Zika Global Health APA Style

Editorial

Rev. Eletr. Enf. [Internet]. [cited __/__/__];18:e1136. Available from: http://dx.doi.org/10.5216/ree.v18.39890.

Zika virus epidemic: the newest international emergency

Ruth Minamisava1, Ana Karina Marques Salge2, Thaíla Corrêa Castral3, Sandra Maria Brunini de Souza4,

Romilda Rayane Godoi Souza5, Marília Cordeiro de Sousa6

Infection from the Zika virus is a relatively new disease with

limited publications reporting cases and research on outbreaks. It was

initially described before 2007 in Africa and Asia, then later in the

French Polynesia in the Pacific, and finally in the Americas, in 2015.

Brazil confirmed its first case of infection from the Zika virus in March

2015(1) and since October 2015 it has recorded an explosive growth in

the number of babies born with microcephaly and also an increase in

neurological conditions, including Guillain-Barré syndrome. The strong

suspicion that the infection from the Zika virus is related to these

manifestations is what brought the Public Health Emergency

Committee of the World Health Organization to declare on February 1st

of 2016 that the spread of the virus is an emergency international public

health problem, meaning that it is a serious, unexpected extraordinary

event that could potentially require a coordinated international

action(2-3). The absence of another explanation for the dramatic increase

in cases of microcephaly and the Guillain-Barré syndrome, both

concentrated in areas newly infected by the Zika virus, supports the

recommendation of aggressive measures to prevent and reduce infection with the Zika virus, especially

among pregnant women and those of reproductive age.

In the same document, the World Health Organization recommends monitoring cases of microcephaly

and the Guillain-Barré syndrome in the areas of risk and etiological studies of these events to determine

whether infection by the Zika virus is causal and if there are other risk factors associated. Measures of

additional precautions are as follows:

(i) Related to the transmission of the virus: epidemiological surveillance, vector control,

protection measures, information and counseling for pregnant women and to those who wish

to get pregnant.

1 RN, Ph.D. in Tropical Medicine. Associate Professor at the School of Nursing at the Federal University of Goiás (FEN/UFG) Goiânia, Goiás, Brazil. E-mail: [email protected]. 2 RN, Ph.D. in Pathology. Associate Professor at FEN/UFG. Goiânia, Goiás, Brazil. E-mail: [email protected]. 3 RN, Ph.D. in Health Sciences, Adjunct Professor at FEN/UFG. Goiânia, Goiás, Brazil. E-mail: [email protected]. 4 RN, Ph.D. in Nursing. Associate Professor at FEN/UFG. Goiânia, Goiás, Brazil. E-mail: [email protected]. 5 RN, master’s student at the Graduate Program in Nursing of FEN/UFG. Goiânia, Goiás, Brazil. E-mail: [email protected]. 6 RN, master’s student at the Graduate Program in Nursing of FEN/UFG. Goiânia, Goiás, Brazil. E-mail: [email protected].

Suggested citation: Antunes CMC, Rosa AS, Brêtas ACP. Zika virus epidemic: the newest international emergency. Rev. Eletr. Enf. [Internet]. 2016 [cited __/__/__];18:e1136. Available from: http://dx.doi.org/10.5216/ree.v18.39890.

Minamisava R, Salge AKM, Castral TC, Souza SMB, Souza RRG, Sousa MC.

Rev. Eletr. Enf. [Internet]. [cited __/__/__];18:e1136. Available from: http://dx.doi.org/10.5216/ree.v18.39890.

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(ii) Long-term measures: investment in research for vaccine production, accurate diagnosis and

treatment, training for caring for neurological syndromes and congenital malformations.

(iii) Measures for travelers: counseling, disinfestation of aircrafts and airports.

(iv) Sharing of information.

Some inquiries have been made about the magnitude of this epidemic and its association with

microcephaly and neurological disorders(4-5). It is reasonable to consider that there is an underreporting of

microcephaly in the records of the Live Births Information System in Brazil. It is also to be expected that, after

the national alert, the number of suspected cases would rise. When there is an increase or the

implementation of surveillance, this always results in higher sensitivity of detection of suspected/reported

cases with an increase in false positives. For these reasons, it is possible to say that part of the increase in

reported cases of microcephaly may be attributable to the current intense surveillance. What is

inconceivable, however, is that the prevalence of microcephaly in northeastern Brazil is 10 to 20 times higher

than in other countries(6). At present, there are hypotheses that the Zika virus may have an etiologic and/or

pathophysiological role for these events, which is usually rare.

