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nw10instructions.docx
NSG120Week10HematologyDiagnosticTestGrid2022.docx

nw10instructions.docx

Please use the document below to complete the following activities:

· Complete Gray Boxes and Highlighted Areas.

· Submit to the Canvas Dropbox.

· Submissions must be handwritten.

NSG120Week10HematologyDiagnosticTestGrid2022.docx

Hematology System Diagnostic Test Grid Name: _________________________

Name of Test	Test Type	Normal Adult Findings	Indications for Test	Interfering Factors & Contraindications	Clinical Significance of Findings
RBC, WBC, Platelet, Hgb, Hct, CBC with differentials, Platelets	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid
Erythrocyte Sedimentation Rate (ESR)	Blood Test
Peripheral Blood Smear	Blood Test	Normal quantity of red blood cells (RBCs), white blood cells (WBCs), and platelets. Normal size, shape, and color of RBCs. Normal WBC differential count	Can identify concerning drugs and diseases that affect the RBCs, WBCs, or platelets. Some congenital and acquired diseases can be diagnosed by an examination of the peripheral blood smear. Infection, infestation, leukemia, and other diseases can be identified with special stains.	The smear being delayed after the blood is collected can alter the results. Not enough or too large amount of blood collected. Failure to apply to blood correctly to the slide.	Red Blood Cell (RBC) size, shape, color and intracellular structure abnormalities- can help identify causes of anemia and the presence of other diseases. White blood cell (WBC) examination- increased numbers can indicate leukemia or infection. Platelet examination- can determine platelet numbers that help to promote clotting.
Coombs Test, Direct	Blood Test	Normal, no agglutination	To identify immune hemolysis or to investigate hemolytic transfusion reactions	Antiphospholipid antibodies and some drugs can cause a false positive	Will identify hemolytic anemia, blood transfusion reactions, infectious mononucleosis, or blood transfusion reactions
Sickle Cell Screen	Blood Study	Negative, no sickle cells present	To screen for sickle cell disease or trait	Blood transfusions within 3-4 months, polycythemia, or certain drugs can alter results	Will identify if a patient has the sickle cell trait or sickle cell anemia. Sickle cell anemia more than 25% of the Hgb is the S variation
Folic Acid	Blood Test
Ferritin	Blood Test
Iron	Blood Test
Vitamin B12	Blood Test	160-950 pg/mL	Used to identify the cause of megaloblastic anemia	Certain drugs can decrease Vit B12 levels	Measures the amount of Vitamin B12 in the blood. Decreased levels are a sign of anemia. Increased levels (as well as decreased levels) are signs of other conditions
