Epidemiology & Population Hlth
Due March 13
This is a graded discussion: 100 points possible
Due March 13
INTRODUCTION
When you encounter epidemiological studies in peer-reviewed journal articles, how do you evaluate them? Which criteria help to determine preference of one study design over another to investigate a given research question? At this point in your studies, you have likely developed a degree of familiarity with basic epidemiological concepts. The next step in your progress toward becoming a scholar-practitioner involves developing your critical skills—that is, enhancing your ability to review and assess the work of others in the field. Part of this is understanding the research designs and methodologies utilized in research studies.
This module, you examine two important categories of epidemiological study designs: observational and experimental.
What's Happening This Module?
Module 2: Study Designs in Population Research is a 2-week module—Weeks 3 and 4 of the course—in which you will explore study designs in population research. Week 3 focuses on observational designs, and Week 4 focuses on experimental designs.
OBSERVATIONAL STUDY DESIGNS
INTRODUCTION
Consider for a moment the great strides made in treating breast cancer and HIV/AIDS, improvements in perinatal outcomes, and development of a malaria vaccine. These strides toward improving health outcomes are a result of research; research has helped healthcare professionals and others better understand disease and, therefore, offer more effective treatment.
In Week 2, you explored descriptive epidemiological studies, examining the distribution of disease in terms of person, place, and time. This week, you will begin looking at analytic epidemiology designs that focus on the association between an exposure to a risk factor (e.g., radiation, cigarette smoke, poor diet) and the resulting health outcomes. You will examine observational studies, in particular, and consider how and why various observational study designs could be appropriate for a specific health problem and population.
LEARNING OBJECTIVES
· Analyze observational study designs used in analytic epidemiology
· Evaluate the application of observational studies for improving population health status
This is a graded discussion: 100 points possible
Due March 13
Week 3: Discussion
OBSERVATIONAL STUDY DESIGNS
A clinical pediatric nurse has noticed a rise in childhood asthma diagnoses among the Hispanic population served by the local clinic. The nurse is concerned about this increase in asthma incidence in the patient population and turns to the literature to explore current research on this topic. The nurse finds, through the reading, that there appears to be an association between parental smoking and childhood asthma and wonders if this could be the cause of the rise in cases.
This type of suspected association between a risk factor (exposure) and a particular outcome (childhood asthma) can be evaluated using an observational study design. A relevant case-control study would match a group of controls (no asthma) with the case group (asthma diagnosis). Both groups would then be assessed on certain historical exposures like (a) family history; (b) early childhood respiratory infections; (c) secondhand smoke exposure; (d) urban residence (ozone); and (e) obesity. Measures might include interviews, surveys, and medical records. If results show the case group has a higher rate of exposure to a given risk factor, the researcher may conclude that exposure results in greater odds of asthma.
In any epidemiological study, the design and methodology used should be appropriate for that study and for the research question. It is important for researchers to understand the strengths and limitations of each of the study designs and methods. This gives them a better chance of correctly interpreting results and synthesizing them for use in developing and implementing evidence-based population health programs. For this Discussion, you will explore the strengths and limitations of various types of observational study designs and critique their appropriateness for specific studies.
This type of suspected association between a risk factor (exposure) and a particular outcome (childhood asthma) can be evaluated using an observational study design. A relevant case-control study would match a group of controls (no asthma) with the case group (asthma diagnosis). Both groups would then be assessed on certain historical exposures like (a) family history; (b) early childhood respiratory infections; (c) secondhand smoke exposure; (d) urban residence (ozone); and (e) obesity. Measures might include interviews, surveys, and medical records. If results show the case group has a higher rate of exposure to a given risk factor, the researcher may conclude that exposure results in greater odds of asthma.
In any epidemiological study, the design and methodology used should be appropriate for that study and for the research question. It is important for researchers to understand the strengths and limitations of each of the study designs and methods. This gives them a better chance of correctly interpreting results and synthesizing them for use in developing and implementing evidence-based population health programs. For this Discussion, you will explore the strengths and limitations of various types of observational study designs and critique their appropriateness for specific studies.
