Human Disease Lab Series Organization and Chemistry

Human Disease Lab Series

( Systems Affected Metabolic Respiratory Immune Gastrointestinal Somatic Nervous Central Nervous Differential Diagnosis How would Ornithine transcarbamylase (OTC) deficiency , Medium chain acyl-CoA dehydrogenase (MCAD) deficiency and Glutaricaciduria I (GA I) metabolic disorder make diagnosis more difficult? Define your reasoning. )Organization and Chemistry

The Symptoms This rare but serious metabolic condition causes swelling in the liver and brain and has been linked with giving aspirin to children while suffering from viral infections, i.e., most commonly the flu and chickenpox.

Diagnosis

How would you diagnose thismetabolic disease?What clinical diagnostic aids would you utilize in this process and why?

Misdiagnosis With symptoms appearing and progressing rapidly 3-5 days after onset of a viral infection, what key factors would help avoid pinning these symptoms upon the known viral infection?

The Characteristics

Define the major characteristics associated with this metabolicdisease. Demonstrateat least three of these characteristics in a BioDigital Human model.

( Insert BioDigital image of a model associated with a characteristic here . )Characteristic I:

( Treatment Treatment must be prompt to avoid permanent damage . What treatment is utilized for this metabolic disease process and why is time a critical component for survival? Are there varying levels of treatment depending on severity? )

( Insert BioDigital image of a model associated with a characteristic here. )Characteristic II:

( Insert BioDigital image of a model associated with a characteristic here. )Characteristic III:

( Precautions Are there any precautions that can be taken at birth to diagnose and document IEMs? Quiz Me Take this time to learn about the Quiz Me feature within BioDigital as it will be utilized weekly in the course. )Systemic Implications

As mentioned on page 1, this metabolicdisease can affect multiple human systems. List and describe a systemic implication for each of the systems listed above.

MetabolicMechanism This metabolic disease is caused by inborn errors of metabolism (IEMs). Describe the type of IEM that has been theorized to be associated with this syndrome.

Create a Disease Tour

Now fully equipped with extensive knowledge regarding this disease and its associated processes, use the BioDigital Create a Tour feature to tell a compelling medical story. You may use any and/or all information within this lab to tell this medical story and create your BioDigital tour.

References

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