Erythropoietin	Blood Test	5-35 international units/L	Used to assist in differentiating the cause of anemia or polycythemia	Pregnancy can cause elevated levels. Transfused blood decreases levels. Certain drugs (SCTH, birth control pills and steroids) can increase levels.	Increased levels- Iron- deficiency, hemolytic or megaloblastic anemia, AIDS, renal cell or adrenal carcinoma. Decreased levels- Polycythemia vera:
Prothrombin Time/International Normalized Ratio (PT/INR)	Blood Test
Partial Thromboplastin Time (PTT)	Blood Test
Blood Typing	Blood test	Compatibility	Used to determine the blood type of the patient before receiving blood or the expectant mother to assess the risks of Rh incompatibility between mother and newborn.	Non-ABO or non-Rh minor antibodies can interfere with obtaining an adequate crossmatch.	Can determine ABO type (A, B, AB or O), Rh Type (positive or negative) and Crossmatch compatibility.
D-Dimer	Blood Test	<0.4 mcg/mL	Used to identify intravascular clotting	Patients with high lipid levels or high levels of rheumatoid factor may alter results	Increased levels may indicate the patient has DIC, or a thromboembolism. May also be elevated with surgery, cancer, or pregnancy
Fibrinogen	Blood test	60-100 mg/dL	To help aid in the diagnosis of suspected bleeding disorders. It is also used for monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.	Blood transfusions within the past month, diets rich in omega-3 and omega-6 fatty acids, drugs that alter the levels	Increased levels: Acute inflammatory reactions (RA), acute infection pneumonia), coronary heart disease, stroke, peripheral vascular disease, pregnancy, smoking Decreased levels: Liver disease (hepatitis, cirrhosis), advanced carcinoma, malnutrition (severe protein depletion), large- volume blood transfusion
DIC Screening	Blood test	No evidence of DIC	For patients who are suspected of having DIC, have chronic DIC, or are at risk for DIC	N/A	Should be evaluated for patients with a coagulopathy or patients with a diagnosis of sepsis or advanced cancer
Bone Marrow Biopsy	Procedural needle biopsy	Active erythroid cell line, myeloid and lymphoid cell lines, and megakaryocyte (platelet) production	To evaluate anemias, leukopenia, or thrombocytopenia. To diagnose leukemia and myelodysplastic syndromes. Used to assess abnormal iron states and to stage lymphomas or other cancers.	Contraindicated in patients that can’t comprehend an informed consent, can’t cooperate and remain still for the procedure or have acute coagulation disorders.	Can determine types of infections (Bacterial, viral or fungal), Multiple myelomas, Hodgkin's disease, lymphoma, leukemia, anemia and rheumatic fever

