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myndis3.docx
nr3.docx
myndis3.docx
Instructions:
This week we have explored the Inflammatory Process and Wound Healing. Reviewing everything you’ve learned this week, select one example of an inflammatory condition and one example of an infectious disorder from a wound.
Compare and contrast the causes, signs and symptoms, diagnostic tools, and treatment.
In what ways are they similar?
In what ways are they different?
Please be sure to validate your opinions and ideas with citations and references.
Estimated time to complete: 2 hours
Rheumatoid Arthritis and Cellulitis Similarities and Differences
Inflammatory Process: Rheumatoid Arthritis
It is also referred to as an autoimmune condition and indicates a situation where the immunity of the body, rather than protection, attacks the membrane lining surrounding the joints (Begum, 2024). It results in the inflammation of the lining of the body, making the body joints red, swollen, painful and warm, therefore making it similar to cellulitis. It affects the two sides of the body, including the knees, wrists and hands. The main cause of Rheumatoid Arthritis is not well known. However, it is believed to be a combination of hormonal, environmental and genetic factors. The factor triggers the immune system to attack the joints or other organs, and the risk factors are composed of a family history of RA, body overweight and smoking. The symptoms include joint swelling and pain, fever, fatigue, loss of appetite and stiffness in most cases after sitting for an extended period of time in the morning. The diagnostic tools included are blood tests to check for anemia, C reactive protein (CRP), Rheumatoid factor (RF), Erythrocyte sedimentation rate and cyclic citrulline peptide antibody test. Alternatively, imaging tests such as X-rays assess joint inflammation and damage extent. Rheumatoid Arthritis is treated through medications, exercise, rest or surgery to correct the joint damage.
Infectious Disorder: Cellulitis
On the other hand, cellulitis forms a common bacterial infection of soft tissues underneath the skin. It is similar to Rheumatoid Arthritis as it causes skin pain, swelling, warmth or redness. Even though different bacteria are causing the infection, the main bacteria causing the infection include staphylococcus aureus and Group A streptococcus. It becomes life-threatening after spreading into the bloodstream (Sheikh, 2024). The symptoms include fever, chills, swelling, warmth, redness and pain in the affected area. The diagnosis of cellulitis is via the physician's skin examination, an X-ray to determine a foreign object in the skin and the possibility of infection in the bone underneath. Additionally, bacterial culture enables a doctor to remove the fluid in the affected area and send it to the lab to identify the causative organism. The treatment comprises cellulitis antibiotics, including cephalexin and dicloxacillin, taken through the mouth, and wound care.
References
Begum, J. (2024). Rheumatoid Arthritis: Signs and Treatment. WebMD. https://www.webmd.com/rheumatoid-arthritis/rheumatoid-arthritis-basicsLinks to an external site.
Sheikh, Z. (2024). How to Get Rid of Cellulitis. WebMD. https://www.webmd.com/skin-problems-and-treatments/cellulitisLinks to an external site.
nr3.docx
instructions:
Please read and respond to at least two of your peers' initial responses. In your response, consider the following questions:
Share your findings in your initial post, then respond to two of your peers.
Please be sure to validate your opinions and ideas with citations and references.
Estimated time to complete: 1 hour
When we are in the background of medical issues and education, we cannot fully understand the differences or even similarities that come with the subjects and that plays a major role in our healthcare system. There is so much to learn and understand and for now I can help you understand what inflammation and wound healing is described as, as well as understanding in what ways are they similar and in what ways are they different.
Inflammation is a way that our body responds to something that is hurt or irritated. It can be from anything as a germ or even just a splinter, Inflammation can be diagnosed or seen as swelling, redness, heat, pain or even loss of certain functions. This is just the signs of acute inflammation. Our bodies are created to fight off anything that may seem to be foreign or not what belongs in our bodies and in return, they will fight and send off responses from it. When our body gets into fight or flight mode, it can either be good or bad. Inflammation also includes many different cells from our immune systems, and they can release many different substances. These substances are known as inflammatory mediators. Inflammation can be good or bad.
