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Topic-Discussion8-SwitchingGenesonandOff.pdf

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Discussion 8 - Switching Genes on

and Off 31 31

8/11/23, 6:32 PM Page 1 of 27

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Directions: After watching the Switching Genes On and Off

(http://video.pbs.org/video/1503825140/)  video and using what you have

learned in this and previous modules in regards to gene expression, post

your thoughts on the video and DNA research. For full credit in this

discussion, please contribute to the discussion in a meaningful way using

scientific language.

Submission: After you have posted your initial post, read and respond to

two or more of your classmates' posts. Be sure to make substantive and

constructive comments (just posting “nice post” doesn’t count). For

example, add something from your own experience, something you’ve read

or seen. If the situation calls for it, feel free to state an opinion, but be sure

to state any points with which you agree and/or those with which you

disagree, as well as your reasons for agreeing or disagreeing.

Grading: This discussion is worth 30 points and will be graded using

the Discussion Rubric. Pease use it as a guide toward successful completion

of this assignment. 

 

https://www.youtube.com/watch?v=oHKsWOqdy5s

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(https://www.youtube.com/watch?v=oHKsWOqdy5s)

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8/11/23, 6:32 PM Page 2 of 27

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Bonni Haber (She/Her) (https://canvas.fscj.edu/courses/71848/users/107427)

Jul 14, 2023

The video for this assignment was honestly really fascinating. Among the

fruit fly species there were

some that had spots on their wings and some that did not have spots on

their wings. The flies without

spots on their wings also didn't dance as much. Scientists found the gene

that codes for the spots on the

wings and called it the, "paintbrush" gene. Both species of flies had the

gene. The scientist in the video

was interested in why both species had the gene but only one species

had spots. So he decided to look

at the 98% of the double helix that didn't code for protein. He found a

slight difference in DNA just outside

of the paintbrush gene. So he decided to take a sample of that DNA and

mix it with a gene that codes for

protein in a jellyfish. Its the gene that makes the jellyfish glow. He then

injected it into the non spotted fly.

Once he did this the non spotted fly had spots that glowed in the dark.

He found that in the 98% part of

the double helix contained switches. These switches where able to turn

certain genes on or off. So in this

8/11/23, 6:32 PM Page 3 of 27

certain genes on or off. So in this

case the fruit flies switch was found to be a mutation that allows them to

turn on or off the gene that

produces spots.

The way the scientist was able to use jellyfish DNA to make a fly have

spots that would glow in the dark

was the wildest part of this video for me. The research they can do with

DNA is really advanced stuff and

interesting but the manipulation of genes is the stuff movies are made

from. I obviously don't think glow

in the dark wings would benefit a fly in any way but the fact that someone

can essentually engineer a

living creatures genetic makeup to do things so wild is fascination and a

little bit scary.

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Jomer Ibarreta (https://canvas.fscj.edu/courses/71848/users/26650)

Jul 17, 2023

8/11/23, 6:32 PM Page 4 of 27

Great discussion, Boni. I would like to add that gene editing or being

able to turn genes on and off is a powerful tool. Scientists can use

this technology to study how certain genes affect animals. It has a

wide range of uses in medical research. For example, it can be used

to study how certain diseases affect the body or to make animal

models for trying drugs and treatments. This technology can also be

used to give organisms new features, like the ability to fight off

diseases, or even to make whole new organisms. By turning genes on

and off, scientists can control the genetic makeup of animals in a way

that has never been done before. This is very exciting for the future of

biotechnology.

Reference:

"Gene Switching." Genetics Home Reference, U.S. National Library of

Medicine, 8 Mar. 2021,

ghr.nlm.nih.gov/primer/genomicresearch/geneswitch.

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Ashley Burris (https://canvas.fscj.edu/courses/71848/users/142506)

Jul 18, 2023

8/11/23, 6:32 PM Page 5 of 27

Hi Boni! 

I absolutely agree with you, it is scary but also interesting how things

are able to be manipulated in labs. I always wonder about things that

we have now that we don't take a second thought about, I wonder

how much of it was created in a lab or morphed between two animals

etc. It was also interesting to me as well that the flies without the

spots didn't dance as much. I wonder if that was a coincidence or a

direct correlation in some way. 

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Robin Patterson (https://canvas.fscj.edu/courses/71848/users/148704)

Jul 22, 2023

Hi Bonnie,

I learned while reading in Chapter 10 of our textbook today that

altering DNA is not new and that it has been used for over 10,000

years in crops and farm animals. The big debate is when it comes to

altering humans. I am not sure how I feel about this topic either and

would only be more comfortable with the topic with a vast amount of

research. It is fascinating however that in this video clip they were

able to fluoresce the wings of that fly.

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Heidi Street (She/Her) (https://canvas.fscj.edu/courses/71848/users/136481)

Aug 2, 2023

8/11/23, 6:32 PM Page 6 of 27

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Bonnie,

Like you, I was blown away by the injection of jellyfish DNA into the

fly. It really got me thinking about what in the heck else we can inject

DNA into, and what kind of public health advantages can emerge

from this type of research.

I agree, its the stuff movies are made from!

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Jomer Ibarreta (https://canvas.fscj.edu/courses/71848/users/26650)

Jul 17, 2023

Researchers now know more about how genes are controlled because

they can turn genes on and off especially in Drosophila flies. It was

exciting to see how a "glowing" gene from a jellyfish make the black spot

gene shine in the experimental fruit fly. The scientists were able to make

a black-spotted fly to light up in the dark. Scientists can turn genes on

and off by targeting and changing specific sequences of DNA using a

method called CRISPR/Cas9. With this technology, scientists have been

able to study how different amounts of gene expression affect the fruit

flies and how these changes affect the way the organism works.

Scientists have also been able to study how environmental cues affect

how genes are turned on and off in these animals by using gene transfer.

8/11/23, 6:32 PM Page 7 of 27

Researchers can learn more about how genes are controlled with the

help of this technology. The ability to turn on and off DNA genes is a

powerful tool that has changed the way science is done. Researchers can

study the effects of gene expression, come up with new ways to treat

genetic diseases, and even make new organisms and life forms because

they can change genes. In short, being able to turn genes on and off

gives scientists a powerful way to learn more about the complicated

genetic networks that affect life. This helps us learn more about how

diseases start and can lead to new treatments and medicines for a wide

range of conditions, especially genetic disorders.

References:

"CRISPR/Cas9 Genome Editing: What Is It and What Can It Do? | HHMI

BioInteractive." BioInteractive, 24 Jan. 2018,

www.biointeractive.org/classroom-resources/crisprcas9-genome-editing-

what-is-it-and-what-can-it-do.

Komor, Adrienne C., et al. "Programmable editing of a target base in

genomic DNA without double-stranded DNA cleavage." Nature 533.7603

(2016): 420-424.

"Switching DNA Genes On and Off: Benefits in Science." National Center

for Biotechnology Information, U.S. National Library of Medicine,

www.ncbi.nlm.nih.gov/pmc/articles/PMC2904656/

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Ashley Burris (https://canvas.fscj.edu/courses/71848/users/142506)

Jul 18, 2023

8/11/23, 6:32 PM Page 8 of 27

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Hi Jomer! 

The switches were such a profound idea to me. I enjoyed how you

continued to investigate and shed more light on how important they

are and the things they can be manipulated to achieve. Any aid in

studying and developing new treatments for genetic disorders is a

great step in advancement in our society. 

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Tiara Taylor (https://canvas.fscj.edu/courses/71848/users/13719)

Jul 24, 2023

Hi Jomer, 

 

Great job mentioning scientists can turn genes on and off by

targeting and changing specific sequences of DNA using a method

called CRISPR/Cas9. It's really amazing to know that scientists are

being able to find key components in what makes animals/insects be

different or go through certain changes as they evolve and what is

causing them to evolve. Hopefully, by scientists being able to turn on

and off genes, it can then be done in regards to diseases (genetic

wise), and other matters that we don't really having a clear

understanding of. Amazing post!

8/11/23, 6:32 PM Page 9 of 27

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Ashley Burris (https://canvas.fscj.edu/courses/71848/users/142506)

Jul 18, 2023

This was a very interesting video clip, was anyone else intrigued by the

background music they chose? Very Suspenseful! It is shocking to know

that only 2% is being utilized for coding in such a big system. Even more

interesting is that it was found that both had the paintbrush gene but

only one produced spots. That immediately started to get my wheels

turning on how that is even possible. The thought of switches in the DNA

is very mind-blowing to me, the complexity that genes have the ability to

switch on and off seems impossible in theory, but that just goes to show

you how impressive the makeup of bodily structure is. 

