Module 3 Weekly Note.

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 Module 3 Weekly Note.  

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Module3WeeklyNote_Assignment.docx

Module 3 Weekly Note. Address each heading in the yellow outline note.

Understand the mechanisms of action of psychotropic medications and how they affect neurotransmission.

Read Chapter 3, pages 51-76. No reference needed.

Ligand-Gated Ion Channels as Targets of Psychopharmacological Drug Action 51

Ligand-Gated Ion Channels, Ionotropic Receptors, and Ion-Channel-Linked Receptors 51

Ligand-Gated Ion Channels: Structure and Function 53

Pentameric Subtypes 53

Tetrameric Subtypes 54

The Agonist Spectrum 56

Different States of Ligand-Gated Ion Channels 63

Allosteric Modulation: PAMs and NAMs 64

Voltage-Sensitive Ion Channels as Targets of Psychopharmacological Drug Action 66

Structure and Function 66

VSSCs (Voltage-Sensitive Sodium Channels) 67

VSCCs (Voltage-Sensitive Calcium Channels) 70

Ion Channels and Neurotransmission 73

Summary 76

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