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Guillain-Barre

ALS (Lou Gehrig’s)

Myasthenia Gravis

What is

This?

Auto-Immune or not?

A PNS disorder, acute inflammatory demyelinating polyneuropathy, rapidly progressing flaccid paralysis.

Auto-immune

Rapidly progressing fatal CNS disease that affects voluntary muscle control, leads to death of the cells resulting in the brain losing the ability to initiate and control muscle movement

Affects the diaphragm and chest wall resulting in respiratory failure and need for placement of an artificial airway and ventilator support, does not impair the senses or ability to think.

Neuromuscular junction disorder that results in the body’s immune system attacking healthy cells

Auto-immune

What are the risk factors/Causes it?

Cause: infection by virus or bacteria usually respiratory or GI

No known cause but environment and genetic plays a role

No known risk factor

How do you Diagnose?

Lumbar puncture to obtain CSF (findings include elevated protein)

Electro myography reveals slowed nerve conduction velocity soon after the patient develop paralysis

Both upper and lower motor neuron damage that cannot be attributed to other causes

Serological test

Electro myography

Edrophonium (Tensilon)- Anticholinesterase

IVP, (Diarrhea, Bradycardia)

Antidote: Atropine

What are the signs and symptoms?

How do you treat?

Nursing Considerations