music reading report
Topical Review Article
The Efficacy of Yoga as a Form of Treatment for Depression
Ledetra Bridges, LMSW 1
and Manoj Sharma, MBBS, MCHES, PhD 1
Abstract The purpose of this article was to systematically review yoga interventions aimed at improving depressive symptoms. A total of 23 interventions published between 2011 and May 2016 were evaluated in this review. Three study designs were used: randomized control trials, quasi-experimental, and pretest/posttest, with majority being randomized control trials. Most of the studies were in the United States. Various yoga schools were used, with the most common being Hatha yoga. The number of participants par- ticipating in the studies ranged from 14 to 136, implying that most studies had a small sample. The duration of the intervention period varied greatly, with the majority being 6 weeks or longer. Limitations of the interventions involved the small sample sizes used by the majority of the studies, most studies examining the short-term effect of yoga for depression, and the nonutilization of behavioral theories. Despite the limitations, it can be concluded that the yoga interventions were effective in reducing depression.
Keywords yoga, depression
Received June 7, 2016. Received revised March 10, 2017. Accepted for publication May 19, 2017.
Depression is one of the most common mental illnesses in the
world. It is estimated that there are 350 million people world-
wide who have some form of depression. 1
In the United States,
16 million people had a depressive episode in the past year. 2
A
condition affecting one’s mood and action, depression can
affect one’s life substantially. According to the most recent
World Health Organization, depression is the leading cause
of disability worldwide and is believed to be a major contribu-
tor to the overall global burden of disease. 1
The Diagnostic and Statistical Manual of Mental Disorder,
Fifth Edition, has defined depression as 5 or more of the
following symptoms that are present for 2 or more weeks and
cause significant emotional distress and/or impairment in
functioning. Symptoms are depressed or sad mood, short-
tempered or easily annoyed, loss of interest or enjoyment in
hobbies or activities that was previously enjoyed, feeling of
worthlessness or guilt, thoughts of death or suicide, difficulty
with concentrating or making decisions, feeling tired or fati-
gue, feeling restless or slow, changes in appetite such as over-
eating or loss of appetite, changes in weight such as weight
loss or weight gain, and changes in sleep pattern. 3
According
to the National Institute of Mental Health, depression occurs
due to a combination of genetic, biological, environmental,
and psychological factors. 4
Treatment for depression consists
of participation in psychotherapy, taking antidepressants, or a
combination of both. However, many individuals do not par-
ticipate in psychotherapy or antidepressants due to factors
such as unmet needs, side effects, lack of access/resource, and
personal choice.
Currently, researchers are studying the efficacy and effec-
tiveness of mind-body interventions such as yoga as an alter-
native and complementary treatment for depression. Yoga,
with its origin in ancient India, is recognized as a form of
alternative medicine that implements mind-body practices. The
philosophy of yoga is based on 8 limbs that are better described
as ethical principles for meaningful and purposeful living. 5
While there is no specific definition, yoga has been interpreted
as a process of uniting the body via mind and spirit to promote
physical and mental wellness.
Yoga practices can utilize any or all the 8 limbs. They
generally involve relaxation (shava asana), physical postures
1 Jackson State University, Jackson, MS, USA
Corresponding Author:
Manoj Sharma, MBBS, MCHES, PhD, School of Public Health, Jackson State
University, 350 West Woodrow Wilson Avenue, Jackson, MS 39213, USA.
Email: [email protected]
Journal of Evidence-Based Complementary & Alternative Medicine 2017, Vol. 22(4) 1017-1028 ª The Author(s) 2017 Reprints and permission: sagepub.com/journalsPermissions.nav DOI: 10.1177/2156587217715927 journals.sagepub.com/home/cam
Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
(asana), breathing regulation techniques (pranayama), and
meditation (dhyana). While there are different schools of yoga,
some common schools include Ananda, Anusara, Ashtanga,
Bikram, Iyengar, Integral, Kundalani, Kripalu, Power, Prana,
Sivananda, and Vinyasa. Types of yoga include alignment-
oriented yoga, fitness yoga, flow yoga, gentle yoga, hot yoga,
specialty yoga, and spiritual-oriented yoga.
There have been some known benefits of yoga. Per Woo-
dard, 5
yoga improves flexibility, can loosen muscles resulting
in reduced aches and pain, generates balanced energy, reduces
breathing and heart rates, lowers blood pressure and cortisol
levels, increase blood flow, and reduces stress and anxiety due
to calmness. Yoga practices can thus improve preexisting med-
ical conditions such as arthritis, cancer, mental illness symp-
toms, and so on.
There is a body of research supporting the use of yoga to
reduce depression or depressive symptoms. Mehta and
Sharma 6
published a systematic review of literature on yoga
and depression, searching research articles in English from
2005 to June 2010. They reviewed 18 studies describing the
extent to which yoga has been found to be beneficial as a
complementary therapy for depression and depressive symp-
toms. The purpose of this review was to identify newer studies
after 2011 and ascertain the efficacy of yoga on depression.
Based on this review, recommendations for future interven-
tions have been developed.
Methodology
An extensive literature search was conducted to collect studies for
inclusion in this review. Studies were identified through electronic
database searches of Cumulative Index to Nursing and Allied Health
Literature (CINAHL), Google Scholar, Education Resource Informa-
tion Center (ERIC), PsycINFO, and Medline for the time periods of
2011 to May 2016. Keywords (as title and abstract words used to search
for articles) were yoga and depression/depressive disorder, yoga for
depression/depressive disorder, and treating depression through yoga,
yielding 731 articles. There were 138 records after duplicates were
removed from the search results. One hundred and thirty-eight arti-
cles were screened for intervention. Of those 138 articles, 75 articles
were omitted due to not having an intervention or utilizing interven-
tions that did not target depression (n ¼ 42), and consisting of review and discussion articles (n ¼ 16), or studies still in progress (n ¼ 5). The remaining 63 articles were screened using the inclusion and
exclusion criteria. Inclusion criteria for studies in this review were
the following: (1) publications between 2011 and 2015, (2) publica-
tions in the English language, (3) publication of studies that mea-
sured depression or depressive symptoms as an outcome (see Table 1
for outcome measures of each study), (4) publications of studies that
used yoga as an intervention that included the use of one or more of
the 8 limbs, and (5) studies that used a randomized controlled design
or quasi-experimental or pretest/posttest design.
The exclusion criteria were the following: (1) studies that did not
measure depression or depressive symptoms as an outcome; (2) stud-
ies that were incomplete or ongoing; (3) articles that were published
in a journal not indexed in any of the following databases: CINAHL,
Google Scholar, ERIC, PsycINFO, and Medline; and (4) qualitative
studies. Both authors evaluated the articles. After reading and
reviewing the articles, there were 23 studies included in the systema-
tic review. This is further illustrated in Figure 1. PRISMA guidelines
were followed in selection of these articles for inclusion in this
systematic review. Important components of each study that will
be reviewed include original reference, country of the study, the
name and a brief description of the intervention, duration of the
intervention, age of participants, time of assessments, design and
sample, and salient findings.
Results
A total of 23 studies describing interventions that used yoga as a
form of treatment for depression, meeting the inclusion criteria,
were found through literature search. These studies are described
sequentially, in order of their publication by year in Table 2.