Now let's look at wound healing. Wound healing can be described in many ways. It can be primary and even secondary healing. In the end, it mostly means healing of the skin. Wound healing can come from so many different aspects and areas as injuries can occur on so many levels and with all kinds of layers of skin. In order for an organism to survive, they need to have the ability to repair and regenerate themselves. You can classify wound healing occasionally as a primary healing and a secondary healing. Inflammation can play a role in the process of wound healing and unfortunately, only about 15% of wounds will actually heal.
Inflammation and wound healing have their similarities and their differences. When it comes to a wound, our bodies immediate reaction is to start initiating a clotting factor to help protect the injury site from bleeding out. It is natural for our bodies to help trigger a response to let us know that something is not quite okay and that it needs further evaluation. Inflammation is more of a way to help send responses to let us know that something is not okay within our bodies and with wound healing, it is a way for our bodies to heal.
References:
1. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. In brief: What is an inflammation? [Updated 2021 May 18]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279298/Links to an external site.
2. Ozgok Kangal MK, Regan JP. Wound Healing. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK535406/
Hello class, inflammation is an essential, nonspecific and innate immune response that involves the breakdown of tissues and clean-up of cellular, extra-cellular and pathogen debris. Normally, this resolves after one to two weeks when infiltrated leukocytes return to their pre-inflammation numbers and phenotypes (Zhao et al., 2016). However, in the presence of an external stimulus that causes tissue damage, inflammation can become prolonged and heightened, overtime. One example I chose for inflammatory condition is Dermatitis. What is Dermatitis= it's an inflammation of the skin, which is caused by an injury such as cut, bee sting, a bruise or an illness where the immune system mistakenly attacks itself. One example of an infectious disorder from a wound is Impetigo. Impetigo occurs when the skin becomes infected with bacteria, usually staph aureus or staph pyogenes through an insect bite, a cut or other injury.
Compare and contrast the causes, signs and symptoms, diagnostic tools, and treatment.
Contact dermatitis is caused by exposure to a substance that irritates skin or triggers an allergic reaction whereas, Impetigo is caused by bacteria usually staphylococci organisms. Signs and symptoms of contact dermatitis include rashes. They are very itchy and are leathery patches which are hyperpigmented and sometimes with bumps and bruises. Impetigo’s s/s’s includes sores which easily rupture and ooze for a few days and forms crust later. To diagnose dermatitis, doctors start with patch tests and may do biopsy to further rule out other conditions whereas getting physical examination done and gathering history of the patient will help diagnose impetigo. In addition, bacterial culture can be used for confirmation of MRSA if impetigo outbreak is present and possible skin biopsy as well. Treatment for dermatitis includes applying rash cream, exposing to light therapy, using oral corticosteroids and using wet dressing for severe dermatitis (Mayoclinic.org, 2023). Treatment for impetigo topical antibiotics, or systemic antibiotics for cases of bullous and non-bullous impetigo if they have more than five lesions, deep tissue involvement, lymphadenopathy etc (Nardi et al., 2024).
In what ways are they similar and what are they different?
Dermatitis and impetigo are both skin related disorders where the skin becomes inflamed and infected. The causes are infection, bacteria and inflammation. However, the difference is that impetigo is a contagious bacterial infection that often starts from the breaks in the skin whereas dermatitis is exposure to an irritant which causes skin breakdown, rashes and severe cases fluid filled pus.
Reference
Zhao, R., Liang, H., Clarke, E., Jackson, C., & Xue, M. (2016). Inflammation in Chronic Wounds. International journal of molecular sciences, 17(12), 2085. https://doi.org/10.3390/ijms17122085Links to an external site.
Mayo Clinic. (2023). Dermatitis. Mayo Foundation for Medical Education and Research. https://www.mayoclinic.org/diseases-conditions/dermatitis-eczema/diagnosis-treatment/drc-20352386Links to an external site.
Nardi, M, & Schaefer, J. (2023). Impetigo. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK430974/Links to an external site.
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