oProprioception
Stages of arthritis
oAcute: reversible signs and symptoms in the joint related to synovitis
oChronic: stable but irreversible structural damage brought on by the disease
process
oChronic with acute exacerbation of joint symptoms: increased pain and
decreased ROM and physical function
Type of arthritis Disease Stage Related impairments
Osteoarthritis Acute joint pain Often insidious
Chronic radiographic joint
disease
Chronic with exacerbation Increase joint pain and
swelling, muscle weakness,
and progressively declining
functional impairment
Rheumatoid arthritis Acute disease in multiple
joints with pain, limited range
of motion, and worsened
functional impairment
Joint stiffness, adverse body
composition changes
(rheumatoid cachexia; muscle
loss and fat gain), muscle
weakness, fatigue, and
increased cardiovascular
disease risk
Ankylosing spondylitis Acute spinal pain and
stiffness without significant
decrease in mobility
Muscle loss, muscle
weakness, and fatigue
Chronic spinal ankyloses
predominant with decreased
spinal and thoracic mobility
Chronic with exacerbation Increased pain and stiffness
of the back or peripheral
joints
Table 23.1 Types of arthritis, stages, and related impairments
Clinical Considerations
Signs and Symptoms
oJoint
Pain
Stiffness
Effusion
Synovitis
Deformity
Crepitus
oHistory and physical exam
General assessment of joint range of motion, alignment, and function
Assess symptoms and family history (genetic component for arthritis)
Assess for extra-articular features specific to types of arthritis to aid
diagnosis
Cardinal signs:
Redness
Swelling
Pain
Heat
oDiagnostic Testing
There are no definitive tests or markers for arthritis diagnosis
Some serum and synovial fluid tests can assist in arthritis type
differentiation
See able 23.2 on distinguishing characteristics and American college of
rheumatology (ACR) diagnostic criteria for arthritis
Exercise Testing
Cardiovascular testing may be needed in patients who are at risk of CVD:
oThose with RA are at increased risk due to the associated systemic inflammation
oThose who are sedentary for extended periods and have other risk factors may
also be at risk
Musculoskeletal and range of motion testing can be performed to provide a baseline for
changes and to help guide the exercise prescription
See table 23.4 on strength, range of motion, and balance testing in arthritis
Treatment
Goals:
oReduce disability
oRestore physical activity
oImprove body composition
oControl symptoms and reduce pain
Treatment focus is now on movement versus previously on rest:
o69% of those with RA are inactive
Nonpharmacologic:
oEducation
oPhysical and occupational therapy
oBraces and bandages
oCanes and other walking aids
oShoe modification and orthotics
oIce and heat modalities
oWeight reduction
oAvoidance of repetitive-motion occupations
oJoint irrigation and joint surgery (in select circumstances).
Pharmacologic
oDisease-modifying antirheumatic drugs ( DMARDs)
oSee table 23.5 Pharmacology
Exercise Prescription
Goals:
oMaintain or improve physical function by maintaining or improving muscle
strength, cardiovascular fitness, and ROM
oImprove body composition (i.e., restore muscle mass and reduce fat mass), and
when appropriate, reduce body weight.
oReduce the risk of comorbidities such as CVD and osteoporosis
oReduce inflammation and pain
oPrevent contractures and deformities
See table 23.6 for arthritis site-specific recommendations
See table 23.7 for athritis stages, general signs and symptoms, and exercise prescription
See table 23.8 for exercise prescription review
Important considerations
oPreventing musculoskeletal injury
oFatigue
oPrevious joint replacement
oTime of day
oWater therapy
oFootwear
oCV and pulmonary issues with RA
oAnkylosing spondylitis (arthritis of the spine leading to vertebral fusing)
oCorticosteroids
oBody composition
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