Studies were carried out in Australia, 8,29
India, 10,17,18,28
Iran, 7,16
Italy, 26
Taiwan, 22
the United Kingdom, 21
and the United
States. 9,11-15,19,20,23-25,27
Studies focused on the meditative
aspects of yoga while others incorporated exercise and/or gentle
and slow movements and awareness. Types of yoga included
Antenatal, 21
Anusara, 22
combination of Asana and Pra-
nayama, 10,18,23
Hatha, 8,13,19,20
integrated yoga, 17,28
Iyengar, 14
Kirtan Kriya, 15,26
Mindfulness-based meditation (with
yoga), 9,11,27
Tai chi (with yoga), 12
unspecified, 7,16
and
Viniyoga. 24-25,29
Hatha yoga was used most often (4 times)
among the aforementioned interventions. The next most com-
monly used interventions were Asanas and Pranayama, the
mindfulness-based meditation (with yoga), and Viniyoga, which
were each used thrice.
Participants in the studies were all adults. Many of the studies
reported that the participants were age 18 and older. 8,9,13,19-23,29
Other studies reported that participants were between the ages of
18 and 45, 12,17,23,24
18 and 60, 10,11,16,18,26,27
18 and 80, 14
20 and
35, 7,17
20 and 70, 22,26
30 and 70, 28
and 45 and 90. 15
Participants
in the studies included pregnant women, 9,12,17,19,21,23,25
individ-
uals with a depression diagnosis, 13,16,20,29
cancer patients, 22,28
narcotic drug addicts, 7
patients with poststroke hemiparesis, 8
patients with lower back pain, 10
college students, 11
patients with
atrial fibrillation, 14
caregivers, 15,18
postpartum women, 24
anxiety, 26
and low-income patients. 27
Only one study included patients with a Diagnostic and
Statistical Manual of Mental Disorders, Fourth Edition, diag-
nosis of a depressive disorder. 26
Fourteen studies included
adults with elevated levels of depression diagnosed by Beck’s
Depression Inventory-II, 7
Edinburgh Postnatal Depression
Scale, 9
Structural Clinical Interview for Depression, 12,15,25
MINI-International Neuropsychiatric Interview, 13,20
Hamilton
Depression Rating Scale, 16
Patient Health Questionnaire, 23,24
Depression Anxiety Stress Scale, 29
and a clinician. 10,14,27
Five
studies included patients with self-report of depression. 8,19,21-22,28
In 2 studies, the depression criteria were unclear. 17-18
Studies used pretest/posttest, 12,14,16,26
quasi-
experimental, 9,11,23,27
and randomized controlled
trials. 7,8,10,13,15,17-22,24,25,28,29
Sample sizes were small, ranging
in size from 14 to 136 patients. Intervention periods ranged in
length from 1 week to 24 weeks. One study did not specify its
1018 Journal of Evidence-Based Complementary & Alternative Medicine 22(4)
length, but it can possibly be concluded that it took place for up
to 32 weeks. Among the yoga intervention, participants were
encouraged or required to attend yoga classes anywhere from
once a week to daily for 1 or more weeks. The time asked to
practice yoga ranged from 12 minutes to 90 minutes. Majority
of the studies encouraged participants to practice yoga once a
week. The longest duration included 1 hour daily yoga per
16 weeks. Only 4 studies 10,17,22,25
reported the use of power
analysis. This is a limitation of the studies utilizing yoga to
study its effect on depression.
There were 5 studies that did not have a comparison or
control group. 9,11,14,23,27
Ten studies compared yoga to no
specific treatment, including assessment(s) only 7,12,18,19,24
or standard care. 17,21,22,25,29
Two studies compared yoga to
health education. 13,20
One study each compared yoga to aerobic
exercise, 8
physical therapy, 10
instrumental music, 15
pharmaco-
logical treatment, 16
self-help, 26
and social support group. 28
Studies assessed severity of depression using the Beck’s
Depression Inventory, 10,11,27,28
Beck’s Depression Inventory-
II, 7,9
the Hamilton Rating Scale for Depression, 15,16,24,26
the
Geriatric Depression Scale, 8
the Centers for Epidemiological
Studies–Depression Scale, 12,19
Patient Health Question-
naire, 13,20,24
the Zung Depression Self Rating Scale, 14,26
Hos-
pital Anxiety Depression Scale, 17,18
the Edinburgh Postnatal
Depression Scale, 23,25
Inventory of Depression and Anxiety
Symptoms, 24
or Depression Anxiety Stress Scale. 29
The sever-
ity of anxiety or stress was assessed using the State-Trait Anxi-
ety Inventory, 7-8,10,12,13,17,20,25
Perceived Stress Scale, 11,13,20
the Zung Assessment Anxiety Self Rating Scale, 14,26
the
Hamilton Rating Scale for Anxiety, 26,27
Pregnancy Experience
Questionnaire, 17
and the Kessler Psychological Distress
Scale. 29
Health-related quality of life was assessed using the
Medical Outcome Study Health Survey, 15
World Health Orga-
nization Quality of Life–BREF, 18
and the Short Form Health
Survey. 20,29
Mindfulness was assessed using the Five Facet
Mindfulness Questionnaire 9,11,23
and the Self-Compassion
Scale. 27
Maternal-fetal attachment during pregnancy was
assessed via the Maternal Fetal Attachment Scale. 9
Pain or
illness burden was assessed using the Numerical Rating
Scale 10
; hamstring and lower back flexibility were measured
using the Sit and Reach. 10
Worry was assessed using the Penn
State Worry Questionnaire. 11
Rumination or negative think-
ing was assessed via the Rumination Response Scale. 13,20
Interpersonal factors were assessed using the Interpersonal
Sensitivity and Hostility Inventory 13,15
and the Connor-
Davidson Resilience Scale. 29
Fatigue was assessed using the
Brief Fatigue Inventory. 22
Wellness was assessed using the
Perceived Wellness Survey. 27
Table 1. Summary of Measurement Tools.
