SPSS LAP assignment
LAB 6:
Contingency Table Analysis
(Chi-Square Analysis)
1
Be able to correctly use and interpret Pearson Chi-Square test, a test for independence between two qualitative variables.
Pearson Chi-Square test, a test for independence
Is used to examine the relationship between two qualitative variables.
Involves two qualitative variables
The null hypothesis: There is no association (relationship) between the two variables
The alternative hypothesis: The two variables are associated
Assumptions:
Random Sample: The sample should be randomly selected from the population
Independence: Observations must be independent from each other (Not matched pairs)
Introduction
See Chapter 7- section 7.2 for more details
2
Assumptions:
Adequate sample size :
No more than 20% of the cells having expected count < 5
The expected frequency (count) in each cell must be ≥1
If the expected frequencies are too small then FISHER’S EXACT TEST should be used in place of the Pearson Chi-square
If independence cannot be assumed then another non-parametric test called the MCNEMAR test must be used
Scenario when you would use Chi-Square test:
Does smoking status at baseline depend on gender?
Is there a relationship between coffee consumption and age group?
Introduction
3
Chi-Square Test Statistics
2 Qualitative (Nominal)
Variables
Ho : There is no association between the 2 variables
(2 vars. are indep.)
Ha : There is an association between the 2 variables
(2 vars. not indep.)
Contingency Table Analysis
All assumptions are met
Pearson Chi-Square
Sample size assumption is not met (the expected frequencies are too small)
Fisher’ Exact Test
The assumption of independence is not met. (Paired observation)
McNemar Test
| Evidence or Proof | |
| P-value (Sig.) | If p-value ≤ 0.05, we reject the null hypothesis |
| If p-value > 0.05, we fail to reject the null hypothesis |
Question 1. Is there a relationship between marital status and gender?
Answer:
Hypothesis:
Assumptions:
Random Sample: The sample is randomly selected from the population Met
Independence: Observations are independent from each other (Not matched pairs) Met
Sample Size:
No more than 20% of the cells having expected frequency (count) < 5 Yes No
The expected frequency (count) in each cell must be ≥1 Yes No
See the SPSS outputs (slide 9)
7
Answer:
To Obtain Chi-Square:
From the menus choose:
Analyze Descriptive Statistics Crosstabs option Select marital status as the row variable Select gender as the column variable Click Cells and select column and row percentages Click continue Click statistics option and select Chi-square Click continue then ok
.
8
Assumptions met
SPSS outputs:
Since we have two qualitative variables and all the assumptions are met, Pearson Chi-Square should be used to answer this research question.
9
Summary Table:
Decision:
Fail to reject the null hypothesis (FTR) √ Reject
Since P-value greater than alpha = 0.05, we fail to reject the null hypothesis.
Conclusion (Interpretation):
There is no relationship between marital status and gender
Column %
10
Question 2. Is there a relationship between marital status and BMI categories at baseline?
Answer:
Hypothesis:
Assumptions:
Random Sample: we will that the sample are randomly selected from the population Met
Independence: Observations are independent from each other ( Not matched pairs) Met
Sample Size:
No more than 20% of the cells having expected frequency (count) < 5 Yes No
The expected frequency (count) in each cell must be ≥1 Yes No
See the SPSS output (slide 13)
11
Answer:
To Obtain Chi-Square:
From the menus choose:
Analyze Descriptive Statistics Crosstabs option Select BMI categories at baseline as the row variable Select marital status as the column variable Click Cells and select column and row percentages Click continue Click statistics option and select Chi-square Click continue then ok
.
12
Assumption is not met
SPSS outputs:
Since we have two qualitative variables and not all the assumptions are met, Fisher’s Exact test should be used to answer this research question.
13
Answer:
To Obtain Fisher’s Exact Test:
From the menus choose:
Analyze Descriptive Statistics Crosstabs option Select BMI categories at baseline as the row variable Select marital status as the column variable Click Cells and select column and row percentages Click continue
Click statistics option and select Chi-square Click Exact option and select Monte Carlo with 99%CI Click continue then ok
.