NSG120Week10HematologyDiagnosticTestGrid2022.docx

Hematology System Diagnostic Test Grid Name: _________________________

Name of Test	Test Type	Normal Adult Findings	Indications for Test	Interfering Factors & Contraindications	Clinical Significance of Findings
RBC, WBC, Platelet, Hgb, Hct, CBC with differentials, Platelets	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid
Erythrocyte Sedimentation Rate (ESR)	Blood Test
Peripheral Blood Smear	Blood Test	Normal quantity of red blood cells (RBCs), white blood cells (WBCs), and platelets. Normal size, shape, and color of RBCs. Normal WBC differential count	Can identify concerning drugs and diseases that affect the RBCs, WBCs, or platelets. Some congenital and acquired diseases can be diagnosed by an examination of the peripheral blood smear. Infection, infestation, leukemia, and other diseases can be identified with special stains.	The smear being delayed after the blood is collected can alter the results. Not enough or too large amount of blood collected. Failure to apply to blood correctly to the slide.	Red Blood Cell (RBC) size, shape, color and intracellular structure abnormalities- can help identify causes of anemia and the presence of other diseases. White blood cell (WBC) examination- increased numbers can indicate leukemia or infection. Platelet examination- can determine platelet numbers that help to promote clotting.
Coombs Test, Direct	Blood Test	Normal, no agglutination	To identify immune hemolysis or to investigate hemolytic transfusion reactions	Antiphospholipid antibodies and some drugs can cause a false positive	Will identify hemolytic anemia, blood transfusion reactions, infectious mononucleosis, or blood transfusion reactions
Sickle Cell Screen	Blood Study	Negative, no sickle cells present	To screen for sickle cell disease or trait	Blood transfusions within 3-4 months, polycythemia, or certain drugs can alter results	Will identify if a patient has the sickle cell trait or sickle cell anemia. Sickle cell anemia more than 25% of the Hgb is the S variation
Folic Acid	Blood Test
Ferritin	Blood Test
Iron	Blood Test
Vitamin B12	Blood Test	160-950 pg/mL	Used to identify the cause of megaloblastic anemia	Certain drugs can decrease Vit B12 levels	Measures the amount of Vitamin B12 in the blood. Decreased levels are a sign of anemia. Increased levels (as well as decreased levels) are signs of other conditions
Erythropoietin	Blood Test	5-35 international units/L	Used to assist in differentiating the cause of anemia or polycythemia	Pregnancy can cause elevated levels. Transfused blood decreases levels. Certain drugs (SCTH, birth control pills and steroids) can increase levels.	Increased levels- Iron- deficiency, hemolytic or megaloblastic anemia, AIDS, renal cell or adrenal carcinoma. Decreased levels- Polycythemia vera:
Prothrombin Time/International Normalized Ratio (PT/INR)	Blood Test
Partial Thromboplastin Time (PTT)	Blood Test
Blood Typing	Blood test	Compatibility	Used to determine the blood type of the patient before receiving blood or the expectant mother to assess the risks of Rh incompatibility between mother and newborn.	Non-ABO or non-Rh minor antibodies can interfere with obtaining an adequate crossmatch.	Can determine ABO type (A, B, AB or O), Rh Type (positive or negative) and Crossmatch compatibility.
D-Dimer	Blood Test	<0.4 mcg/mL	Used to identify intravascular clotting	Patients with high lipid levels or high levels of rheumatoid factor may alter results	Increased levels may indicate the patient has DIC, or a thromboembolism. May also be elevated with surgery, cancer, or pregnancy
Fibrinogen	Blood test	60-100 mg/dL	To help aid in the diagnosis of suspected bleeding disorders. It is also used for monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.	Blood transfusions within the past month, diets rich in omega-3 and omega-6 fatty acids, drugs that alter the levels	Increased levels: Acute inflammatory reactions (RA), acute infection pneumonia), coronary heart disease, stroke, peripheral vascular disease, pregnancy, smoking Decreased levels: Liver disease (hepatitis, cirrhosis), advanced carcinoma, malnutrition (severe protein depletion), large- volume blood transfusion
DIC Screening	Blood test	No evidence of DIC	For patients who are suspected of having DIC, have chronic DIC, or are at risk for DIC	N/A	Should be evaluated for patients with a coagulopathy or patients with a diagnosis of sepsis or advanced cancer
Bone Marrow Biopsy	Procedural needle biopsy	Active erythroid cell line, myeloid and lymphoid cell lines, and megakaryocyte (platelet) production	To evaluate anemias, leukopenia, or thrombocytopenia. To diagnose leukemia and myelodysplastic syndromes. Used to assess abnormal iron states and to stage lymphomas or other cancers.	Contraindicated in patients that can’t comprehend an informed consent, can’t cooperate and remain still for the procedure or have acute coagulation disorders.	Can determine types of infections (Bacterial, viral or fungal), Multiple myelomas, Hodgkin's disease, lymphoma, leukemia, anemia and rheumatic fever

