journal entry psych

profilenotmelissa
SUBSTANCEABUSEDISORDERS.ppt

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SUBSTANCE ABUSE DISORDERS

LEARNING OBJECTIVES

  • Explain the disease concept of alcoholism and the following theories of addiction: biologic, genetic, behavioral and learning, sociocultural, psychodynamic, and the disease concept of alcoholism
  • Differentiate the following terms: substance use, addiction, psychological dependence, tolerance, and physiologic dependence
  • Discuss the dynamics of enabling and codependency
  • Articulate the difference between alcohol dependence and alcohol abuse

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LEARNING OBJECTIVES (CONT’D)

  • Recognize the more common physiologic effects of alcoholism
  • Identify the common medical problems associated with illicit abuse of substances (drugs)
  • Describe the rationale for the use of substance abuse screening tools during the initial assessment of a client with a substance-related disorder
  • Evaluate the treatment measures, including nursing interventions, for a client with a substance-related disorder

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LEARNING OBJECTIVES (CONT’D)

  • Formulate a list of nursing interventions for a client with clinical symptoms of acute substance intoxication
  • Develop a list of services available to clients who abuse substances

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Perspectives on Substance-Related Disorders:
An Overview

  • Five Main Categories of Substances

Depressants – Result in behavioral sedation (i.e., alcohol, barbiturates, benzodiazepines, GHB)

Hallucinogens – Alter sensory perception (i.e., LSD, PCP, Mescaline (Peyote)

Opiates – Primarily produce analgesia and depressant (i.e., heroin, morphine derivates, narcotics)

Stimulants – Increase alertness and elevate mood (i.e., amphetamines, caffeine, cocaine, ecstasy, and nicotine)

Other drugs of abuse – Include inhalants, anabolic steroids, medications

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Polysubstance abusing individual

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ALCOHOL (cont.)

  • Alcohol has greater costs to society than any other drug
  • Has the most serious effects on fetal development during the brain growth spurt period, which occurs during the last trimester of pregnancy and for several years after birth

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DSM-IV Criteria for Diagnosing Substance Abuse

One or more of the following occurs during a 12-month period:

  • Failure to fulfill important obligations at work, home, school as a result of use
  • Repeated use of the substance in physically hazardous situations

(i.e., driving a car)

  • Continued use of the substance despite social, interpersonal or legal problems as a result of use

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Abuse vs dependency

Abuse: utilizing the substance that interferes with functioning

Dependence: is a more extreme form of abuse with an increasing number of negative consequences

Dopamine is implicated for these individuals

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DSM-IV Criteria for Diagnosing Substance Dependence

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DSM-IV Criteria for Diagnosing Substance Dependence (cont.)

b) Withdrawal, physiological, behavioural, cognitive, and affective symptoms that occur after reduction or discontinuance of a drug that has been used heavily over a long period of time

Withdrawal is also a result of the altered DA system. Withdrawal and abstinence deprive the brain of the only source of DA that produces a sense of pleasure. Without the drug, life seems not worth living.

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DSM-IV Criteria for Diagnosing Substance Dependence (cont.)

  • Substance often taken in larger amounts

or over a longer period

  • Persistent desire or unsuccessful efforts

to cut down or control use

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DSM-IV Criteria for Diagnosing Substance Dependence (cont.)

  • A great deal of time is spent

Obtaining the substance

Using the substance

Recovering from the effects

  • Social, occupational, recreational activities given up or decreased

Type of drinkers:

Binge Drinkers

  • Definition:
  • Consumes large amounts of alcohol in a short period, usually on weekends or during specific periods.
  • Some may binge only on weekends, while others may drink during the week and abstain on weekends.
  • Psychological Aspect:
  • Uses Freud’s Ego Defense Mechanisms to justify their drinking behavior.
  • Rationalization: They minimize or justify their drinking (e.g., “I only drink on weekends, so it’s fine.”).

Alcohol Withdrawal:

  • Onset:
  • Symptoms typically begin 6 to 8 hours after the last drink.
  • Peak severity occurs 24 to 72 hours after cessation but can last for days to weeks, depending on the severity.

Withdrawal Symptoms:

  • Ataxia:
  • Loss of coordination, clumsy movements, and difficulty walking.
  • Vital Sign Fluctuations:
  • Blood pressure, heart rate, and respiratory rate may fluctuate due to the body adjusting to the absence of alcohol.
  • Hypertension:
  • Elevated blood pressure due to increased sympathetic nervous system activity.
  • Vomiting:
  • Nausea and vomiting as the body attempts to rid itself of toxins.
  • Headache:
  • Resulting from dehydration and changes in blood flow to the brain.