Study/Year Measurement Tools(s)
Marefat et al, 20117 Beck’s Depression Inventory-II; State-Trait Anxiety Inventory Chan et al, 20128 Geriatric Depression Scale; State-Trait Anxiety Inventory Muzik et al, 20129 Beck’s Depression Inventory-II; Edinberg Postnatal Depression Scale; The Five Facet Mindfulness Questionnaire;
The Maternal Fetal Attachment Scale Tekur et al, 201210 Beck’s Depression Inventory; State-Trait Anxiety Inventory; Numerical Rating Scale; Sit and Reach Eastman-Muller et al,
2013 11
Beck’s Depression Inventory; Perceived Stress Scale; Penn State Worry Questionnaire; The Five Facet Mindfulness Questionnaire
Field et al, 201312 The Center for Epidemiological Studies–Depression Scale; State-Trait Anxiety Inventory Kinser et al, 2013
13 Patient Health Questionnaire-9; Perceived Stress Scale-10; State-Trait Anxiety Inventory; Rumination Response
Scale; Interpersonal Sensitivity and Hostility Inventory Lakkireddy et al, 2013
14 Zung Self-Assessment Depression Score; Zung Self-Assessment Anxiety Score
Lavretsky et al, 201315 Hamilton Rating Scale for Depression; Mini-Mental State Examination; Cumulative Illness Rating Scale; Medical Outcome Study SF Health Survey
Naveen et al, 201316 Hamilton Rating Scale for Depression; Brain-derived Neurotrophic Factor; Clinical Global Impression Satyapriya et al, 2013
17 State-Trait Anxiety Inventory, Hospital Anxiety Depression Scale; Pregnancy Experience Questionnaire
Umadevi et al, 201318 Hospital Anxiety Depression Scale; World Health Organization Quality of Life–BREF Bershadsky et al, 2014
19 Center for Epidemiological Studies–Depression Scale; Cortisol via cotton swabs
Kinser et al, 201420 Patient Health Questionnaire-9; Perceived Stress Scale-10; State-Trait Anxiety Inventory; Short Form Health Survey Newham et al, 2014
21 State-Trait Anxiety Inventory; Edinberg Postnatal Depression Scale
Taso et al, 201622 Profile of Mood States; Brief Fatigue Inventory Battle et al, 2015
23 Edinberg Postnatal Depression Scale; Treatment Response to Antidepressant Questionnaire; Credibility Expectancy
Questionnaire; International Physical Activity Questionnaire; The Five-Facet Mindfulness Questionnaire Buttner et al, 2015
24 Hamilton Depression Rating Scale; Inventory of Depression & Anxiety Symptoms; Patient Health Questionnaire-9
Davis et al, 201525 Edinberg Postnatal Depression Scale; State-Trait Anxiety Inventory Doria et al, 201526 Zung Self-Assessment Anxiety Score; Zung Self-Assessment Depression Score; Hamilton Rating Scale for Depression;
Hamilton Rating Scale for Anxiety Falsafi et al, 201527 Beck Depression Inventory; Hamilton Rating Scale for Anxiety; Self-Compassion Scale; Perceived Wellness Survey Rao et al, 201528 Beck Depression Inventory Manincor et al, 201629 Depression Anxiety Stress Scale-21; Kessler Psychological Distress Scale; Short-Form Health Survey-12; Scale of
Positive and Negative Experience; Flourishing Scale; and Connor-Davidson Resilience Scale
Bridges and Sharma 1019
Study quality was assessed using the Cochrane guidelines
for systematic reviews. Results from the risk of bias assessment
showed that 4 studies had low risk of bias, 8,10,21,22
5 studies had
high risk of bias, 9,11,14,23,26,27
and 14 studies had unclear risk
of bias. 7,12,13,15-20,24,25,28,29
Risk of selection bias was generally
low as 11 studies reported adequate random sequence genera-
tion 8,10,13,15,17,18,20-22,25,29
; and 7 studies reported adequate
allocation concealment. 8,10,18,21,22,28,29
Risk for performance
bias was high as only one study reported blinding of partici-
pants and personnel; 10
and 2 studies reported blinding of out-
come assessment. 8,10
Incomplete outcome data were
adequately addressed in only 6 studies. 7,8,10,12,22,24
Risk for
selective reporting is unclear as only 3 studies had adequate
reporting. 10,21,22
Five articles were nonrandomization studies,
thus have selection bias. 11,14,25-27
Yoga as a complementary form of therapy and treatment was
found to be beneficial in the majority (n ¼ 14) of the interven- tions.
7,9-12,14,15,17-19,23,26,27,29 While in 6 interventions both
groups (yoga and control) showed improvement, 8,16,20,24,25,28
and there were no significant changes in 3 interventions. 13,21,22
One of the studies that reported no significant change con-
cluded that while yoga did not reduce depression, it prevented
an increase in depressive symptoms. 21
Significant effects of
yoga on depression were observed in the yoga group, 11
both
groups, 13,25
and yoga group compared to the control group. 17
In
one study, the yoga group reported less depressive symptoms
during the early pregnancy and postpartum periods. 19
No sig-
nificant effect was found in one study that examined yoga
intervention in reducing depressive symptoms among breast
cancer patients. 22
Discussion
The purpose of this systematic review was to examine the
effectiveness of yoga as an alternative treatment or comple-
mentary form of therapy for depression and depressive symp-
toms. In our search of the English-language peer-reviewed
literature from 4 databases, 23 interventions between 2011 and
May 2016 were evaluated. This number suggests that over the
past 5 years, there was continued interest in examining the
effectiveness of yoga practices for managing depression and
reducing depressive symptoms. This literature review provides
positive findings of yoga interventions in reducing depression
symptoms. Per this review, individuals with elevated depres-
sion levels and/or medical conditions benefited from yoga
treatment. Results also revealed that depression symptoms
improved among caregivers.
Our review found that yoga was effective in reducing
depressive symptoms in pregnant women, 9,12,17,19,21,23,25
among patients experiencing lower back pain, 10
among
patients with atrial fibrillation, 14
among persons with post-
stroke hemiparesis, 8
and addicts. 7
While most of the interven-
tions found yoga to be effective in treating depressive
symptoms, 3 studies, stroke patients, 8
pregnant patients, 21
and
breast cancer patients, 22
found no significant impact. In this
review, there were similar studies that reported a positive effect
of yoga and depression, which differ from some of the non-
significant results. There were 2 studies examining the effect of
yoga in reducing depression symptoms; while one study did not
find a significant impact of depression among breast cancer
patients, 22
the study did find a positive impact. This is also true
for other studies finding a positive impact of yoga in decreasing
depressive symptoms in pregnant women 9,12,17,19,23,25
and
postpartum depression. 18
Some factors that could affect the
results are the difference in geological locations, difference
in the styles of yoga used, sample characteristics, and duration
of yoga intervention. This warrants more research on the effect
of yoga for specific population groups such as depressed
patients with breast cancer to understand the factors that are
associated with the mixed results.
Various yoga methods were used in these studies with Hatha
yoga 8,13,19-20
being the most, followed by asana pra-
nayama, 10,18,23
and the Western adaptation of yoga, mindful-
ness meditation 9,11,17
and Viniyoga. 24,25,29
It was not evident
from the review that any one type/school of yoga was better
than the other. They all reported reductions in depressive symp-
toms among participants in the yoga groups. However, Hatha
yoga has been identified as one of the most commonly used
form of yoga in the United States. 30
Regardless of the length of the intervention, the interven-
tions proved to be efficacious. For example, the shortest yoga
Figure 1. Article selection process to locate articles for review.
1020 Journal of Evidence-Based Complementary & Alternative Medicine 22(4)
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ss io
n w
as si
gn if ic
an t
[F (1
, 7 8 ) ¼
5 .8
5 , P ¼
.0 1 8 ],
w it h
si gn
if ic
an t
d if fe
re n ce
b e tw
e e n
gr o u p s
(P <
.0 0 1 )
D e p re
ss io
n d e cr
e as
e d
in b o th
gr o u p s:
4 7 %
in yo
ga gr
o u p
(P <
.0 0 1 ,e
ff e ct
si ze
[E S ] ¼
0 .9
6 ),
1 9 %
in co
n tr
o l gr
o u p
(P <
.0 0 1 , E S
0 .5
9 )
S p in
al m
o b ili
ty im
p ro
ve d
in yo
ga gr
o u p
(5 0 %
) an
d co
n tr
o l gr
o u p
(3 4 .6
% )
N R
S an
d S A
R gr
o u p �
ti m
e in
te ra
ct io
n w
as si
gn if ic
an t
E as
tm an
-M u lle
r e t
al ,1
1 U
S A
2 0 1 3
Y o ga
-n id
ra —
W e e k ly
: 2
h o u r
cl as
se s
o f
re la
x at
io n
vi a
b o d y
se n si
n g,
b re
at h
aw ar
e n e ss
e x e rc
is e ; si
le n ce
to in
te gr
at e
e x p e ri
e n ce
; w
o rk
w it h
co n fl ic
ti n g
e m
o ti o n s
fo r
8 w
e e k s
1 8 -5
6 B as
e lin
e ; 8
w e e k s
Q u as
i- e x p e ri
m e n ta
l, 6 6
gr ad
u at
e an
d u n d e rg
ra d u at
e st
u d e n ts
e x p e ri
e n ci
n g
st re
ss , an
x ie
ty ,
an d
w o rr
y
T h e re
w as
a st
at is
ti ca
l si
gn if ic
an t
p re
- to
p o st
te st
im p ro
ve m
e n t
in st
re ss
, d e p re
ss io
n , an
d w
o rr
y
F ie
ld e t
al ,1
2 U
S A
2 0 1 3
T ai
ch i/ yo
ga —
W e e k ly
: 2 0 -m
in u te
se ss
io n s
o f
st re
tc h e s
an d
m o d e ra
te ly
ae ro
b ic
e x e rc
is e s
fo r
1 2
w e e k s
C o n tr
o l—
T ai
ch i/ yo
ga at
e n d
o f tr
e at
m e n t
p e ri
o d ; as
se ss
m e n ts
1 8 -3
7 B as
e lin
e ; 1 2
w e e k s
P re
te st
/p o st
te st
, 9 2
cl in
ic al
ly d e p re
ss e d
p re
gn an
t w
o m
e n
(w it h
o n ly
o n e
ch ild
) an
d h av
e n o
m e d ic
al p ro
b le
m s;
n o t
u si
n g
d ru
gs
T ai
ch i/ yo
ga sh
o w
e d
si gn
if ic
an t
gr o u p �
tr e at
m e n t
re d u ct
io n
in an
x ie
ty an
d d e p re
ss io
n (P ¼
.0 1 )
an d
sl e e p
d is
tu rb
an ce
s (P ¼
.0 5 )
(c o n ti n u ed
)
1021
T a b
le 2 .
