GENETICS Complete all three parts and answer all questions.

 

Student Name

Date

Questions

Student Response

Part I

Original DNA Strand:

3’-T A C C C T T T A G T A G C C A C T-5’

Transcription (base sequence of RNA):

Translation (amino acid sequence):

Mutated gene sequence one:

3’-T A C G C T T T A G T A G C C A T T-5'

Transcription (base sequence of RNA):

Translation (amino acid sequence):

Mutated gene sequence two:

3’-T A A C C T T T A C T A G G C A C T-5’

Transcription (base sequence of RNA):

Translation (amino acid sequence):

What is the significance of the first and last codons of an mRNA transcript?

Explanation:

What meaning do these mRNA codons have for protein synthesis?

Explanation:

Did the two mutations result in a change in the final proteins? If so, describe the change.

Response/ explanation:

In general, why might a change in amino acid sequence affect protein function?

Explanation:

Part II

Punnett Square

1. Chances (%) for healthy child, not a carrier
2. Chances (%) for child that is carrier for cystic fibrosis trait
3. Chances (%) for child with cystic fibrosis

Fill out/adapt Punnett Square:

______

                _____

______

______

1. Chances (%) for healthy child, not a carrier:
2. % for child that is carrier for cystic fibrosis trait:      
3. % for child with cystic fibrosis:      

Part III: Essay

How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?

• Include steps in meiosis that increase variability
• Include the process of fertilization.

Explanation: