BIO LABS

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Experiment Human Genetics

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Human Genetics

Margaret E. Vorndam, M.S. Version 42-0068-00-01

Lab Report Assistant

This document is not meant to be a substitute for a formal laboratory report. The Lab Report Assistant is simply a summary of the experiment’s questions, diagrams if needed, and data tables that should be addressed in a formal lab report. The intent is to facilitate students’ writing of lab reports by providing this information in an editable file which can be sent to an instructor.

Observations

Data Table 1: Single-Gene Traits of a Selected Population

Subject # > 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Total

XX Female XX

XY Male

FF,Ff = unattached

ff = attached ff

RR,Rr = roller R

rr = can’t roll

SS,Ss = straight thumb

ss = bent thumb ss

MM,Mm = hair

mm = no hair

TT,Tt = left on top T

tt = right on top

LL,Ll = two tendons L

ll = three tendons

Experiment Human Genetics

280 ©Hands-On Labs, Inc. www.HOLscience.com

Exercise 1: Patterns in Human Inheritance Traits Questions

A. What observations can be made about the collected and charted data?

B. Are any two people exactly the same? If so, how closely are they related?

C. Is your hypothesis supported by the findings? What statistical tool might help you to make this decision?

D. In the totals that you recorded in Table 1, did you find that the number of dominant phenotypes were greater than, equal to, or less than the recessive phenotypes?

E. Can you explain what possible genotypes are suggested by this pattern? Does this vary by trait?

F. Would you expect this outcome? Why or why not?

G. How would changing the level of the mapped traits affect the chart? For instance, if the alleles for male or female were on the outer rim of the chart, rather than in the middle, how would the pattern observed differ from Figure 10-1?

Experiment Human Genetics

H. List several other traits that humans have that are governed by genetics.

I. Would your data vary if you went to another part of the world, for instance, China?

J. Why might collected data show different patterns for different cultural populations?

K. Would you expect that the pattern would be different if collected 100 years ago instead of today? Why or why not?

L. If you had percentages of dominant and recessive genes present for the total number of alleles of a trait for the entire world, would you expect that percentage to change over 100 years? Why or why not?

Experiment Human Genetics

Exercise 2: Human Chromosomes and the Human Genome Project Results

Report on your findings. Your report should be limited to a page in length and may incorporate the outline of research points above.

Experiment Human Genetics

Questions

A. What is the purpose of this exercise?

B. What is the prognosis on genetic diseases in the future? Do you believe that microsurgery to “fix” chromosomal aberrations will some day prevent the diseases that are listed in the List of Genetically Mediated Diseases in Humans?

Laboratory Summary

What have you learned from doing this laboratory?

References