nw10instructions.docx

Please use the document below to complete the following activities:

· Complete Gray Boxes and Highlighted Areas.

· Submit to the Canvas Dropbox.

· Submissions must be handwritten.

NSG120Week10HematologyDiagnosticTestGrid2022.docx

Hematology System Diagnostic Test Grid Name: _________________________

Name of Test	Test Type	Normal Adult Findings	Indications for Test	Interfering Factors & Contraindications	Clinical Significance of Findings
RBC, WBC, Platelet, Hgb, Hct, CBC with differentials, Platelets	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid
Erythrocyte Sedimentation Rate (ESR)	Blood Test
Peripheral Blood Smear	Blood Test	Normal quantity of red blood cells (RBCs), white blood cells (WBCs), and platelets. Normal size, shape, and color of RBCs. Normal WBC differential count	Can identify concerning drugs and diseases that affect the RBCs, WBCs, or platelets. Some congenital and acquired diseases can be diagnosed by an examination of the peripheral blood smear. Infection, infestation, leukemia, and other diseases can be identified with special stains.	The smear being delayed after the blood is collected can alter the results. Not enough or too large amount of blood collected. Failure to apply to blood correctly to the slide.	Red Blood Cell (RBC) size, shape, color and intracellular structure abnormalities- can help identify causes of anemia and the presence of other diseases. White blood cell (WBC) examination- increased numbers can indicate leukemia or infection. Platelet examination- can determine platelet numbers that help to promote clotting.
Coombs Test, Direct	Blood Test	Normal, no agglutination	To identify immune hemolysis or to investigate hemolytic transfusion reactions	Antiphospholipid antibodies and some drugs can cause a false positive	Will identify hemolytic anemia, blood transfusion reactions, infectious mononucleosis, or blood transfusion reactions
Sickle Cell Screen	Blood Study	Negative, no sickle cells present	To screen for sickle cell disease or trait	Blood transfusions within 3-4 months, polycythemia, or certain drugs can alter results	Will identify if a patient has the sickle cell trait or sickle cell anemia. Sickle cell anemia more than 25% of the Hgb is the S variation
Folic Acid	Blood Test
Ferritin	Blood Test
Iron	Blood Test
Vitamin B12	Blood Test	160-950 pg/mL	Used to identify the cause of megaloblastic anemia	Certain drugs can decrease Vit B12 levels	Measures the amount of Vitamin B12 in the blood. Decreased levels are a sign of anemia. Increased levels (as well as decreased levels) are signs of other conditions
Erythropoietin	Blood Test	5-35 international units/L	Used to assist in differentiating the cause of anemia or polycythemia	Pregnancy can cause elevated levels. Transfused blood decreases levels. Certain drugs (SCTH, birth control pills and steroids) can increase levels.	Increased levels- Iron- deficiency, hemolytic or megaloblastic anemia, AIDS, renal cell or adrenal carcinoma. Decreased levels- Polycythemia vera:
Prothrombin Time/International Normalized Ratio (PT/INR)	Blood Test
Partial Thromboplastin Time (PTT)	Blood Test
Blood Typing	Blood test	Compatibility	Used to determine the blood type of the patient before receiving blood or the expectant mother to assess the risks of Rh incompatibility between mother and newborn.	Non-ABO or non-Rh minor antibodies can interfere with obtaining an adequate crossmatch.	Can determine ABO type (A, B, AB or O), Rh Type (positive or negative) and Crossmatch compatibility.
D-Dimer	Blood Test	<0.4 mcg/mL	Used to identify intravascular clotting	Patients with high lipid levels or high levels of rheumatoid factor may alter results	Increased levels may indicate the patient has DIC, or a thromboembolism. May also be elevated with surgery, cancer, or pregnancy
Fibrinogen	Blood test	60-100 mg/dL	To help aid in the diagnosis of suspected bleeding disorders. It is also used for monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.	Blood transfusions within the past month, diets rich in omega-3 and omega-6 fatty acids, drugs that alter the levels	Increased levels: Acute inflammatory reactions (RA), acute infection pneumonia), coronary heart disease, stroke, peripheral vascular disease, pregnancy, smoking Decreased levels: Liver disease (hepatitis, cirrhosis), advanced carcinoma, malnutrition (severe protein depletion), large- volume blood transfusion
DIC Screening	Blood test	No evidence of DIC	For patients who are suspected of having DIC, have chronic DIC, or are at risk for DIC	N/A	Should be evaluated for patients with a coagulopathy or patients with a diagnosis of sepsis or advanced cancer
Bone Marrow Biopsy	Procedural needle biopsy	Active erythroid cell line, myeloid and lymphoid cell lines, and megakaryocyte (platelet) production	To evaluate anemias, leukopenia, or thrombocytopenia. To diagnose leukemia and myelodysplastic syndromes. Used to assess abnormal iron states and to stage lymphomas or other cancers.	Contraindicated in patients that can’t comprehend an informed consent, can’t cooperate and remain still for the procedure or have acute coagulation disorders.	Can determine types of infections (Bacterial, viral or fungal), Multiple myelomas, Hodgkin's disease, lymphoma, leukemia, anemia and rheumatic fever

