300words discussion

For this paper, provide 1) a concise yet through description of the key question that was addressed by the authors, and 2) a novel question that either the authors did not address but should have, or that occurred to you after having read the paper. This should be a novel insight that might improve the paper's impact, clarify a concept, or address a key/new issue that was not directly addressed in the original discussion paper. Limit ~300 words