RESOURCES
Be sure to review the Learning Resources before completing this activity. Click the weekly resources link to access the resources.
LEARNING RESOURCES
Required Readings
·
· Friis, R. H., & Sellers, T. A. (2021). Epidemiology for public health practice (6th ed.). Jones & Bartlett.
. Chapter 6, “Study Designs: Ecologic, Cross-Sectional, Case Control”
. Chapter 7, “Study Designs: Cohort Studies”
· Bahr, R., Clarsen, B., Derman, W., Dvorak, J., Emery, C. A., Finch, C. F., Hägglund, M., Junge, A., Kemp, S., Khan, K. M., Marshall, S. W., Meeuwisse, W., Mountjoy, M., Orchard, J. W., Pluim, B., Quarrie, K. L., Reider, B., Schwellnus, M., Soligard, T., Stokes, K. A., … Chamari, K. (2020). International Olympic Committee consensus statement: methods for recording and reporting of epidemiological data on injury and illness in sport 2020 (including STROBE Extension for Sport Injury and Illness Surveillance (STROBE-SIIS)) Links to an external site. . British Journal of Sports Medicine, 54(7), 372–389. https://doi.org/10.1136/bjsports-2019-101969
· Community Preventative Services Task Force. (n.d.). The community guide Links to an external site. . https://www.thecommunityguide.org/
· Framingham Heart Study. (n.d.). Epidemiological background and design: The Framingham heart study Links to an external site. . https://www.framinghamheartstudy.org/fhs-about/history/epidemiological-background/
· STROBE. (2021). Home Links to an external site. . https://www.strobe-statement.org/ The STROBE Checklist is considered the gold-standard in assessing the quality of observational research studies.
· U.S. Department of Health and Human Services. (n.d.). Healthy People 2030 Links to an external site. . https://health.gov/healthypeople
ARTICLES FOR THIS WEEK’S DISCUSSION:
Note: By Day 1, your Instructor will assign you to a small group. Your group will be assigned two of the following articles to analyze.
· Batty, G. D., & Hamer, M. (2020). Vascular risk factors, Framingham risk score, and COVID-19: Community-based cohort study Links to an external site. . Cardiovascular Research, 116(10), 16641665. https://doi.org/10.1093/cvr/cvaa178
· Hillyer, G. C., Nazareth, M., Lima, S., Schmitt, K. M., Reyes, A., Fleck, E., Schwartz, G. K., & Terry, M. B. (2021). E-cigarette use among young adult patients: The opportunity to intervene on risky lifestyle behaviors to reduce cancer risk Links to an external site. . Journal of Community Health. Advance online publication. https://doi.org/10.1007/s10900-021-01027-7
· Kebede, E., Kekulawala, M. (2021). Risk factors for stillbirth and early neonatal death: A case-control study in tertiary hospitals in Addis Ababa, Ethiopia Links to an external site. . BMC Pregnancy and Childbirth, 21(1), Article 641. https://doi.org/10.1186/s12884-021-04025-8
· Najafpour, Z., Godarzi, Z., Arab, M., & Yaseri, M. (2019). Risk factors for falls in hospital in-patients: A prospective nested case control study Links to an external site. . International Journal of Health Policy and Management, (5), 300–306. https://doi.org/10.15171/ijhpm.2019.11
· Whittle, R. S., Diaz-Artiles, A. (2020). An ecological study of socioeconomic predictors in detection of COVID-19 cases across neighborhoods in New York City Links to an external site. . BMC Medicine, 18(1),Article 271. https://doi.org/10.1186/s12916-020-01731-6
· Spector, A. L., Quinn, K. G., McAuliffe, T. L., DiFranceisco, W., Bendixen, A., Dickson-Gomez, J. (2020). Health-related quality of life and related factors among chronically homeless adults living in different permanent supportive housing models: A cross-sectional study Links to an external site. . Quality of Life Research: An International Journal of Quality-of-Life Aspects of Treatment, Care and Rehabilitation, 29(8), 20512061. https://doi.org/10.1007/s11136-020-02482-w
· Palència, L., Ferrando J., Marí-Dell'Olmo, M., Gotsens, M., Morrison, J., Dzurova, D., Lustigova, M., Costa, C., Rodríguez-Sanz, M., Bosakova, L, Santana, P., & Borrell, C. (2020). Socio-economic inequalities on cancer mortality in nine European areas: The effect of the last economic recession Links to an external site. . Cancer Epidemiology, 69, Article 101827. https://doi.org/10.1016/j.canep.2020.101827
