Genetic Engineering will change everything Forever
Video 1
Humans have been engineering life for thousands of years. True or false?
True
What is the function of DNA and what are its four basic building blocks?
Forms structure for growth and reconstruction, GATC
what was the goal of bombarding plants with radiation in the 1960s?
random mutations at random chance for useful variations
What was the first genetically organism and when was it born?
Mouse, 1974
In 1984, what was the first patent (surrounding genetically engineered organisms) for?
Microbe engineered to absorb oil
What was the first food that was modified?
1994 flavr savr tomato
What is the purpose of CAS9?
Protein cuts invading virus dna and cuts it out
What are some of the diseases that CRISPR could eliminate?
Hiv, herpes, cancer,
Over 3,000 genetic diseases are caused by just one incorrect letter (nucleotide in the DNA sequence.
True or false?
True
Why might some say that NOT using genetic modification in the future is unethical?
Condemns people to suffering and denying them a cure
Two-thirds of the people that die today will die from what?
Age-related causes
There are animals immune to ageing. True or false?
True
CRISPR can never trigger unwanted changes. It is always accurate. True or false?
False
Video 2
CRISPR technology came about from research interested in finding out how bacteria do what?
Eliminate viral dna
Although the CRISPR technology has been used in organisms such as mice and monkeys, it has not yet
been used in human embryos. True or false?
False, Chinese scientist showed this and so did Philadelphia ones
The CRRISPR mechanism acts similarly to vaccines. True or False?
True
Doudna believes that we will see clinical application of CRISPR technology in adults and possibly even
approved therapies by the year 2025 (please note her talk was presented in 2015)
True she does
The role of bio-technology: Enhancing the Future or playing a deadly game?
George church interview
What specific area in human health is George Church's lab working on with CRISPR technology?
Reversing aging
What other areas
Resurrecting extinct animals (wooly mammoth)
Why does Church keep an ethicist on his staff at Harvard? (What type of background do ethicists provide
that other scientist might not have?)
Makes staff think differently (trained in philosophy, humanities, ethics)
What are some of the concerns Church has regarding CRSIPR technology?
Pricing for genetic engineering (reverse engineering only being for rich), designer babies
Under what circumstances does Church feel genetic enhancement is justified?
Why does Church feel that DNA editing is comparable to engineering? (what types of examples does he
provide?) Does Church see a great deal of difference in creating the technology to travel 500 mph on an
airline and editing someone's genes to make them more cognitively more astute?
Example of genetic engineering similar to engineering with moving with cars and jet planes, no he
doesn’t see much difference
How Does Church feel about inherited DNA no longer being our destiny? How does he tie this in with
environment?
Dna was never destiny without environments and roll of dice and vaccination is similar to taking control
over biological destiny,
How might Genetic engineering lead to inequities in society? Would Church 's innovative outlook and
drive in science have been possible if his disabilities had been "edited out" before he was born?
Only rich would be able to afford genetic engineering, discrimination, conflict – no because he has
certain traits that may not be considered good enough
Extinct animal back to life video
We are currently living through the earth's sixth mass extinction called the "Holocene Extinction." What
are the factors that have lead to these mass extinctions?
Deforestation, hunting, climate change, pollution
What percentage of all species might have been lost here on earth?
What percentage of mammals today are also at risk of extinction?
25%
What are the motivations to bring back extinct species?
Biodiversity in an environment
What happens to DNA after an organism has died?
Cells break down, allowing dna to be damaged
How long died after an organism has died, is any remaining DNA viable?
10,000 years
Why is it harder to bring back reptiles and birds then it is mammals?
Mammalian reproduction known much more
What are the three main routes to bring back extinct species and what are the pros and cons of each?
Backbreeding
Pro
Con
Close relative as starting point, really long process, imprecise process
Is it time to question bioengineering?
Is gene editing legal in the U.S?
yes
What are the dangers associated with designer babies?
Social Darwinism, eugenics skyrocketing; designer babies failing, whole group looks bad
According to Knoepfler's talk, the public is well informed on the technology and consequence's of
designer babies in the very near future. True or False?
false
According to Wolpe's talk, what were the three waves of evolution?
Darwinian evolution (passive), civilization (controlling the evolutionary environment), directed evolution
(design)
What are some of the unique species we have already created using genetic engineering?
Beefalo Cow buffalo hybrid, geep goat sheep hybrid, cama camel llama, liger lion tiger, zorse zebra horse
In all species there is just one kind of DNA within all of their cells. True or False?
False, there is dna and mitochondrial dna
We now have computer chips with living neurons operating them. True or false?
true
We do not yet have the technology to develop a cell with a genome that was created by a computer.
True or false?
false
How Technology Changes Culture
The film Gattaca implies that selecting certain genes reduces an individual's propensity for violence,
crime, and other undesirable behaviors. True or false?
True
In the movie, "Gattaca," Freeman's parents express regret over Freeman as a "faith baby". What is a
"faith baby"?
children born without the assistance of reproductive technology
Although in the movie genetic profiling is illegal, how do employers often test potential employees for
their legitimacy as an employee ?
In the film, genetic discrimination for employment is illegal, but often overlooked, and most everyone is
subjected to genetic profiling. Employers often test potential employees for their genetic material, using
blood samples, skin cells, and hair samples.
What do the terms "valids" and in-valids" mean? What term is best used to describe Freeman?
Valids’ are genetically modified in a eugenics lab, made to be the ‘best possible version’ they can be.
Invalids’, ‘god-children’, ‘faith births’ or ‘degenerates’ are birthed naturally without any improvements
made to their DNA. They are susceptible to gene mutations and thus are ‘genetically inferior’, having
weaker health, poorer eyesight and less strength than the genetically modified
Vincent Freeman is born an invalid,
What must Freeman do to land a technical position at Gattaca Aerospace Corporation?
Vincent Freeman borrows the DNA of Jerome Morrow in order to get into Gattaca Aerospace
Corporation and from there, he succeeds purely by his own effort and determination.
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