(c o n ti n u e d )
S tu
d y,
C o u n tr
y Y
e ar
In te
rv e n ti o n
an d
D e sc
ri p ti o n
A ge
T im
e o f
A ss
e ss
m e n t
D e si
gn an
d S am
p le
S iz
e S al
ie n t
F in
d in
gs
K in
se r
e t
al ,1
3 U
S A
2 0 1 3
Y o ga
— W
e e k ly
: 7 5 -m
in u te
H a th
a yo
ga cl
as s;
d ai
ly h o m
e p ra
ct ic
e s
vi a
D V
D ; fo
r 8
w e e k s
A tt
e n ti o n -c
o n tr
o l gr
o u p —
H e al
th e d u ca
ti o n
se ss
io n s
o n
w e e k ly
to p ic
s; re
so u rc
e s
o n
w e e k ly
to p ic
s; fo
r 8
w e e k s
> 1 8
B as
e lin
e ; 2 , 6 , 8
w e e k s
R an
d o m
iz e d ,2
7 w
o m
e n
d ia
gn o se
d w
it h
m aj
o r
d e p re
ss iv
e d is
o rd
e r
(M D
D )
T h e re
w e re
n o
si gn
if ic
an t
gr o u p �
ti m
e d if fe
re n ce
in d e p re
ss io
n sc
o re
b e tw
e e n
th e
yo ga
an d
co n tr
o lg
ro u p s;
th e
tr e n d
in gr
o u p �
ti m
e (P ¼
.0 8 3 )
su gg
e st
s th
at th
e yo
ga gr
o u p
co m
p ar
e d
to th
e co
n tr
o l
gr o u p
h ad
re d u ce
d ru
m in
at io
n sc
o re
o ve
r ti m
e L ak
k ir
e d d y
e t
al ,1
4
U S A
2 0 1 3
P re
yo ga
— 3 -m
o n th
n o
in te
rv e n ti o n
o b se
rv at
io n
p e ri
o d
Y o ga
in te
rv e n ti o n —
T w
ic e
p e r
w e e k : 6 0 -
m in
u te
s Iy
en ga
r yo
ga , p ra
n a ya
m a s,
w ar
m -u
p e x e rc
is e s,
a sa
n a s,
an d
re la
x at
io n
e x e rc
is e s
fo r
1 2
w e e k s
1 8 -8
0 B as
e lin
e ; 1 2
w e e k s
P re
te st
/p o st
te st
, 4 9
at ri
al fi b ri
lla ti o n
p at
ie n ts
T h e re
w as
a si
gn if ic
an t
im p ro
ve m
e n t
(P <
.0 0 1 )
in th
e d e p re
ss io
n an
d an
x ie
ty sc
o re
s in
at ri
al fi b ri
lla ti o n
(A F )
p at
ie n ts
u p o n
co m
p le
ti o n
o f th
e yo
ga in
te rv
e n ti o n
p h as
e Y
o ga
si gn
if ic
an tl y
re d u ce
d th
e am
o u n t
o f
sy m
p to
m at
ic A
F e p is
o d e s,
sy m
p to
m at
ic n o n -A
F e p is
o d e s,
an d
as ym
p to
m at
ic A
F e p is
o d e s
(P <
.0 0 1 )
fr o m
th e
e n d
o f th
e co
n tr
o l p h as
e to
th e
e n d
o f th
e in
te rv
e n ti o n
L av
re ts
k y
e t
al ,1
5
U S A
2 0 1 3
K ir ta
n K ri ya
yo ga
— D
ai ly
1 2 -m
in u te
s yo
ga re
la x at
io n
b re
at h in
g an
d m
e d it at
io n
ch an
ti n g
fo r
8 w
e e k s
R e la
x at
io n
gr o u p —
D ai
ly 1 2 -m
in u te
s o f
lis te
n in
g to
in st
ru m
e n ta
l m
u si
c o n
C D
fo r
8 w
e e k s
4 5 -9
1 B as
e lin
e ; 8
w e e k s
R an
d o m
iz e d , 3 9
fa m
ily d e m
e n ti a
ca re
gi ve
rs T
h e re
w e re
si gn
if ic
an t
im p ro
ve m
e n ts
in d e p re
ss iv
e sy
m p to
m s,
m e n ta
lh e al
th ,a
n d
co gn
it io
n (P
< .0
5 )
an d
te lo
m e ra
se ac
ti vi
ty (P ¼
.0 5 )
in th
e yo
ga gr
o u p
co m
p ar
e d
to th
e co
n tr
o l
S ig
n if ic
an t
co rr
e la
ti o n s
w e re
fo u n d
b e tw
e e n
te lo
m e ra
se ac
ti vi
ty , d e cl
in e
in d e p re
ss io
n (r ¼
.3 3 ; P ¼
.0 5 )
an d
m e n ta
l h e al
th (r ¼
.4 4 ;P ¼
.0 5 ) in
al lp
ar ti ci
p an
ts N
av e e n
e t al
,1 6
Ir an
2 0 1 3
Y o ga
-o n ly
— A
tt e n d
d ai
ly gr
o u p s
fo r
1 0
d ay
s to
le ar
n yo
ga p ra
ct ic
e s;
p e rf
o rm
yo ga
in ce
n te
r 1
h /w
e e k
fo r
th e
n e x t
2 w
e e k s;
h o m
e p ra
ct ic
e s;
b o o st
e r
yo ga
se ss
io n
at e n d
o f 2
m o n th
s Y
o ga
an d
m e d ic
at io
n —
A tt
e n d
d ai
ly gr
o u p s
fo r
1 0
d ay
s to
le ar
n yo
ga p ra
ct ic
e s;
p e rf
o rm
yo ga
in ce
n te
r 1
h /w
e e k
fo r
2 w
e e k s;
h o m
e p ra
ct ic
e s;
an ti d e p re
ss an
ts an
d co
n su
lt at
io n ;
b o o st
e r
yo ga
se ss
io n
at e n d
o f 2
m o n th
s M
e d ic
at io
n al
o n e —
an ti d e p re
ss an
ts an
d co
n su
lt at
io n
1 8 -5
5 B as
e lin
e ; 1 2
w e e k s
P re
te st
/p o st
te st
, 6 2
d e p re
ss io
n d is
o rd
e r
p at
ie n ts
at te
n d in
g o u tp
at ie
n t
se rv
ic e s
D e p re
ss io
n sc
o re
s d ro
p p e d
si gn
if ic
an tl y
o ve
r ti m
e in
al lg
ro u p s
[F ¼
2 7 1 .7
;d f ¼
1 ,
5 9 ; P
< .0
0 1 ]
Y o ga
gr o u p s
h ad
gr e at
e r
im p ro
ve m
e n t
th an
th e
m e d ic
at io
n o n ly
gr o u p
[F ¼
5 .7
; d f ¼
2 , 5 9 ; P
< .0
0 5 ]
w h e n
e x am
in in
g gr
o u p
e ff e ct
In th
e yo
ga -o
n ly
gr o u p ,t
h e re
w as
a p o si
ti ve
co rr
e la
ti o n
b e tw
e e n
th e
d e cl
in e
in d e p re
ss io
n an
d a
ri se
in b ra
in d e ri
ve d
n e u ro
tr o p ic
fa ct
o r
le ve
ls (r ¼
.7 0 2 ,
P ¼
.0 0 1 )
(c o n ti n u ed
)
1022
T a b
le 2 .