More Serious Symptoms of Alcohol Withdrawal:

  • Delirium Tremens (DTs):
  • A severe and life-threatening form of alcohol withdrawal.
  • Can cause seizures, hallucinations, confusion, heart attack, agitation
  • Onset: Usually occurs 48 to 72 hours after the last drink but can take up to 2 weeks in some cases.
  • Confabulation:
  • Filling in gaps in memory with false information, often seen in people with chronic alcohol abuse.
  • Happens due to damage in memory areas of the brain.
  • Wernicke’s Encephalopathy and Korsakoff Syndrome:
  • Both are conditions caused by thiamine (vitamin B1) deficiency, common in chronic alcoholics.
  • Wernicke’s Encephalopathy: Acute and reversible condition causing confusion, lack of coordination, and eye movement abnormalities.
  • Korsakoff Syndrome: Chronic and often irreversible condition marked by severe memory loss and confabulation.

Brain Effects:

  • Disturbance of Glutamate:
  • Alcohol suppresses glutamate, a neurotransmitter that stimulates brain activity.
  • During withdrawal, glutamate levels spike, leading to over-excitation of the brain, which causes seizures, agitation, and hallucinations seen in DTs.

Detox protocol: Librium (benzodiazepines) – low potency longer acting because we want to avoid 1 addiction substituting another addiction, Thiamine, Folic acid, Vitamin B12, B1

Detox: 3-4 days (typical)

Day 4: Librium q 4hr, Day 3 q 3 hrs, Day 2, q 2 hours – the drug is tapered throughout the 4 day period

Slow with medication management: because pt can go into resp depression

What is their history?

Detox Protocol for Alcohol Withdrawal:

1. Medications Used:

  • Librium (Chlordiazepoxide)
  • Class: Benzodiazepine
  • Why Librium?
  • Low potency and long-acting → Preferred for alcohol withdrawal to prevent severe symptoms (seizures, DTs).
  • Goal: Avoid substituting one addiction (alcohol) with another (short-acting benzodiazepines like Xanax or Ativan).
  • Tapering Protocol:
  • Day 1: Administered every 4 hours
  • Day 2: Administered every 3 hours
  • Day 3: Administered every 2 hours
  • Taper Duration: Usually over 3-4 days to gradually reduce the dosage and prevent withdrawal complications.


    Antipsychotics may be given as well because the patient may be having illusions, pt must be observed

2. Essential Vitamins and Supplements:

  • Thiamine (Vitamin B1):
  • Prevents Wernicke’s Encephalopathy and Korsakoff Syndrome.
  • Given to replace deficiencies caused by chronic alcohol use.
  • Folic Acid (Folate):
  • Helps with red blood cell production and prevents anemia caused by poor nutrition in alcoholics.
  • Vitamin B12:
  • Supports nerve function and helps prevent further neurological damage.

3. Duration of Detox:

  • Typical Length:
  • 3 to 4 days depending on the severity of withdrawal and patient response.

4. Tapering Librium Schedule (Example):

  • Day 1: Librium every 6-8 hours 50 mg
  • Day 2: Librium every 6-8 hours 25 mg
  • Day 3: Librium every 6-8 hours 15 mg
  • Day 4: Gradual tapering and discontinuation

    Librium may not be necessary if mild withdrawals or when the pt is about to be discharged

5. Why Slow Medication Tapering is Important:

  • Risk of Respiratory Depression:
  • Benzodiazepines (like Librium) depress the central nervous system.
  • Rapid administration or high doses may cause respiratory depression, sedation, and coma.
  • Goal: Use the minimum effective dose and taper gradually to avoid complications.

✅ Key Points:

  • Librium is used for safe withdrawal and to prevent seizures/DTs.
  • Vitamin replacement prevents long-term neurological damage.
  • Slow tapering minimizes the risk of respiratory depression.

    Flushed red, puffy appearance, ascites (perfusion of abdomen), ulcer bleeding, Liver becomes affected.
    History of patient: what is the cause of the alcoholism? Could be genetics

As a younger child the individual may have had to take over the parent role to their younger siblings – this could effect the future and have the person result to substance abuse

Features of family members:

  • Enabler: utilizing Freuds coping mechanism, justifying and rationalizing things, keeping alcohol and saving some for later but hiding the alcohol throughout the day

- Dependency: Allowing individual to stay at home and allowing them to drink

Alcoholics should stay away from other alcoholics: example gf alcoholic is very educated about alcohol but she is an alcoholic as well, she is an enabler



Treatment: Rehab 30 days, individual is 2x likely to resort back to alcohol

90 day rehab is preferred because the rehab digs into what is the route cause of the problem – “why have they suppressed repressed their problems”

Rehab is voluntary, programs are to follow once rehab is complete, after rehab is over the problem doesn’t end because its easy for the individual to go back to old ways