· Nguyen, L. H., Örtqvist, A. K., Cao, Y., Simon, T. G., Roelstraete, B., Song, M., Joshi, A. D., Staller, K., Chan, A. T., Khalili, H., Olén, O., & Ludvigsson, J. F. (2020). Antibiotic use and the development of inflammatory bowel disease: A national case-control study in Sweden Links to an external site. . The Lancet. Gastroenterology & Hepatology, (11), 986–995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034612/
Required Media
· The Challenges of Conducting Trials
Time Estimate: 2 minutes
· Let’s Learn Public Health. (2017, May 5). Epidemiological studies—made easy! [Video]. Links to an external site. YouTube. https://www.youtube.com/watch?v=Jd3gFT0-C4s
Note: The approximate length of this media piece is 10 minutes.
TO PREPARE:
· Review the different types of observational study designs presented in the Learning Resources: ecologic, cross-sectional, case-control, and cohort.
· Carefully examine the characteristics, strengths, and limitations of each design.
· Consider when it is appropriate to use each of the observational study designs.
· Consider how using observational study designs can lead to improvements in population health.
· By Day 1 of this week, you should have received a communication from your Instructor assigning you to a small group to review two specific articles. Review the two articles your group was assigned, with a critical eye toward the researchers’ use of study design and their selected methods. Although several students will be assigned the same articles, this is NOT a group project; please submit your Discussion posts individually. You will then have the opportunity to discuss and share your thoughts with your colleagues.
DISCUSSION Due March 13
Post a brief description of the two studies you were assigned, with a particular focus on the study design and methods. Then:
· Describe at least one strength and one limitation of each study’s design.
· Identify the population, data sources, and epidemiologic measures of association that the authors used.
· Finally, share your insights about the appropriateness of the design for the study. Do you agree with the researchers’ choice of design?
· Do you agree with the researchers’ conclusions? Justify your reasoning.
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NURS_8310_Week3_Discussion_Rubric |
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Criteria |
Ratings |
Pts |
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This criterion is linked to a Learning OutcomeRESPONSIVENESS TO DISCUSSION QUESTION (20 possible points) Discussion post minimum requirements: The original posting must be completed by Day 3 at 10:59 pm CT. Two response postings to two different peer original posts, on two different days, are required by Day 6 at 10:59 pm CT. Faculty member inquiries require responses, which are not included in the peer posts. Your Discussion Board postings should be written in Standard Academic English and follow APA 7 style for format and grammar as closely as possible given the constraints of the online platform. Be sure to support the postings with specific citations from this week's learning resources as well as resources available through the Walden University library and other credible online resources (guidelines, expert opinions etc.) |
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20 pts |
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This criterion is linked to a Learning OutcomeCONTENT REFLECTION and MASTERY: Initial Post (30 possible points) |
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30 pts |
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This criterion is linked to a Learning OutcomeCONTRIBUTION TO THE DISCUSSION: First Response (20 possible points) |
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20 pts |
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This criterion is linked to a Learning OutcomeCONTRIBUTION TO THE DISCUSSION: Second Response (20 possible points) |
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20 pts |
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This criterion is linked to a Learning OutcomeQUALITY OF WRITING (10 possible points) |
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10 pts |
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Total Points: 100 |