(c o n ti n u e d )
S tu
d y,
C o u n tr
y Y
e ar
In te
rv e n ti o n
an d
D e sc
ri p ti o n
A ge
T im
e o f
A ss
e ss
m e n t
D e si
gn an
d S am
p le
S iz
e S al
ie n t
F in
d in
gs
S at
ya p ri
ya e t
al ,1
7
In d ia
2 0 1 3
Y o ga
— D
ai ly
1 h o u r:
IA Y T
a sa
n a
p o st
u re
s; p ra
n a ya
m a , m
e d it at
io n
fo r
1 6
w e e k s
C o n tr
o l—
S ta
n d ar
d ca
re ; as
se ss
m e n ts
2 0 -3
5 B as
e lin
e ; 2 0 th
ge st
at io
n ; 3 6 th
ge st
at io
n
R an
d o m
iz e d , 9 6
w o m
e n
b e tw
e e n
1 8 th
an d
1 9 th
ge st
at io
n (w
it h
o n ly
o n e
ch ild
)
D e p re
ss io
n sc
o re
s d e cr
e as
e d
in yo
ga (3
0 .6
7 %
, P
< .0
0 1 )
w it h
si gn
if ic
an t
d if fe
re n ce
in gr
o u p s
b u t
in cr
e as
e d
3 .5
7 %
in co
n tr
o l
A n x ie
ty sc
o re
s d e cr
e as
e d
in yo
ga (2
9 .1
2 %
, P
< .0
0 1 )
w it h
si gn
if ic
an t
d if fe
re n ce
in gr
o u p s
T h e re
w as
si gn
if ic
an t
ch an
ge in
P E Q
sc o re
s am
o n g
yo ga
gr o u p
(P <
.0 0 0 1 )
U m
ad e vi
e t
al ,1
8
In d ia
2 0 1 3
Y o ga
gr o u p —
1 0
d ay
s o f ta
u gh
t a sa
n a s
an d
p ra
n a ya
m a ; 2 0
d ay
s o f yo
ga p ra
ct ic
e s
o n
th e ir
o w
n C
o n tr
o l gr
o u p —
A ss
e ss
m e n ts
o n ly
1 8 -6
0 B as
e lin
e ; 4
w e e k s
R an
d o m
iz e d , 6 0
ca re
gi ve
rs o f
p at
ie n ts
in n e u ro
lo gy
w ar
d s
w h o
co u ld
p e rf
o rm
yo ga
A si
gn if ic
an t
(P <
.0 0 1 )
re d u ct
io n
in an
x ie
ty an
d d e p re
ss io
n sc
o re
s an
d im
p ro
ve d
q u al
it y-
o f-
lif e
to o k
p la
ce am
o n g
yo ga
gr o u p
co m
p ar
e d
to th
e co
n tr
o l gr
o u p
B e rs
h ad
sk y
e t
al ,1
9
U S A
2 0 1 4
H a th
a yo
ga —
9 0 -m
in u te
yo ga
tw ic
e : e ar
ly an
d m
id p re
gn an
cy : b o d y
p o st
u re
s, st
re tc
h in
g, sa
va sa
n a , p ra
n a ya
m a , sa
liv a
sa m
p le
at b as
e lin
e an
d co
m p le
ti o n
o f yo
ga C
o n tr
o l—
A ss
e ss
m e n t
o n ly
> 1 8
B as
e lin
e ; 2 �
e ar
ly p re
gn an
cy ; 2 �
m id
-p re
gn an
cy ; 2
m o n th
s af
te r
d e liv
e ry
R an
d o m
iz e d , 5 1
p e ri
n at
al d e p re
ss e d
w o m
e n
b e tw
e e n
1 2 th
an d
1 9 th
ge st
at io
n ; d id
n o t
p ra
ct ic
e yo
ga o r
re la
x at
io n
te ch
n iq
u e s
W o m
e n
in th
e yo
ga gr
o u p
re p o rt
e d
le ss
d e p re
ss iv
e sy
m p to
m s
th an
w o m
e n
in th
e co
n tr
o l gr
o u p
in th
e p o st
p ar
tu m
p e ri
o d
af te
r co
n tr
o lli
n g
fo r
an te
p ar
tu m
d e p re
ss iv
e sy
m p to
m s
in e ar
ly an
d m
id -
p re
gn an
cy W
o m
e n
w h o
p ra
ct ic
e d
yo ga
at le
as t tw
ic e
a w
e e k
p ri
o r
to fi rs
t as
se ss
m e n t
re p o rt
e d
fe w
e r
d e p re
ss io
n sy
m p to
m s
(M ¼
2 .1
3 ,
S D ¼
1 .5
5 )
th an
w o m
e n
p ra
ct ic
in g
yo ga
le ss
(M ¼
4 .7
2 , S D ¼
2 .7
2 ; t(
2 4 ) ¼
2 .5
1 ,
P <
.0 5 )
C o rt
is o l le
ve ls
w e re
lo w
e r
in yo
ga co
m p ar
e d
to co
n tr
o l gr
o u p
in e ar
ly p re
gn an
cy (b ¼ �
.5 0 ,S
E ¼
.2 3 ,P ¼
.0 2 9 )
b u t
d id
n o t
ch an
ge o ve
r ti m
e , n o
tr aj
e ct
o ri
e s
w e re
o b se
rv e d
b e tw
e e n
gr o u p s
(b ¼ �
.0 1 , S E ¼
.2 0 , n s)
K in
se r
e t
al ,2
0 U
S A
2 0 1 4
Y o ga
gr o u p —
W e e k ly
: 7 5 -m
in u te
H a th
a yo
ga ;
b re
at h in
g an
d re
la x at
io n
p ra
ct ic
e s
fo r
8 w
e e k s
C o n tr
o l gr
o u p —
W e e k ly
: 7 5 -m
in u te
h e al
th e d u ca
ti o n
se ss
io n
fo r
8 w
e e k s
> 1 8
B as
e lin
e ; 2 , 4 , 6 , 8
w e e k s;
5 2
w e e k
R an
d o m
iz e d , 7 7
w o m
e n
w it h
M D
D o r
d ys
th ym
ia d ia
gn o si
s; ca
n p ar
ti ci
p at
e in
yo ga
P ar
ti ci
p an
ts in
b o th
gr o u p
sh o w
e d
a si
gn if ic
an t
re d u ct
io n
in d e p re
ss io
n o ve
r ti m
e T
h e
yo ga
gr o u p
m ai
n ta
in e d
a m
ild le
ve l o f
d e p re
ss io
n 1
ye ar
af te
r th
e in
te rv
e n ti o n
B o th
gr o u p s
re p o rt
e d
a si
gn if ic
an t d e cr
e as
e in
p e rc
e iv
e d
st re
ss , st
at e
an x ie
ty , an
d h e al
th -r
e la
te d
q u al
it y
o f lif
e
(c o n ti n u ed
)
1023
T a b
le 2 .