 

Side Note, how cool would it be if flies actually had glow-in-the-dark

wings? I have always wanted to see a firefly and that was my first

thought, I just found that super cool!

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Bonni Haber (She/Her) (https://canvas.fscj.edu/courses/71848/users/107427)

Jul 19, 2023

8/11/23, 6:32 PM Page 10 of 27

Ashley, I did notice the music! Interesting! I too am so fascinated at

the complexity of genes and thought the switches were another part

of our makeup that blows my mind! I'm glad I'm not the only one

totally blown away at all of this! Nice post! 

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Robin Patterson (https://canvas.fscj.edu/courses/71848/users/148704)

Jul 21, 2023

Hi Ashley,

I did not realize from the video but after doing more research I

discovered that multiple switches can be next to a gene. Thus

different switches can be active at different time during development.

Also, the different switches can be activated with different cells. 

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Corbin Miller (https://canvas.fscj.edu/courses/71848/users/54253)

Jul 22, 2023

Hello Ashley,

I agree that it is cool that they added DNA from Jellyfish to make the

wings glow to help show the evidence of the experiment working. I

also agree that it is crazy to think about how there are switches and

how they decide whether or not to let specific genes show.

Great discussion!

8/11/23, 6:32 PM Page 11 of 27

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Amira Betancourt (She/Her) (https://canvas.fscj.edu/courses/71848/users/102878)

Jul 24, 2023

Hi Ashley,

I totally agree with you, the jellyfish experiment was super cool. Same

as you, I'm really interested in the science of genes and DNA.

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Heidi Street (She/Her) (https://canvas.fscj.edu/courses/71848/users/136481)

Aug 2, 2023

8/11/23, 6:32 PM Page 12 of 27

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Ashley,

The glowing wings after the jellyfish experiment was very cool! It

reminded me of fireflies!

After reading your comment I had to go back a watch the video

again, this time paying extra attention the background music. Its so

dramatic and I laughed thinking it sounds life the music from the

Twilight Zone! I could definitely see them making an episode based

on gene mutations and exaggerated evolution.

Related but unrelated: When I was little, I remember watching an

episode of the twilight zone where the sun was quickly overheating

the earth over the course of a day. Its actually based on climate

change! Pretty freaky!

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Robin Patterson (https://canvas.fscj.edu/courses/71848/users/148704)

Jul 18, 2023

8/11/23, 6:32 PM Page 13 of 27

The video was on fruit flies where males have spots on their wings.

However, in some species the males do not have spots on their wings.

The presenter knew the code for what he called the paint brush gene

which was the male fruit fly with the spots. When he compared the genes

of the two species, they both carried the gene for the spots although it

was only visible on one of the species' wings. They both have the

capability but only one of the species uses the gene. He used the large

part of the DNA code known as “junk” which is 98% to look for answers.

The area used was just outside of the paint brush gene in the spotted fly

and put it in the unspotted fly with a glowing protein from jellyfish. The

result was that the unspotted fly developed glowing spots. Switches do

not make genes for other areas like hair or muscle, but they turn on or

turn off the genes that do. In the case of the fruit fly it was revealed to be

a mutation. The fact that only 2% of our DNA codes and the other 98%

contain some switches for turning other genes on or off at different times

and for different lengths of time is fascinating. It also makes it apparent

that scientists can manipulate genes for tests or desired effects which

could be useful in future developments. 

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Bonni Haber (She/Her) (https://canvas.fscj.edu/courses/71848/users/107427)

Jul 19, 2023

8/11/23, 6:32 PM Page 14 of 27

Robin, great point and observation that scientists could be using this

manipulation for future developments. It makes me wonder how

much of this is already happening and how much of this could help

change the lives of people who pass down genetic mutations to their

children. I hope we continue to use this science to advance medical

treatments and bettering the quality of life of any we can! Great post. 

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Corbin Miller (https://canvas.fscj.edu/courses/71848/users/54253)

Jul 22, 2023

Edited by Corbin Miller (https://canvas.fscj.edu/courses/71848/users/54253) on Jul 22 at 9:09pm

Hello Robin,

I agree that this video helps give evidence that gene altering science

is going to be apart of the future, just makes you think how it will be

used and if there maybe any reproductions to these actions. It is

crazy to think that 98% of the DNA was overlooked yet the answer to

the question at hand was in the 98%.

Great discussion!