What seems indisputable is the gravity of the situation. Health managers cannot wait for high-level

scientific evidence. Care and prudence when assessing is advisable, and the same goes for avoiding

premature conclusions. However, given the potential threat, we have a duty to at least protect pregnant

women and their fetuses. The current situation poses many challenges that we need to face and it seems

logical that Brazil take the lead in beginning the actions. We recognize in our history both the success in the

fight against yellow fever early in the last century and also our recent inefficiency in the fight against the

Aedes aegypti mosquito to control dengue and chikungunya. It is necessary to create, renew, and strengthen

our control strategies for an effective protection.

What do we have that is new to envision a better outcome? An international effort, funding for

research to better fight the Zika virus, and mobilization of the population and health professionals

considering the severity of the disease it causes and its consequences. Difficulties? Many, no doubt. In

addition to the vector control difficulties already known in fighting dengue, other mosquitos of the genus

Aedes circulating in Brazil can act as vectors of the Zika virus(7-8), which creates new possibilities for

transmitting and spreading the infection. However, the need for emergency actions is clear, at least to reduce

the impact and the fear of congenital malformations in future generations.

A relentless fight against the mosquito should be the main focus of our actions and this implies in

reviewing our attitudes as citizens. There is no room for mere spectators. The battle has begun and it will be

a long one! It is time to act! It is time for the nation to work together! It is time to call the entire country to

action!

REFERÊNCIAS

1. Zanluca C, Melo VCA, Mosimann ALP, Santos GIV, Santos CND, Luz K. First report of autochthonous transmission of

Minamisava R, Salge AKM, Castral TC, Souza SMB, Souza RRG, Sousa MC.

Rev. Eletr. Enf. [Internet]. [cited __/__/__];18:e1136. Available from: http://dx.doi.org/10.5216/ree.v18.39890.

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Zika virus in Brazil. Mem Inst Oswaldo Cruz [Internet]. 2015 [cited 2016 mar 31];110(4):569-72. Available from: http://dx.doi.org/10.1590/0074-02760150192. 2. World Health Organization [Internet]. Geneva: World Health Organization (SW) [cited 2016 mar 31]. WHO | Zika vírus. Fact sheet. Updated January 2016. Available from: http://www.who.int/mediacentre/factsheets/zika/en/. 3. World Health Organization [Internet]. Geneva: World Health Organization (SW) [cited 2016 mar 31]. Frequently asked questions on IHR Emergency Committee. Available from: http://www.who.int/ihr/procedures/en_ihr_ec_faq.pdf. 4. Butler D. Zika virus: Brazil’s surge in small-headed babies questioned by report. Nature [Internet]. 2016 [cited 2016 mar 31];530(7588):13-4. Available from: http://www.nature.com/doifinder/10.1038/nature.2016.19259. 5. Tetro JA. Zika and microcephaly: causation, correlation, or coincidence? Microbes Infect [Internet]. 2016 [cited 2016 mar 31]. Available from: http://dx.doi.org/10.1016/j.micinf.2015.12.010. [Epub ahead of print]. 6. Schuler-Faccini L, Ribeiro EM, Feitosa IM, et al. Possible Association Between Zika Virus Infection and Microcephaly - Brazil, 2015. MMWR Morb Mortal Wkly Rep [Internet]. 2016 65(3):59-62. Available from: http://dx.doi.org/10.15585/mmwr.mm6503e2. 7. Higgs S. Zika Virus: Emergence and Emergency. Vector-Borne Zoonotic Dis [Internet]. 2016 [acesso em: 23 fev. 2016];16(2):75-6. Available from: http://online.liebertpub.com/doi/10.1089/vbz.2016.29001.hig. 8. Marano G, Pupella S, Vaglio S, Liumbruno GM, Grazzini G. Zika virus and the never-ending story of emerging pathogens and transfusion medicine. Blood Transfus [Internet]. 2015 [acesso em: 23 fev. 2016]. Available from: http://dx.doi.org/10.2450/2015.0066-15. [Epub ahead of print].

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