(c o n ti n u e d )
S tu
d y,
C o u n tr
y Y
e ar
In te
rv e n ti o n
an d
D e sc
ri p ti o n
A ge
T im
e o f
A ss
e ss
m e n t
D e si
gn an
d S am
p le
S iz
e S al
ie n t
F in
d in
gs
N e w
h am
e t
al ,2
1
U K
2 0 1 4
A n te
n at
al yo
ga —
E x e rc
is e s,
p o st
u re
s, an
d re
la x at
io n /b
re at
h in
g m
e th
o d s
fo r
8 w
e e k s
C o n tr
o l—
T re
at m
e n t
as u su
al , as
se ss
m e n t
> 1 8
B as
e lin
e ; 8
w e e k s
R an
d o m
iz e d , 5 9
lo w
-r is
k w
o m
e n
in th
e se
co n d
an d
e ar
ly th
ir d
tr im
e st
e r
(f ir
st p re
gn an
cy an
d h ig
h an
x ie
ty )
Y o ga
se ss
io n s
w e re
e ff e ct
iv e
in re
d u ci
n g
an x ie
ty at
th e
b e gi
n n in
g (3
7 [I
Q R ¼
3 0 -
4 4 ])
an d
th e
e n d
o f th
e 8 -w
e e k
p ro
gr am
(3 2
[I Q
R ¼
2 5 -3
9 ])
D e p re
ss io
n sc
o re
s d id
n o t
ch an
ge o ve
r ti m
e ; h o w
e ve
r, d e p re
ss io
n sc
o re
s w
e re
si gn
if ic
an tl y
gr e at
e r
am o n g
w o m
e n
in th
e co
n tr
o l gr
o u p
co m
p ar
e d
to th
e w
o m
e n
in th
e yo
ga gr
o u p
C o rt
is o l le
ve ls
in cr
e as
e d
as ge
st at
io n
ad va
n ce
d T
as o
e t
al ,2
2
T ai
w an
2 0 1 4
A n u sa
ra yo
ga gr
o u p —
6 0 -m
in u te
yo ga
,2 ti m
e s
a w
e e k : st
re tc
h in
g an
d re
la x at
io n
e x e rc
is e s;
fo r
8 w
e e k s
C o n tr
o l gr
o u p —
T re
at m
e n t
as u su
al
2 0 -7
0 B as
e lin
e ; 4 , 8
w e e k s;
4 w
e e k s
af te
r
R an
d o m
iz e d ,6
0 st
at e
I, II ,I
II b re
as t
ca n ce
r, n e ve
r p e rf
o rm
e d
yo ga
, n o
m e n ta
l h e al
th h is
to ry
T h e re
w e re
si gn
if ic
an t
ti m
e an
d gr
o u p s
fo r
fa ti gu
e le
ve l (F ¼
7 5 .4
9 , P
< .0
0 1 )
an d
in fl u e n ce
o f fa
ti gu
e o n
d ai
ly liv
e s
(F ¼
5 1 .7
1 , P
< .0
0 1 )
an d
n o
si gn
if ic
an t
in te
ra ct
io n
e ff e ct
s fo
r d e p re
ss io
n an
d an
x ie
ty (P
> .0
5 )
B at
tl e
e t
al ,2
3 U
S A
2 0 1 5
P re
n at
al yo
ga —
T w
ic e
p e r
w e e k
7 5
m in
u te
cl as
se s;
p ra
n a ya
m a ;h
o m
e yo
ga fo
r 1 0
w e e k s
> 1 8
B as
e lin
e ; 1 0
w e e k s
Q u as
i- e x p e ri
m e n ta
l, 3 4
d e p re
ss e d
w o m
e n
b e tw
e e n
1 2
an d
2 6
w e e k s’
ge st
at io
n
W o m
e n
e x p e ri
e n ce
d a
si gn
if ic
an t
re d u ct
io n
in d e p re
ss io
n sy
m p to
m s
o ve
r ti m
e B u tt
n e r
e t
al ,2
4
U S A
2 0 1 5
Y o ga
gr o u p —
1 6
o n e -h
o u r
cl as
se s:
su n
sa lu
ta ti o n s,
b al
an ci
n g,
tw is
ti n g,
an d
re la
x at
io n
p o se
s; 3 0 -m
in u te
h o m
e yo
ga vi
a D
V D
fo r
8 w
e e k s
W L C
gr o u p —
A ss
e ss
m e n ts
o n ly
1 8 -4
5 B as
e lin
e ; 2 , 4 , 6 , 8
w e e k s
R an
d o m
iz e d , 5 7
p o st
p ar
tu m
w o m
e n
D e p re
ss iv
e sy
m p to
m s
d e cr
e as
e d
o ve
r ti m
e fo
r b o th
gr o u p s
(t ¼ �
1 0 .1
7 ;d
f ¼
5 5 ;P
< .0
0 0 1 )
Y o ga
gr o u p
p ar
ti ci
p an
ts e x p e ri
e n ce
d a
st e e p e r
lin e ar
d e cl
in e
in d e p re
ss iv
e sy
m p to
m s
(t ¼ �
2 .9
4 ;d
f ¼
5 2 ;P ¼
.0 0 5 )
an d
an x ie
ty sy
m p to
m s
(t ¼ �
3 .2
6 ; d f ¼
5 2 ; P ¼
.0 0 2 )
an d
st e e p e r
lin e ar
in cr
e as
e in
w e ll-
b e in
g sc
al e
sc o re
s (t ¼
2 .9
4 ; d f ¼
5 2 ; P ¼
.0 0 5 )
co m
p ar
e d
to th
e co
n tr
o l
gr o u p
D av
is e t
al ,2
5 U
S A
2 0 1 5
Y o ga
— W
e e k ly
: 7 5 -m
in u te
cl as
se s—
sy n ch
ro n iz
in g
b re
at h , m
o ve
m e n t
an d
st an
d in
g p o st
u re
fo r
8 w
e e k s
C o n tr
o l—
T re
at m
e n t
as u su
al ; as
se ss
m e n ts
1 8 -4
5 B as
e lin
e ; 4 , 8
w e e k s
R an
d o m
iz e d , 4 6
w o m
e n
u p
to 2 8
w e e k
ge st
at io
n T
h e re
w as
a si
gn if ic
an t
im p ro
ve m
e n t
in d e p re
ss io
n an
d an
x ie
ty sc
o re
s fo
r b o th
gr o u p s
o ve
r ti m
e
D o ri
a e t
al ,2
6 It
al y
2 0 1 5
S K
Y gr
o u p
1 —
P re
: m
in im
u m
o f 6
m o n th
s p h ar
m ac
o lo
gi ca
l tr
e at
m e n t w
it h
m e d ic
at io
n ;
b re
at h in
g e x e rc
is e s
S K
Y gr
o u p
2 —
P re
: m
in im
u m
o f 6
m o n th
s se
lf -
h e lp
gr o u p s;
b re
at h in
g e x e rc
is e s
2 5 -6
4 B as
e lin
e ; 3 , 6
m o n th
s; 1 5
d ay
s af
te r
P re
te st
/p o st
te st
, 6 9
w o m
e n
w it h
ge n e ra
liz e d
an x ie
ty A
n x ie
ty sc
o re
s si
gn if ic
an tl y
d e cr
e as
e d
(P <
.0 0 1 )
am o n g
S K
Y gr
o u p
b e tw
e e n
b as
e lin
e an
d 1 5
d ay
s af
te r
tr e at
m e n t
D e p re
ss io
n sc
o re
s si
gn if ic
an tl y
d e cr
e as
e d
(P <
.0 0 1 )
o ve
r ti m
e fo
r S K
Y gr
o u p
(c o n ti n u ed
)
1024
T a b
le 2 .