 

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Amira Betancourt (She/Her) (https://canvas.fscj.edu/courses/71848/users/102878)

Jul 24, 2023

8/11/23, 6:32 PM Page 15 of 27

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Hey Robin,

I was also talking about how DNA altering could be used to cure

certain illnesses, and I'm hoping more research goes into it!

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Beyonce Miranda-Gomez (She/Her) (https://canvas.fscj.edu/courses/71848/users/129249)

Jul 25, 2023

Hello Robin, you have clearly fulfilled a clear understanding in the

research topic, well done! Your explanation was clear and also

confirmed my thoughts as well. I am still shocked the by DNA

percentage fact, ONLY 2%!!!!!! With only two percent known, this

opens the doors of the genetic research world into a bigger and

unknown region. Who knows what can happen now with this small

research on FRUIT FLIES!

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Corbin Miller (https://canvas.fscj.edu/courses/71848/users/54253)

Jul 22, 2023

8/11/23, 6:32 PM Page 16 of 27

The video was a great glimpse into the technology of altering DNA and

genes in something as simple as fruit flies. It makes you wonder if that

now that this fruit fly has been adjusted to have its "paint brush" gene

show out that future generations from this specific fly will have their

spots on their wings. Adding to that it is shown that even though the

98% of DNA that was thought to be junk arguably can hold more in it

than previously thought. With this evidence of this "switch" section of the

DNA, does this open new doors to understanding a way to alter the rest

to help out with possible DNA defects that cause health issues. Could

this also open the doors to modifying DNA for helping venerable species

that struggle to survive in an ever changing world?

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Tiara Taylor (https://canvas.fscj.edu/courses/71848/users/13719)

Jul 24, 2023

Hi Corbin, 

 

This video was extremely fascinating in regards to the spots on fruit

flies. What made it even better was breaking down how and how

some have spots and some do not. It also makes you wonder how

many different species of animals and insects differ when being a

male or female. In some cases, it's often the female with unique traits

that stand out and the male lacking those traits or not big in size. It

does seem if scientist are able to determine factors in regards to

animals, and insects, then they just might be able to apply this

research to a certain degree to help humans and change how we can

detect illnesses and disorders. Nice post. 

8/11/23, 6:32 PM Page 17 of 27

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Alexis Clements (https://canvas.fscj.edu/courses/71848/users/137316)

Jul 26, 2023

Edited by Alexis Clements (https://canvas.fscj.edu/courses/71848/users/137316) on Jul 26 at

6:35pm

Hey Corbin,

Thank you for your contribution to this discussion board. You brought

up an amazing point one that I had not even thought about. Could

this fruit fly, with this newly activated "paint brush" gene,  now

reproduce fruit flies with spots as well? Could injecting enough fruit

flies with this gene and releasing them into the wild now cause a

decrease in the amount of fruit flies with no spots? The only thing the

video did not discuss was long-term effects of injecting this fruit fly

with this gene that it had not previously had. Great response and

great observations of the video,

(https://canvas.fscj.edu/courses/71848/users/13719)Tiara Taylor (https://canvas.fscj.edu/courses/71848/users/13719)

Jul 24, 2023

8/11/23, 6:32 PM Page 18 of 27

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The wing mutation in fruit flies is a change in the DNA that causes the

fruit fly to have different wing markings. One of the most common wing

mutations is the "spotted" mutation, which causes the fruit fly to have

black spots on its wings. This mutation is caused by a change in a gene

called the "paintbrush gene." The paintbrush gene is responsible for the

production of a protein that helps to create the black spots on the wings

of the fruit fly. 

Other wing mutations in fruit flies can cause the fruit fly to have shorter

wings, longer wings, or even no wings at all. The wing mutation in fruit

flies is a good example of how "junk" DNA can play a role in evolution.

"Junk" DNA is a term that was once used to describe regions of DNA that

did not appear to have any function. Now, scientists have since learned

that "junk" DNA is essential for many important biological processes. The

paintbrush gene is in a region of DNA that was once thought to be "junk"

DNA. Scientists have now discovered that this region of DNA contains

regulatory sequences that control the expression of the paintbrush gene.

These regulatory sequences can be switched on or off, which can affect if

the fruit fly will have wing spots or not. 

The video was a nice example of how evolution can work. By changing

the expression of genes, even slight changes in DNA can lead to

substantial changes in the appearance of an organism. Like the saying,

small steps will lead to bigger steps.

