3. After the pilot study (described in #2), the main trial is conducted and involves a total of 200 patients ...

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     3. After the pilot study (described in #2), the main trial is   conducted and involves a total of 200 patients. Patients are enrolled and   randomized to receive either the experimental medication or the placebo. The   data shown below are data collected at the end of the study after 6 weeks on   the assigned treatment.         Experimental   (n=100) Placebo (n=100)   %   Hypertensive 14% 22%          Generate a   95% confidence interval for the difference in proportions of patients    with   hypertension between groups.    

    • 8 years ago
    Pooled Proportion, p = (n1 p1 + n2 p2)/(n1 + n2) = (100 * 0.14 + 100 * 0.22)/(100 + 100) = 0.18 ...
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