(c o n ti n u e d )
S tu
d y,
C o u n tr
y Y
e ar
In te
rv e n ti o n
an d
D e sc
ri p ti o n
A ge
T im
e o f
A ss
e ss
m e n t
D e si
gn an
d S am
p le
S iz
e S al
ie n t
F in
d in
gs
F al
sa fi
e t
al ,2
7 U
S A
2 0 1 5
In te
rv e n ti o n —
1 .5
h o u rs
p e r
w e e k
o f
m in
d fu
ln e ss
, se
lf -c
o m
p as
si o n
an d
yo ga
tr ai
n in
g; m
at e ri
al s
fo r
h o m
e p ra
ct ic
e fo
r 8
w e e k s
1 8 -6
5 B as
e lin
e ; 4 , 6 , 8
w e e k s;
1 m
o n th
af te
r
Q u as
i- e x p e ri
m e n ta
l, 1 8
u n in
su re
d p at
ie n ts
w it h
in co
m e
b e lo
w 1 5 0 %
o f th
e fe
d e ra
l p o ve
rt y
le ve
l; an
x ie
ty
T h e re
w as
st at
is ti ca
l si
gn if ic
an t
d e cr
e as
e in
d e p re
ss iv
e sy
m p to
m s
sc o re
s fr
o m
p re
- to
p o st
te st
an d
fr o m
p re
te st
to fo
llo w
- u p
(P <
.0 5 )
T h e re
w e re
al so
st at
is ti ca
l im
p ro
ve m
e n ts
in an
x ie
ty (P
< .0
5 ) fr
o m
p re
- to
p o st
te st
an d
fo llo
w -u
p (P
< .1
0 );
an d
se lf -
co m
p as
si o n
an d
ge n e ra
l w
e ll-
b e in
g fr
o m
p re
-t o
fo llo
w -u
p (P
< .0
5 )
R ao
e t
al ,2
8 In
d ia
2 0 1 5
Y o ga
gr o u p —
A se
t o f a sa
n a s,
b re
at h in
g e x e rc
is e s,
p ra
n a ya
m a , m
e d it at
io n
an d
yo gi
c re
la x at
io n
te ch
n iq
u e s
w it h
im ag
e ry
fo r
2 4
w e e k s
C o n tr
o l gr
o u p —
S u p p o rt
iv e
th e ra
p y:
k n o w
le d ge
o f d is
e as
e an
d tr
e at
m e n t
o p ti o n s,
e x p re
ss th
e ir
p ro
b le
m s,
st re
n gt
h e n
re la
ti o n sh
ip s,
an d
fi n d
m e an
in g
in th
e ir
liv e s
fo r
2 4
w e e k s
3 0 -7
0 B as
e lin
e ; b e fo
re ,
d u ri
n g,
an d
af te
r su
rg e ry
R an
d o m
iz e d , 6 9
st ag
e II
an d
II I
b re
as t
ca n ce
r p at
ie n ts
u n d e rg
o in
g su
rg e ry
fo llo
w e d
b y
ad ju
va n t
ra d io
th e ra
p y
an d /o
r ch
e m
o th
e ra
p y
B o th
gr o u p s
re p o rt
e d
a re
d u ct
io n
in th
e ir
d e p re
ss io
n o ve
r ti m
e T
h e
yo ga
gr o u p
sh o w
e d
a d e cr
e as
e in
d e p re
ss io
n sc
o re
b e fo
re (F
(5 7 ) ¼
6 .0
2 , P
¼ .0
2 ),
an d
af te
r (F
(5 7 ) ¼
1 0 .9
0 , P ¼
.0 0 2 )
ch e m
o th
e ra
p y
co m
p ar
e d
to th
e co
n tr
o l gr
o u p
T h e re
w as
a p o si
ti ve
si gn
if ic
an t
co rr
e la
ti o n
b e tw
e e n
d e p re
ss io
n sc
o re
s o f sy
m p to
m se
ve ri
ty an
d an
d d is
tr e ss
d u ri
n g
ad ju
va n t
ra d io
th e ra
p y
an d
ch e m
o th
e ra
p y
M an
in co
r e t
al ,2
9
A u st
ra lia
2 0 1 6
Y o ga
gr o u p —
1 d ay
a w
e e k
V in
iy o ga
; tr
e at
m e n t
as u su
al fo
r 6
w e e k s
C o n tr
o l gr
o u p —
T re
at m
e n t
as u su
al ;
as se
ss m
e n ts
> 1 8
B as
e lin
e ; 6
w e e k s
R an
d o m
iz e d , 1 0 1
d e p re
ss e d
an d
an x ie
ty p at
ie n ts
S ta
ti st
ic al
ly si
gn if ic
an t
d if fe
re n ce
s o n
re d u ce
d d e p re
ss io
n sc
o re
s w
e re
fo u n d
in yo
ga gr
o u p
co m
p ar
e d
to th
e co
n tr
o l
gr o u p
(� 4 .3
0 ;9
5 %
C I: �
7 .7
0 ,�
0 .0
1 ;P ¼
.0 1 ; E S �
.4 4 );
d if fe
re n ce
in re
d u ce
d an
x ie
ty sc
o re
s w
e re
n o t
st at
is ti ca
lly si
gn if ic
an t
(� 1 .9
1 ; 9 5 %
C I: �
4 .5
8 , 0 .7
6 ;
P ¼
.1 6 )
S ta
ti st
ic al
ly si
gn if ic
an t
d if fe
re n ce
s fa
vo ri
n g
yo ga
w as
fo u n d
o n
to ta
l d e p re
ss io
n an
d an
x ie
ty sc
o re
s (P ¼
.0 3 )
A b b re
vi at
io n s:
IA Y
T , in
te gr
at e d
ap p ro
ac h
o f yo
ga th
e ra
p y;
S K
Y , S u rd
a sh
a n
K ri ya
yo ga
.
1025
intervention with depressed patients with chronic back pain 10
showed positive results. These findings suggest that brief yoga
treatment or therapy can be effective in reducing depressive
symptoms. The longest intervention 19
followed women
through their pregnancy to 2 months postpregnancy. The preg-
nant women showed a reduction in depressive symptoms.
These findings suggest that yoga interventions can have a
long-term positive effect on depressive symptoms. Seven stud-
ies implemented some form of follow-up with participants after
the intervention; 11,13,17-20,22,27,28
only in 6 studies did effects
persist. 11,13,17,19,22,25
There were many commonalities in the articles reviewed. Per
this current review of literature, common interest of yoga and
depression took place with pregnant and postpartum women
(n ¼ 7), patients diagnosed with a depressive disorder (n ¼ 4), caregivers (n ¼ 2), and breast cancer patient (n ¼ 2). They reported positive impacts of yoga in treating depression in
patients. This information gives value to the positive effect yoga
has in reducing depression among these groups. Most of the
studies examined the effect of yoga on depressed patients with
medical (n ¼ 13) and mental health conditions (n ¼ 6). Two studies examined the impact of yoga on reducing depression
among caregivers. 15,18
As both reported positive effects, more
research is needed for caregivers of medical and mental health
patients. Another commonality of the interventions involved
yoga practices among the adult population. Only one study 11
examined the effectiveness of yoga for treating depression,
stress, and worry among college students. As yoga was found
to reduce depressive symptoms in college students, more studies
are needed to add to the body of knowledge with this population.