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8/11/23, 6:32 PM Page 19 of 27

Amira Betancourt (She/Her) (https://canvas.fscj.edu/courses/71848/users/102878)

Jul 24, 2023

This video was very informative and thought-provoking. From this

glimpse into DNA-altering technology, we saw that a species as simple

as fruit flies opened the door for such an interesting conversation. The

scientist found a gene named the "paintbrush gene", which caused some

of the flies to have spots. Since the scientist was confused as to why

some of the flies had spots even though both species had the gene, he

did some experimenting and found a mutation that allowed the flies to

switch the gene on and off. This discovery I feel could aid in finding

cures for certain illnesses.

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Beyonce Miranda-Gomez (She/Her) (https://canvas.fscj.edu/courses/71848/users/129249)

Jul 25, 2023

Hello Amira, I agree! This "small" research leads to deeper

conversations about and other bigger questions which leads to

bigger answers. It's like a recurring circle that keeps going around

but every time it loops around it gets bigger. Truly enlightening!

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Alexis Clements (https://canvas.fscj.edu/courses/71848/users/137316)

8/11/23, 6:32 PM Page 20 of 27

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Jul 26, 2023

Hey Amira,

Thank you for your contribution to this discussion board. I agree with

you this video we definitely thought-provoking especially for it to only

have been about 5 minutes long. I don't know if "confused" would

necessarily be the word I would use to describe the interest in the

difference. He was more so intrigued and/or curious as to what could

be causing this minor difference in such similar species. However,

your recap of the video was right on point and I enjoyed reading your

response. 

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Beyonce Miranda-Gomez (She/Her) (https://canvas.fscj.edu/courses/71848/users/129249)

Jul 25, 2023

There is a reason why scientific research is so important and heavily

studied, it is because of questions and discoveries from the video. In just

5 minutes, we are introduced to new species, surprising facts, new genes

or pieces of DNA, and much more. In just 5 minutes, which I am sure

took a lot more than 5 minutes for Carroll, we learned more about DNA

through one small scientific question. This is why scientific researches

are important, one question can and will lead to multiple answers. In this

8/11/23, 6:32 PM Page 21 of 27

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are important, one question can and will lead to multiple answers. In this

case, the spotted and non-spotted fruit flies were in question, what

makes some of them have or not have these spots. This lead to 3 general

steps: compare, discover, and test. In the discover portion of Carroll's

research there was a surprising fact, 98% of the double helix does not

code for proteins, no one really knows what it does. Meaning, only 2% of

our DNA is known, only 2% of our DNA is responsible of making us who

we are, ONLY 2%!!! Imagine what the rest of the 98% can do! This alone

leads to more questions of the unknown. In the end, Carroll found a piece

of DNA, not a gene (which also blows my mind in itself cause how can

DNA not be a gene,) that switches certain aspects of the actualy genes

on or off. In the end, I am left with this question, what enables the on or

off switch? What makes it go on and what makes it decide to turn on?

This is why scientific research will always be recurring and important,

there is so much to learn and so much to question. Some might question

why we need to know this about fruit flies. To answer, firstly, I question if

humans have a switch gene, if so, this in itself does a lot for our future

understanding. Secondly, I want to introduce you all to the case of

Dengue fever. It is a worldwide endemic which is fatal to some and minor

to others. It was a research in our past writing assignment. It is also

similar to the question of spots and no spots, these questions are

different in important but both correlate in finding answers. It was found

that the mixture of different Dengue fever forms makes people react

severely and die. This answer was found while looking in the same

"genetic machinery" in which Carroll found his own answer. So, in

science, questions lead to answers but they also lead to bigger questions

and bigger answers. Answers that can change the world. 

8/11/23, 6:32 PM Page 22 of 27

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Alexis Clements (https://canvas.fscj.edu/courses/71848/users/137316)

Jul 26, 2023

Through watching the video, the focus was on fruit flies and how one

species has a trait that another species does not. There are two species

of fruit flies, one which has spots on its wings and another with no spots

on its wings. Research was conducted to determine what gene caused

the difference between fruit flies, and what was in the DNA of the spotted

wing fruit flies that the other fruit flies did not have. Through this

research it was found that both species of fruit flies carried the gene that

caused the wing spots, this gene was known as the paint brush gene.

