Pharmacogenomics of Tetrabenazine

Pharmacogenomics influences how drugs are metabolized and transported (pharmacokinetics) as well as the drug’s ability to exert a clinical effect (pharmacodynamics). Being aware of these factors is important when prescribing. The purpose of this assignment is to enhance your pharmacogenomic knowledge as well as educate your peers. You will and investigate the following of the drug Tetrabenazine: 

Basic Pharmacodynamics and Pharmacokinetics of Tetrabenazine

Pharmacogenomic Variation That can be seen in clinical practice

Racial/cultural variations

Impact on incidence of drug interactions and adverse effects

Available testing as well as if it is currently being used (why or why not)  

How these factors can or should influence prescribing practices/clinical implications