These findings provide support for mind-body interventions
such as yoga for improving depression symptoms. While mind-
body interventions may not be more effective than existing
evidence-based treatments for depression, 31
there is one great
benefit. Yoga can serve as alternative to many individuals who
may not participate in psychotherapy or antidepressants due to
factors such as side effects, unmet needs, lack of access/
resource, and personal choice.
The results of this review are in line with those of prior
systematic reviews on yoga for depression. Two systematic
reviews found evidence of the effectiveness of yoga for reduc-
ing depression; 32,33
another more recent review article reported
that yoga was better than usual care, relaxation techniques, or
aerobic exercises in reducing depressive symptoms. 34
Limitations of the Interventions
There were some limitations of the interventions. Majority of
the studies utilized a small sample, which limits the power of
statistical analysis. Many of the studies were randomized con-
trolled trials; however, there were also other designs used.
Next, majority of the studies examined the short-term effects
of yoga to treat depression. Studies examining the long-term
effectiveness of yoga for depression are limited and more stud-
ies in this area are warranted. While the literature reports find-
ings on various population and study area, it limits the variety
Table 3. Risk of Bias in Included Studies.
Study, Year
Random Sequence Generation
Allocation Concealment
Blinding of Participants and Personnel
Blinding of Outcome Assessment
Incomplete Outcome Data
Selective Reporting Other Bias
Marefa et al,7 2011 Unclear No No No Yes Unclear Unclear Chan et al,8 2012 Yes Yes Unclear Yes Yes Unclear None Muzik et al,9 2012 No No No No Unclear Unclear Unclear Tekur et al,10 2012 Yes Yes Yes Yes Yes Yes None Eastman-Muller et al,
11 2013 No No No No Unclear Unclear Yes
Field et al,12 2013 Unclear Unclear Unclear Unclear Yes Unclear Unclear Kinser et al,
13 2013 Yes Unclear Unclear Unclear No Unclear Unclear
Lakkireddy et al,14 2013 No No No No Unclear Unclear Yes Lavretsky et al,
15 2013 Yes Unclear Unclear Unclear Unclear Unclear Unclear
Naveen et al,162013 No No No No No Unclear Unclear Satyapriya et al,
17 2013 Yes Unclear No No Unclear Unclear Unclear
Umadevi et al,18 2013 Yes Yes Unclear Unclear Unclear Unclear Unclear Bershadsky et al,
19 2014 Unclear Unclear Unclear Unclear No Unclear Unclear
Kinser et al,20 2014 Yes Unclear Unclear Unclear No Unclear Unclear Newham et al,
21 2014 Yes Yes Unclear Unclear Unclear Yes Unclear
Taso et al,22 2014 Yes Yes Unclear Unclear Yes Yes None Battle et al,
23 2015 No No No No Unclear Unclear Yes
Buttner et al,24 2015 Unclear Unclear Unclear Unclear Yes Unclear Unclear Davis et al,
25 2015 Yes Unclear Unclear Unclear Unclear Unclear Unclear
Doria et al,26 2015 No No Unclear Unclear Unclear Unclear Yes Falsafi et al,
27 2015 No No Unclear Unclear Unclear Unclear Yes
Rao et al,28 2015 Unclear Yes Unclear Unclear Unclear Unclear Unclear Manincor et al,29 2016 Yes Yes Unclear Unclear Unclear Unclear Unclear
1026 Journal of Evidence-Based Complementary & Alternative Medicine 22(4)
of literature of the effect of yoga on depression regarding other
populations and study areas. These findings support Mehta and
Sharma’s 6
suggestion for more studies that examine the effect
of yoga on depression within youth and among various ethni-
city groups, cultures, sex, and occupation. Finally, none of the
interventions utilized any behavioral theory to help participants
adhere to the practice of yoga. The use of cognitive and beha-
vioral theories and strategies are suggested because they are
used as a form of treatment for reducing depression in patients
with depressive disorder.
Limitations of This Review
There were some limitations of this review. This search only
consisted of restricted databases and there are other databases
that were not included in this research. Grey literature was not
searched in this study. Only articles in the English language
were included; articles in other languages were not included.
There could have been publication bias as many of the studies
used in this review reported positive findings and many arti-
cles with negative results may have been rejected. Quality of
studies was not assessed. Finally, studies that measured
depression or depressive symptoms as an outcome measure
were used, omitting articles that measured depression but not
as an outcome measure.
Implications for Practice
While literature on yoga intervention for depression continues to
lengthen, there continues to be a growing need for more studies
of yoga practices for treating depression and depressive symp-
toms. Based on the review, the following recommendations for
future studies are made. More studies are needed on yoga for
reducing depression and depressive symptoms in various comor-
bid mental health and physical health conditions and for care-
givers. Such research should be conducted on studies of yoga for
depression among groups such as race and ethnicity, cultures,
youth and young adults, and socioeconomic status in various
geographical location and conditions. For example, more studies
are needed on yoga for reducing depression symptoms among
the various depressive disorders and other mental health illnesses
(eg, posttraumatic stress disorder) and medical conditions (eg,
breast cancer patients) as this review reports limited research and
mixed results on these areas This will result in more knowledge
in understanding the direct impact of yoga for depressive symp-
toms among various groups of individuals.
While there are many aspects of yoga, there is also a need to
examine more of the styles and specific aspects of yoga on
depression. These will merit the full or exact understanding
of the impact that yoga has on depression. Finally, yoga inter-
ventions should utilize behavioral theories/techniques such as
social cognitive theory, 35
multi-theory model of health beha-
vior change, 36,37
and others in designing and evaluating the
interventions. This is imperative as psychotherapy techniques
are used in managing depressive symptoms and stress
management.
Conclusions
Yoga is a fairly new treatment or practice utilized for more than
mind-body fitness in the West. In fact, yoga is being used more
and more as an alternative form of treatment for improving
many conditions. One way that yoga is used is in individuals
with depressive symptoms. Recently, researchers have exam-
ined the benefits and effectiveness of depression for managing
depressive symptoms. This review reveals that yoga provides
limited evidence that a restricted number of studies (those pub-
lished between 2011 and 2015) may influence depression out-
comes in various populations. Many more interventions on the
subject area are needed to continue to learn and understand
fully the impact of yoga and depression.
Acknowledgements
We are thankful to Center for University Scholars, Jackson State
University, for awarding a graduate assistantship in order to complete
this project.
Author Contributions
MS conceptualized the study, both MS and LB retrieved the articles,
LB prepared the first draft, and MS worked on the final draft and
submission.
Declaration of Conflicting Interests
The authors declared no potential conflicts of interest with respect to
the research, authorship, and/or publication of this article.
Funding
The authors disclosed receipt of the following financial support for the
research, authorship, and/or publication of this article: Only graduate
assistantship support was provided by the Center for University Scho-
lars, Jackson State University.
Ethical Approval
As human subjects were not involved in this study, ethical approval
was not required.
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1028 Journal of Evidence-Based Complementary & Alternative Medicine 22(4)
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