Malaria POWER POINT
Meral2013
news_presentation_example_1_teixobactin.pptxAn Antibiotic Resistant to
resistance
Biology 1407 presentation
Summer 16
Student
TEIXOBACTIN
teixobactin is the first antibiotic to which resistance by
mutations of pathogens have not been identified.
researchers at Northeastern University discovered it when they
were working to develop a novel method for growing uncultured
bacteria.
what is TEixobactin?
How did they find it?
Dr. Kim Lewis and Dr. Slava Epstein founded NovoBiotic Pharmaceuticals in 2003, where they use an approach based on the iChip, a miniature device Epstein's team created that can isolate and help grow single cells in their natural environment.
In 2015, the team discovered the teixobactin compound on a routine material screening.
What is the significance?
Dr. Kim Lewis and Dr. Slava Epstein, professors at Northeastern University, believe it “presents a promising new opportunity” for treating infections such as staphylococcus aureus, including MRSA, and tuberculosis which are a few of the well-known antibiotic-resistant diseases.
Dr. gerard Wright, McMaster University
just because materials resistance against teixobactin have not been found does not mean they do not exist somewhere in the environment.
However, this discovery could provide insight into "other 'resistance-light' antibiotics.”
he believes the NU team’s "work offers hope that innovation and creativity can combine to solve the antibiotics crisis.”
Skepticism
References
Northeastern University. "Newly discovered antibiotic kills pathogens without resistance." ScienceDaily. ScienceDaily, 8 January 2015. <www.sciencedaily.com/releases/2015/01/150108124854.htm>.
Losee L. Ling, Tanja Schneider, Aaron J. Peoples, Amy L. Spoering, Ina Engels, Brian P. Conlon, Anna Mueller, Till F. Schäberle, Dallas E. Hughes, Slava Epstein, Michael Jones, Linos Lazarides, Victoria A. Steadman, Douglas R. Cohen, Cintia R. Felix, K. Ashley Fetterman, William P. Millett, Anthony G. Nitti, Ashley M. Zullo, Chao Chen, Kim Lewis. A new antibiotic kills pathogens without detectable resistance. Nature, 2015; DOI: 10.1038/nature14098
