Translocation of BCR ABL gene chromosome 9 to 22 , chronic myeloid leukemia

Topic: Discuss the pathological and prognostic impact of gene fusion in blood cancer.

Key points:

1- the normal function of gene before the fusion event

2- the altered function of gene post fusion

3-How the altered function of fused genes affects the disease progression/initiation

4- How the altered function of fused genes affects the disease prognosis

5- Text paraphrasing should be applied as the text will be scanned for text similarity

6- Make a good use of referencing system of your choice

8 the format of the text is: Abstract--> introduction-->body of the topic ---> conclusion.

9- Reference should include text books and papers.