How could both species carry the gene but only some exhibit the

physical trait? This was the question that needed to be answered. Further

research was conducted through the DNA of the spotted wing fruit flies

and regular wing fruit flies  for difference. It was found that there was a

difference in their DNA. The spotted wing fruit flies carried a gene known

as the "Switch"  gene which essentially activated the "Paint brush" gene

and allowed them to exhibit spots. To prove this theory the fruit flies with

no spots were injected with the gene known as the" Switch" gene, and

from this action their "Paint Brush" gene was now activated and they now

exhibit the same trait as the other flies. This video was extremely

interesting and through this research we learned that just because a

species does not exhibit a trait does not mean they do not have the gene

that causes the trait. Learning switch genes showed us that some traits

have to be activated, even though they are already possessed.

8/11/23, 6:32 PM Page 23 of 27

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Heidi Street (She/Her) (https://canvas.fscj.edu/courses/71848/users/136481)

Aug 2, 2023

The video reviews research into the disparity in wing spots between two

closely related fruit fly species. The video highlights that despite sharing

a specific gene responsible for this trait, its manifestation hinges on

gene activation. This activation is orchestrated by an enhancer, a

segment of noncoding DNA once deemed insignificant, now recognized

as a pivotal "switch."

The two closely related fruit fly species share a paintbrush gene

accountable for their coloration, yet each possesses distinct regulatory

switches governing its utilization. One fly species utilizes the paintbrush

gene for wing spots, while the other does not. This discrepancy is

contingent upon how the gene is managed during their development.

The video posits that evolution doesn't hinge on generating new genes;

rather, it ensues through mutations altering switches to elicit functions

from existing genes. With the addition or removal of gene switches, new

variations emerge. As these traits are transmitted to successive

generations, it leads to the eventual formation of new species.

8/11/23, 6:32 PM Page 24 of 27

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(https://canvas.fscj.edu/courses/71848/users/113155)Cori Perry (https://canvas.fscj.edu/courses/71848/users/113155)

Sunday

I honestly wished this video could have lasted longer. I found everything

about it so interesting way scientists can maneuver genes to make

something exactly how they want it... mind-blowing. To be able to

discover "switches" just by studying fruit flies is a phenomenal feat. The 2

flies had identical genes for the spots on the wings, the paintbrush gene,

however only one had the spots. upon further investigation, they

discovered another stretch of DNA that was different in the fly with wing

spots. Once they injected the same stretch of DNA into the unspotted fly,

along with some glowing jellyfish DNA, the spots appeared, and glowed.

They discovered that these sets of DNA are called switches and they

allow animals to use different parts of DNA. 

(https://canvas.fscj.edu/courses/71848/users/137133)

Claudia Huerta (https://canvas.fscj.edu/courses/71848/users/137133)

12:30pm

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The “Switching Genes On and Off (http://video.pbs.org/video/1503825140/)  “ video provides a valuable overview of gene expression and the mechanisms by which genes are switched on and off in cells. It highlights the importance of gene regulation in controlling cellular processes and determining cell fate and function.

One key concept discussed in the video is the role of transcription factors in gene regulation. Transcription factors are proteins that bind to specific DNA sequences and can either activate or repress gene expression. By binding to promoter regions of genes, transcription factors can recruit other proteins and enzymes to either enhance or inhibit the initiation of transcription. This dynamic process allows cells to respond to various internal and external cues and adjust gene expression accordingly.

The video also introduces the concept of epigenetics, which refers to heritable changes in gene expression without alterations to the DNA sequence itself. Epigenetic modifications, such as DNA methylation and histone modifications, can act as "on" or "off" switches for genes. These modifications can be influenced by environmental factors and can have long-lasting effects on gene expression patterns, potentially impacting an individual's health and development.

In terms of DNA research, understanding the mechanisms of gene regulation is crucial for advancing our knowledge of biology and human health. Researchers are actively studying the intricate regulatory networks that control gene expression, aiming to unravel the complexity of cellular processes and identify potential therapeutic targets.

Additionally, the video highlights the potential applications of this knowledge in the field of synthetic biology. By manipulating gene expression and designing synthetic DNA sequences, scientists can engineer cells with desired functions or produce specific gene products for medical and industrial purposes. This emerging field holds promise for advancements in

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industrial purposes. This emerging field holds promise for advancements in medicine, biotechnology, and agriculture.

In conclusion, the "Switching Genes On and Off" video provides a comprehensive introduction to the mechanisms of gene expression and regulation. It emphasizes the central role of transcription factors and epigenetic modifications in controlling gene activity. Understanding these processes is crucial for DNA research, as it allows us to unravel the intricacies of cellular functions and explore applications in synthetic biology.

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