Alcoholics may guilt trip someone to help them get their fix – Families can be referred to support groups as well to figure out how to deal with the alcoholic

Family members would often fight about the individual as one could believe that they are doing what's best vs what the other person believe what is best

12 Steps of AA:

  • Denial → Admission of Powerlessness
  • “We admitted we were powerless over alcohol—that our lives had become unmanageable.”
  • Hope → Belief in a Higher Power
  • “Came to believe that a Power greater than ourselves could restore us to sanity.”
  • Surrender → Turning Life Over to Higher Power
  • “Made a decision to turn our will and our lives over to the care of God as we understood Him.”
  • Self-Reflection → Moral Inventory
  • “Made a searching and fearless moral inventory of ourselves.”
  • Confession → Admitting Wrongs
  • “Admitted to God, to ourselves, and to another human being the exact nature of our wrongs.”
  • Readiness → Prepared for Change
  • “Were entirely ready to have God remove all these defects of character.”
  • Humility → Asking for Help
  • “Humbly asked Him to remove our shortcomings.”
  • Accountability → List of Those Harmed
  • “Made a list of all persons we had harmed and became willing to make amends to them all.”
  • Making Amends → Taking Responsibility
  • “Made direct amends to such people wherever possible, except when to do so would injure them or others.”
  • Continuous Reflection → Ongoing Self-Assessment
  • “Continued to take personal inventory, and when we were wrong, promptly admitted it.”
  • Spiritual Growth → Prayer and Meditation
  • “Sought through prayer and meditation to improve our conscious contact with God, as we understood Him, praying only for knowledge of His will for us and the power to carry that out.”
  • Service to Others → Spreading the Message
  • “Having had a spiritual awakening as the result of these steps, we tried to carry this message to alcoholics and to practice these principles in all our affairs.”

Substance abuse: relapse may happen, rehabs tell them to keep it pushing but don’t look at it like a failure

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Alcohol Dependence

Three patterns of use varies from person to person

Drinking large amounts every day

Binge drinking for weeks followed by abstinence

Binge drinking every weekend

People with ETOH dependence can drink with control and at other times, they cannot control drinking behaviour. As the course of alcoholism continues, there may be behaviours such as starting the day off with a drink, sneaking drinks through the day, gulping alcoholic drinks, shifting from one alcoholic beverage to another, and hiding bottles at work and at home.

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Effects of Alcohol

  • Central Nervous System (CNS) depressant

Stimulates GABA system; increases serotonin & dopamine; inhibits glutamate in both ways, the outcome is depression of the CNS

Short-term

Blood Alcohol Content (BAC)

0.02 = Pleasant feeling, well-being

0.05 = Giddiness, lowered inhibitions & impaired judgment

0.08-0.10 = Legal limit of intoxication; incoordination, speech problems, visual & thought impairment

0.20 = Brain motor area depression causes staggering, easily angered, shouting

0.30 = Confusion, stupor

0.40 = Pass out (lose consciousness), coma

0.50 = Death

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Effects of Alcohol (cont.)

Short-Term Effects

Happy, lose inhibitions

Poor judgment, poor concentration

Impaired sexual functioning

Long-Term Effects

Preoccupied with drinking; secretive

Anxiety, perhaps hallucinations

Blackouts, amnesia for events that occurred during or immediately following the drinking period

Destroys brain cells, poor nutrition

Cirrhosis (1:10 excessive drinkers)

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Physiological Complications
of Alcohol Dependence

  • Low-grade hypertension
  • Liver cirrhosis
  • Vitamin deficiencies
  • Fetal Alcohol Syndrome (FAS or FAE)
  • Wernicke’s encephalopathy
  • Korsakoff’s psychosis
  • Alcohol-induced dementia

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Alcohol Intoxication

  • Accidents or falls that may cause contusions, sprains, fractures, and facial or head trauma
  • Disorientation
  • Irritability
  • Labile emotions
  • Lack of coordination
  • Lack of inhibition
  • Loud and frequent talking
  • Nausea
  • Poor judgment
  • Short attention span
  • Slurred speech
  • Staggering
  • Violent behaviors
  • Vomiting
  • Unconsciousness, coma, respiratory depression, and death

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Alcohol Withdrawal Syndrome (AWS)

  • Typically begins 6-8 hours after last drink

Anxiety

Autonomic hyperactivity: sweating, increased heart rate,…

Insomnia

Irritability

Nausea

Sweating

Tremor

Can even lead to grand mal seizures (6-48 hours) (controlled with benzodiazepines)

Intermittent auditory, tactile or visual hallucinations, and/or illusions (12-48 hours) (misinterpretation of external stimuli; i.e., looking at a cord on the floor and thinking you are seeing a snake)

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Alcohol Withdrawal Delirium (cont.)

