Discussion post: Clinical Significance

How does a nurse know what (if any) knowledge in a research study is usable for clinical practice? What would a critical thinker look for in the evidence before deciding to change? What influence do credibility and clinical significance have on your decisions to integrate research-based evidence into your practice?

I need one full page with two references to support the evidence. 

Use the scholarly articles that are less than 5 years published to support the evidence and another one  from the book we are using in the class.

Thank you.