14
SPSS outputs:
15
Summary Table:
Decision:
Fail to reject the null hypothesis (FTR) √ Reject
Since P-value greater than alpha = 0.05, we fail to reject the null hypothesis.
Conclusion (Interpretation):
There is no association between marital status and BMI categories at baseline
16
:
o
Thereisnoassociationbetweenthetwovariabl
es
H
:
a
Thereisanassociationbetweenthetwovariabl
es
H
N %N%
SINGLE53.1%114.5%
MARRIED13886.8%19278.0%
Other1610.1%4317.5%
Chi-square value (2, N=405) = 4.98, p-value =0.083)
MaleFemale
Marital Status
P-value*
0.083
Confounding
| Basic Model | 1.044 | 0.638 | 1.711 | |||||
| Adjusted for Smoking | 1.086 | 0.652 | 1.806 | 4.02 | 2.19 | 5.55 | ||
| Adjusted for Exercise | 1.075 | 0.644 | 1.794 | 2.97 | 0.94 | 4.85 | ||
| Adjusted for BMI | 1.258 | 0.744 | 2.127 | 20.50 | 16.61 | 24.31 |
Descriptive I
| Table 1 – General Characteristics of Study Paticipants | ||
| Characteristics | Study Participants | |
| n | ||
| Age,yeara | ||
| Body Mass Indexa | ||
| Stressd | ||
| Low | ||
| High | ||
| Genderc | ||
| Male | ||
| Female | ||
| Smokingd | ||
| Never | ||
| Ever | ||
| Exercisec | ||
| None | ||
| Mild | ||
| Moderate / Vigorous | ||
| a Value are means± SD | ||
| bValue are median(range) | ||
| cValue are number (Percentages) | ||
| dValid perecentages are used due to missing values |
Descriptive II
| Table 2 – General Characteristics of Study Paticipants Stratified by Hypertention Status | ||||
| Characteristics | Hypertention Status | P-value§ | ||
| Normal | Abnormal | |||
| n= | n= | |||
| Age,yeara | ||||
| Body Mass Indexa | ||||
| Stressb | ||||
| Low | ||||
| High | ||||
| Genderb | ||||
| Male | ||||
| Female | ||||
| Smokingb | ||||
| Never | ||||
| Ever | ||||
| Exerciseb | ||||
| None | ||||
| Mild | ||||
| Moderate / Vigorous | ||||
| a Value are means± SD | ||||
| bValue are number (Percentages) | ||||
| § The independent t test was used for quantitaive variables and Chi-square test was used for qualitative variables |
Logisitc Regression
| Final Model | |||||
| Table 3. Multiple LogisticRegression Analysis of the Effect of Stress on Hypertension After Adjusting for Age and Gender | |||||
| Odds ratio | 95% C.I.for Odds ratio | P-value | |||
| Lower | Upper | ||||
| Stress | |||||
| High | |||||
| Low | Reference | ||||
| Gender | |||||
| Male | |||||
| Female | Reference | ||||
| Age | |||||
| BMI | |||||
| Table 3: Odds ratios ( 95% confidence interval) for Multiple Logistic Regression | |||||
| Stress | |||||
| Odds Ratio (High vs Low) | 95% CI | p-value | |||
| Unadjusted model | |||||
| Adjusted model for gender and age only | |||||
| Adjusted model for age gender and BMI |
Sheet1
| Gender | P-value* | ||||||
| Male | Female | ||||||
| N | % | N | % | ||||
| Marital Status | SINGLE | 5 | 3.1% | 11 | 4.5% | 0.083 | |
| MARRIED | 138 | 86.8% | 192 | 78.0% | |||
| Other | 16 | 10.1% | 43 | 17.5% | |||
| Chi-square value (2, N=405) = 4.98, p-value =0.083) |
N %N %N %
Normal637.5%8826.7%1118.6%
Overweight637.5%14042.4%2949.2%
Obese425.0%10230.9%1932.2%
BMI Categories at
Baseline
P-value**
0.560
**Fisher's Exact value = 2.98,
p
-value =0.560
Marital Status
SingleMarriedOther
Confounding
| Basic Model | 1.044 | 0.638 | 1.711 | |||||
| Adjusted for Smoking | 1.086 | 0.652 | 1.806 | 4.02 | 2.19 | 5.55 | ||
| Adjusted for Exercise | 1.075 | 0.644 | 1.794 | 2.97 | 0.94 | 4.85 | ||
| Adjusted for BMI | 1.258 | 0.744 | 2.127 | 20.50 | 16.61 | 24.31 |
Descriptive I
| Table 1 – General Characteristics of Study Paticipants | |||
| Characteristics | Study Participants | ||
| n | |||
| Age,year | a | ||
| Body Mass Index | a | ||
| Stress | d | ||
| Low | |||
| High | |||
| Gender | c | ||
| Male | |||
| Female | |||
| Smoking | d | ||
| Never | |||
| Ever | |||
| Exercise | c | ||
| None | |||
| Mild | |||
| Moderate / Vigorous | |||
| a | Value are means± SD | ||
| b | Value are median(range) | ||
| c | Value are number (Percentages) | ||
| d | Valid perecentages are used due to missing values |
Descriptive II
| Table 2 – General Characteristics of Study Paticipants Stratified by Hypertention Status | |||||
| Characteristics | Hypertention Status | P-value | § | ||
| Normal | Abnormal | ||||
| n= | n= | ||||
| Age,year | a | ||||
| Body Mass Index | a | ||||
| Stress | b | ||||
| Low | |||||
| High | |||||
| Gender | b | ||||
| Male | |||||
| Female | |||||
| Smoking | b | ||||
| Never | |||||
| Ever | |||||
| Exercise | b | ||||
| None | |||||
| Mild | |||||
| Moderate / Vigorous | |||||
| a | Value are means± SD | ||||
| b | Value are number (Percentages) | ||||
| § | The independent t test was used for quantitaive variables and Chi-square test was used for qualitative variables |
Logisitc Regression
| Final Model | |||||
| Table 3. Multiple LogisticRegression Analysis of the Effect of Stress on Hypertension After Adjusting for Age and Gender | |||||
| Odds ratio | 95% C.I.for Odds ratio | P-value | |||
| Lower | Upper | ||||
| Stress | |||||
| High | |||||
| Low | Reference | ||||
| Gender | |||||
| Male | |||||
| Female | Reference | ||||
| Age | |||||
| BMI | |||||
| Table 3: Odds ratios ( 95% confidence interval) for Multiple Logistic Regression | |||||
| Stress | |||||
| Odds Ratio (High vs Low) | 95% CI | p | -value | ||
| Unadjusted model | |||||
| Adjusted model for gender and age only | |||||
| Adjusted model for age gender and BMI |
Sheet1
| Gender | P-value | ||||||||
| Male | Female | ||||||||
| N | % | N | % | ||||||
| Marital Status | SINGLE | 5 | 3.1% | 11 | 4.5% | ||||
| MARRIED | 138 | 86.8% | 192 | 78.0% | |||||
| Other | 16 | 10.1% | 43 | 17.5% | |||||
| Marital Status | P-value** | ||||||||
| Single | Married | Other | |||||||
| N | % | N | % | N | % | ||||
| BMI Categories at Baseline | Normal | 6 | 37.5% | 88 | 26.7% | 11 | 18.6% | 0.560 | |
| Overweight | 6 | 37.5% | 140 | 42.4% | 29 | 49.2% | |||
| Obese | 4 | 25.0% | 102 | 30.9% | 19 | 32.2% | |||
| **Fisher's Exact value = 2.98, | p | -value =0.560 |