Anatomy Physiology

Week 2 Response need to classmate post> 150 words Anatomy physicology

Review tissue damage, inflammation and tissue repair by reviewing an example of this in any part of the body . If you are walking barefoot and step on a nail and it penetrates your skin(epidermis), this will cause tissue damage. The penetrated area of the foot will begin to feel pain, the area around the break will bleed(because of ruptured blood vessels), swell and turn red. The area may even feel a bit more warm then the rest of your foot. This is a result of inflammation. The body is isolating harmful agents(bacteria from the nail)  from the rest of the body, using chemical mediators which cause these symptoms. Dilation of the blood vessels(heat and redness), is helping white blood cells to move quickly to the injured site to help fight infection. The pain is cause by edema which is a result of  clotting proteins and osmosis moving to the damaged tissues also causing the swelling. These responses will look like a wound filling up with blood and over time beginning to clot.The white blood cells, called neutrophils, will ingest all the bacteria and tissue debris clearing the area for repair. Regeneration will occur and new cells with the same function will develop. The  epithelial tissues cells are classified as labile, meaning they can continue divide through out their life. Stepping on a nail should heal through primary union.  The edges are close enough together. While. the wound is filled with blood a clot will form, filled with fibrin, when it dries it will form a scab, sealing the wound from infection. During the scabbing the neutrophils are killed and can accumulate as pus. Fibroblasts from the surrounding connective tissue migrate into the clot and produce collagen and other extracellular matrix components. Capillaries will begin to grow and the clot will be replaced by granulation tissue. Granulation tissue is fibroblasts, collagen and capillaries  Granulation tissue turns into a scar,  the scar will be bright red as a result of the amount of blood vessels present, it then whitens as the amount of collagen increases and then the vascular channels are compressed.