Chem Assignment

Number of pages: 1 (275 words) Academic Level: Postgraduate Deadline: 2 hours

Instructions:  Discuss the function in detail of each of the following RNA polymerase II transcription factors. (8 points, 2 points each)  TFIIB  TFIIE  TFIIF  TFIIH  What additional role does one of the subunits of TFIIH have during the initiation phase that involves other protein kinases? What is the end result? (2 points)  Discuss in detail how the 5’ cap is formed in eukarytotic mRNAs. (4 points)  What makes the 3’ end of eukaryotic mRNAs unique? Describe how this is added. (3 points)  What are the five snRNAs involved in splicing reaction, and describe briefly how they work to assemble spliceosomes. (3 points)