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Experiment 5: The Importance of Cell Cycle Control

Data and Post-Lab Questions

Data:

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Post-Lab Questions

1. Record your hypothesis from Step 1 in the Procedure section here.

2. What do your results indicate about cell cycle control?

3. Suppose a person developed a mutation in a somatic cell which diminishes the performance of the body’s natural cell cycle control proteins. This mutation resulted in cancer yet, but was effectively treated with a cocktail of cancer fighting techniques. Is it possible for this person’s future children to inherit this cancer causing mutation? Be specific when you explain why or why not.

4. Why do cells which lack cell cycle control exhibit karyotypes which look physically different than cells with normal cell cycle.

5. What are HeLa cells? Why are HeLa cells appropriate for this experiment?

6. Research the function of the protein called p53. What does this function do? Explain how it can affect cell cycle control.

7. What is the Philadelphia chromosome? How is this chromosome related to cancer? Identify how this chromosome appears physically different on a karyotype than it appears on a karyotype of normal chromosomes.