Statistics analysis

profilert211r
lms.xlsx

Sheet1

From the data below, you must make a recommendation on the allowable maximum exposure to members of the public of 1-3 baloneydiene.
·         You agency prescribes using the LMS (linearized multistage model)
·         Maximum allowable dose is that which is 95% certain to result in life time cancer probability of
or less
·         Report
Rat dose of 1,3 baloneydiene D[mg/kg/d] Number of rats, n Number of rats with tumors, s
0 70 8
6.25 70 26
20 70 33
62.5 70 41
200 70 48