NSG120Week10HematologyDiagnosticTestGrid2022.docx

Hematology System Diagnostic Test Grid Name: _________________________

Name of Test	Test Type	Normal Adult Findings	Indications for Test	Interfering Factors & Contraindications	Clinical Significance of Findings
RBC, WBC, Platelet, Hgb, Hct, CBC with differentials, Platelets	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid	See Basic Diagnostic Test Grid
Erythrocyte Sedimentation Rate (ESR)	Blood Test
Peripheral Blood Smear	Blood Test	Normal quantity of red blood cells (RBCs), white blood cells (WBCs), and platelets. Normal size, shape, and color of RBCs. Normal WBC differential count	Can identify concerning drugs and diseases that affect the RBCs, WBCs, or platelets. Some congenital and acquired diseases can be diagnosed by an examination of the peripheral blood smear. Infection, infestation, leukemia, and other diseases can be identified with special stains.	The smear being delayed after the blood is collected can alter the results. Not enough or too large amount of blood collected. Failure to apply to blood correctly to the slide.	Red Blood Cell (RBC) size, shape, color and intracellular structure abnormalities- can help identify causes of anemia and the presence of other diseases. White blood cell (WBC) examination- increased numbers can indicate leukemia or infection. Platelet examination- can determine platelet numbers that help to promote clotting.
Coombs Test, Direct	Blood Test	Normal, no agglutination	To identify immune hemolysis or to investigate hemolytic transfusion reactions	Antiphospholipid antibodies and some drugs can cause a false positive	Will identify hemolytic anemia, blood transfusion reactions, infectious mononucleosis, or blood transfusion reactions
Sickle Cell Screen	Blood Study	Negative, no sickle cells present	To screen for sickle cell disease or trait	Blood transfusions within 3-4 months, polycythemia, or certain drugs can alter results	Will identify if a patient has the sickle cell trait or sickle cell anemia. Sickle cell anemia more than 25% of the Hgb is the S variation
Folic Acid	Blood Test
Ferritin	Blood Test
Iron	Blood Test
Vitamin B12	Blood Test	160-950 pg/mL	Used to identify the cause of megaloblastic anemia	Certain drugs can decrease Vit B12 levels	Measures the amount of Vitamin B12 in the blood. Decreased levels are a sign of anemia. Increased levels (as well as decreased levels) are signs of other conditions
Erythropoietin	Blood Test	5-35 international units/L	Used to assist in differentiating the cause of anemia or polycythemia	Pregnancy can cause elevated levels. Transfused blood decreases levels. Certain drugs (SCTH, birth control pills and steroids) can increase levels.	Increased levels- Iron- deficiency, hemolytic or megaloblastic anemia, AIDS, renal cell or adrenal carcinoma. Decreased levels- Polycythemia vera:
Prothrombin Time/International Normalized Ratio (PT/INR)	Blood Test
Partial Thromboplastin Time (PTT)	Blood Test
Blood Typing	Blood test	Compatibility	Used to determine the blood type of the patient before receiving blood or the expectant mother to assess the risks of Rh incompatibility between mother and newborn.	Non-ABO or non-Rh minor antibodies can interfere with obtaining an adequate crossmatch.	Can determine ABO type (A, B, AB or O), Rh Type (positive or negative) and Crossmatch compatibility.
D-Dimer	Blood Test	<0.4 mcg/mL	Used to identify intravascular clotting	Patients with high lipid levels or high levels of rheumatoid factor may alter results	Increased levels may indicate the patient has DIC, or a thromboembolism. May also be elevated with surgery, cancer, or pregnancy
Fibrinogen	Blood test	60-100 mg/dL	To help aid in the diagnosis of suspected bleeding disorders. It is also used for monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.	Blood transfusions within the past month, diets rich in omega-3 and omega-6 fatty acids, drugs that alter the levels	Increased levels: Acute inflammatory reactions (RA), acute infection pneumonia), coronary heart disease, stroke, peripheral vascular disease, pregnancy, smoking Decreased levels: Liver disease (hepatitis, cirrhosis), advanced carcinoma, malnutrition (severe protein depletion), large- volume blood transfusion
DIC Screening	Blood test	No evidence of DIC	For patients who are suspected of having DIC, have chronic DIC, or are at risk for DIC	N/A	Should be evaluated for patients with a coagulopathy or patients with a diagnosis of sepsis or advanced cancer
Bone Marrow Biopsy	Procedural needle biopsy	Active erythroid cell line, myeloid and lymphoid cell lines, and megakaryocyte (platelet) production	To evaluate anemias, leukopenia, or thrombocytopenia. To diagnose leukemia and myelodysplastic syndromes. Used to assess abnormal iron states and to stage lymphomas or other cancers.	Contraindicated in patients that can’t comprehend an informed consent, can’t cooperate and remain still for the procedure or have acute coagulation disorders.	Can determine types of infections (Bacterial, viral or fungal), Multiple myelomas, Hodgkin's disease, lymphoma, leukemia, anemia and rheumatic fever

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