MITOSIS

MITOSIS Lab Below is a listing which will help you to prepare for the quiz and lab on this material.

CONTENT TO KNOW:

I. Mitosis - a process of nuclear division which produces daughter cells that are genetically identical to the parent DNA. Purpose: growth and development

II. The Cell Cycle – the cell spends 90% of its time in INTERPHASE; only a small portion of the time is it undergoing MITOSIS (actual division); interphase consists of 3 phases:

INTERPHASE has 3 stages: • G1 - growth phase (or GAP) • S - synthesis phase, DNA duplicated (replicated) o G2 - growth phase (or GAP), cell gets ready to divide

Click Here for an IMAGE of the Cell Cycle

III. Chromosomes – each chromosome is one molecule of DNA complexed with

proteins

Click Here for an IMAGE of Chromosomes, duplicating Diploid Cells – those cells which have PAIRS of chromosomes; in humans the total number of chromosomes in a diploid cell = 46 (23 pairs) Haploid Cells – those cells which have HALF the number (23 in humans)

IV. The 4 Stages of Mitosis –

(PMAT) Prophase- • DNA condenses (thickens)

Metaphase- • The chromosomes line up at the spindle equator, aka the metaphase plate (middle) and

each chromatid is oriented toward opposite poles.

Anaphase- o The sister chromatids are separated

Telophase – o 2 new cells form; new nucleus in both cells; separation

Click Here for IMAGES of Interphase & Prophase Click Here for IMAGEs of Metaphase, Anaphase & Telophase

Click Here for a VIDEO on Mitosis **Be sure you can identify the stages of mitosis in the pictures; the major difference between INTERPHASE and PROPHASE is that in prophase you can actually see the strands of chromosomes; they are not visible in Interphase.