Nursing Assignment

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NU553_Unit_2_Template.docx

NU553 Unit 2 Template

Review the grading rubric.

Antimicrobials and Antibiotic Stewardship

Student Name:

Date:

Instructor Name:

Introduction.

Legal/ Ethical and Regulatory Considerations.

Communication Civility

Cost- Effective Benefits.

Antimicrobial Stewardship.

Antimicrobial Agents

Drug Class

Drug Name

Brand/

Generic

Mechanism of action

Pharmacokinetics Key points

Microbiology

Key points

Indications and Uses

Dose via Age and Dose

Considerations

Warnings

Penicillins

Penicillin G

(Penicillin G 2025)

Beta-lactam antibiotic, interferes with bacteria cell wall synthesis ultimately leading to cell lysis

Protein bound to albumin in circulation

Crosses placenta and breast milk

Excreted in urine primarily

Gram + Bacteria.

Streptococcus pyogenes,

S. pneumoniae

enterococcal

Some gram-neg: meningeal cocci

treponemal infections-syphilis

meningococcal bacteremia

Endocarditis

Botulism

Pneumonia

4-24 million units per day based on indication.

IV most often since poorly absorbed in the gut

Can be IM for short term indication

Allergy

CHF related due to sodium content

Dose adjustment for renal impairment

Beta-Lactam/

Beta Lactamase Inhibitor

1st Generation Cephalosporin

Fluoroquinolone

Macrolide

Aminoglycoside

Tetracycline

Sulfonamide

Fusion Inhibitor

Nucleoside Analogs

Protease Inhibitor

References

Penicillin G. (2025). Merck Manual https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-medications/penicillins?query=pen%20vk#Pharmacokinetics_v13957234