MN 553 unit 9 DQ 1

Unit 9: Unit 9: Complementary and Alternative Medicine (CAMs) and Pharmacogenomics - Discussion 

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Topic: Pharmacogenomics in Primary Care

Explain one of the following statements in your own words. Give an example of implications for you as the prescribing primary care provider. 

1. Carbamazepine has a black box warning recommending      testing for the HLA-B*1502 allele in patients with Asian ancestry prior to      starting therapy. 
2. Testing for CYP2D6 variants prior to starting tamoxifen      for breast cancer. 
3. A genetic variation in how the metabolite of the cancer      drug irinotecan SN-38 is inactivated by the body.