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5-4 Project Part One: Planning Document Second Draft
Jasmine (Jay) Peters
Southern New Hampshire University
SCI-200: Applied Natural Sciences
Jane Pablico
June 11, 2024
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5-4 Project Part One: Planning Document Second Draft
Genetic engineering is the topic I've chosen to explore in the natural sciences. I chose this
topic out of curiosity about the benefits of employing genetic engineering. Genetic engineering
holds great importance, as it plays a crucial role in the development of genetically modified
organisms that can bring immense benefits to humans. These remarkable advancements in
genetic engineering could potentially eradicate numerous terminal illnesses.
Gene therapy is a type of genetic engineering. Through gene therapy, the field of
medicine has discovered a means to rectify genetic abnormalities and potentially treat or
eradicate genetic disorders. Having witnessed several family members succumb to various types
of cancer, this subject immediately grabbed my interest.0
In the past two years, we have experienced a devastating pandemic that claimed countless
lives as a result of COVID-19. We are currently facing the ongoing challenge of COVID-19, and
there has been an increase in cases of the respiratory syncytial virus. Imagine eradicating viruses
and numerous other diseases. Imagine the possibilities if scientists had the ability to enhance the
human gene pool. There are numerous possibilities to consider. I intend to delve further into this
subject and provide answers to some inquiries.
My research question:
What are the long-term effects of genetic engineering on our society? What are the advantages
and disadvantages of genetic engineering?
Here are some of my science resources:
The title of my first source is "Gene Therapy for Regenerative Medicine."
I selected this source because it provides valuable insights into the concept of gene
therapy, its potential benefits for individuals, and its overall impact. The article provides
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insights into the potential of gene therapy in the medical field, authored by scientists
specializing in medical and drug research.
"Hemophagocytic lymph histiocytosis following gene replacement therapy in a child with
type 1 spinal muscular therapy" is the title of my second source.
I selected this source because it highlights the application of gene therapy to improving
quality of life. This source provides information on the application of gene therapy in
pediatric treatment, highlighting certain areas that require further refinement. Given that
the article underwent a rigorous peer review process, and the study took place at a
reputable hospital, this source is highly credible.
I found an interesting source titled "Prime Editing for Human Gene Therapy: Where Are
We Now?"
I chose this source because it provides a clear and accessible explanation of gene therapy
and its potential future benefits for individuals. Renowned doctors have conducted tests
and written papers on the subject.
About my target audience and message:!
I would be delighted to share my findings on genetic engineering with the attendees of a
medical seminar. This audience would be intrigued by the latest advancements in the medical
field, possibly unaware of the previous studies conducted on the subject. Given the audience of
medical students and professionals, it would be appropriate to incorporate medical terminology
into the presentation. However, it is important to ensure that the content remains accessible and
understandable to all, including those who may not be familiar with all the terms. Instead of
delving into the specifics of the pre-research procedures, it may be more beneficial to focus on
the research itself, its findings, and the individuals impacted by it.
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Identifying the principles:!
Based on my research, I have identified chemistry and biology as the natural sciences.
My gene modification topic closely connects to these sciences, as altering DNA involves
modifying the genetic material that defines our identity. They play a crucial role in addressing
my question of morality as they shape our identity as a species. Are these principles sufficient to
ensure gene manipulation's safety in the treatment of incurable and devastating diseases? I have a
serious medical condition that impacts my nervous system. If I had the opportunity to change the
course of my life, would it radically change who I am? Is it ethical to allow parents to create an
ideal child in today's world? This topic is currently receiving a lot of attention due to the recent
Supreme Court decision overturning Wade. Where do we, as humans, define the boundary
between manipulation and termination?
The process involves transferring genetic material to other cells of a patient in order to
combat or eradicate a disease. We are using genetic knowledge to help individuals who suffer
from inherited genetic conditions. We take into account the genetic characteristics we wish for
our offspring.
Principles explained
Understanding the process of gene transfer to combat or eradicate diseases is highly
relevant to my concern, as it has the potential to revolutionize the world by alleviating the
suffering caused by ailments such as cancer. It is evident that further research and testing are
necessary in order to expand the reach of testing worldwide and provide comprehensive
assistance to people.
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Experimental question and hypothesis
When considering the long-term impact of genetic engineering on society, a biologist
would likely direct their investigation towards the ethical implications of this practice. They
would ask if the conduct of genetic engineering conforms to moral standards. From a scientific
standpoint, we hypothesize that educating people about genetic engineering could potentially
change their understanding of its ethical implications.
Conclusion
In order to assess the ethical implications of genetic engineering, scientists specializing in
the natural sciences must first educate the public about the nature of genetic engineering.
Understanding the concept of genetic engineering involves presenting ethical experiments,
discussing its potential beneficiaries, and considering the associated costs. After presenting the
information, ask the group a series of thought-provoking questions to understand their
perspective on the ethical implications of genetic engineering. If the group holds the belief that
genetic engineering is ethical, it could serve as a persuasive strategy to prove that genetic
engineering is indeed ethically feasible.
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References
Galletta, F., Cucinotta, U., Marseglia, L., Cacciola, A., Gallizzi, R., Cuzzocrea, S., Messina,
S., Toscano, A., & Gitto, E. (2022). Hemophagocytic lymphohistiocytosis following
gene replacement therapy in a child with type 1 spinal muscular atrophy. Journal of
Clinical Pharmacy & Therapeutics, 47(9), 1478–1481. https://doi-
org.ezproxy.snhu.edu/10.1111/jcpt.13733
Godbout, K., & Tremblay, J. P. (2023). Prime Editing for Human Gene Therapy: Where Are
We Now? Cells (2073-4409), 12(4), 536.
https://doi-org.ezproxy.snhu.edu/10.3390/cells12040536
Hosseinkhani, H., Domb, A. J., Sharifzadeh, G., & Nahum, V. (2023). Gene Therapy
for Regenerative Medicine. Pharmaceutics, 15(3), 856. https://doi-
org.ezproxy.snhu.edu/10.3390/pharmaceutics15030856