  • Psychoses associated with alcoholism

Alcohol Withdrawal Delirium (DTs)- usually occurs on days 2 & 3 (48-96 hours) but may appear as late as 14 days after last drink

Agitation

Acute fear

Confusion

Diaphoresis

Disorientation for time and place

Extreme suggestibility

Hypertension

Perspiration, fever, rapid & weak

heartbeat

Tachycardia

Tremors of hands, tongue, & lips

Vivid hallucinations

Coated tongue, foul breath

Death may result from collapse

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Alcohol Withdrawal Delirium (cont.)

  • Alcohol Dementia

Characterized by impaired abstract thinking and judgment, personality changes, and impaired memory. This is often seen in chronically heavy drinkers.

  • Wernicke’s Encephalopathy

Characterized by ataxia (lack of coordination), abnormal eye movements, and confusion. These symptoms results from thiamine deficiency.

  • Korsakoff’s Psychosis

Caused by toxic effects of alcohol on glutamate transmission necessary for memory storage

Inability to retrieve long-term memory of events or retain new information

Confabulation- as they try to fill in gaps of memory

  • Wernicke’s Encephalopathy
  • Characterized by ataxia (lack of coordination), abnormal eye movements, and confusion. These symptoms results from thiamine deficiency.
  • Korsakoff’s Psychosis
  • Caused by toxic effects of alcohol on glutamate transmission necessary for memory storage
  • Inability to retrieve long-term memory of events or retain new information
  • Confabulation- as they try to fill in gaps of memory

Wernicke’s Encephalopathy: movement, if it gets worse then youll get korsakoffs, ataxia (staggering gate)

Korsakoff’s Psychosis:

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Treatment & Outcome (cont.)

  • Biological approaches

Detoxification

Benzodiazepines

Are the medications of choice as they decrease withdrawal symptoms by preventing CNS hyperexcitability and prevent seizures (i.e., Librium)

Thiamine (Vitamin B1)

Are given during alcohol withdrawal to decrease the rebound effect of the nervous system (prevents or treats Wernicke’s and Korsakoff’s syndrome) as it adapts to the absence of alcohol

Vitamin B12 and folic acid for nutritional deficiencies

Rehabilitation

Antabuse (Disulfiram)

Antabuse inhibits aldehyde dehydrogenase (ALDH) and leads to an accumulation of acetaldehyde if alcohol is ingested. Reaction occurs within 5 to 10 minutes and may last from 30 minutes to several hours.

Symptoms include: flushing, nausea and copious vomiting, thirst, diaphoresis, dyspnea, hyperventilation, throbbing headache, palpitations, hypotension, weakness

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Avoid anything with alcohol: mouthwash, cough medicine, hand sanitizer - if it touches the skin the pt will have a bad reaction

- More on next slide

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Treatment & Outcome (cont.)

Medication Teaching of Antabuse (Disulfiram): avoid all exposure to alcohol and substances containing alcohol, including food, liquids, and substances applied to the skin (i.e., ETOH swabs, mouthwash, cough syrups, shaving lotion, nail polish remover, and cologne)

Naltrexone (ReVia) and Acamprosate (Campral)

Decrease craving for alcohol and narcotics and lower the relapse rate

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Opiates

  • Addictive: Concerns led to the Harrison Narcotic Act in 1914 to control use
  • Administration routes: IV (“mainlining”), snorted or smoked

Low doses – Euphoria, drowsiness, and slow breathing

High doses can be fatal

Withdrawal symptoms can be lasting and severe

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What effects is the client trying to achieve?

What are they trying to escape? Theyre underlying emotions and reliality

Once the medication wears off they go back to reality and feel worse whoch then creates dependency because they will take more

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Opiate Intoxication

  • When injected IV levels rise rapidly giving a brief, intense sensation called a rush or thrill
  • This is followed by a longer-lasting period called euphoria (a high, sense of calmness)
  • Continued use decreases the body’s production of endorphin & enkephalin, resulting in a very low tolerance of pain and discomfort during withdrawal

Can be snorted and injected

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Opiate Intoxication (cont.)

  • Opioids depress respiration and decrease GI motility

To treat overdose give IV narcan (narcotic antagonist, 0.4-2mg) to reverse respiratory depression & coma

  • Even more dangerous if used in combination with other substances

People who use cocaine use heroin in combination because cocaine loses its effects of euphoria quickly and heroin maintains it

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Family members may bring in the substance as they are enablers

Overdose treatment: Narcan

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Opiate Withdrawal

  • Withdrawal from short-acting drugs vs. long-acting drugs

Short-acting drugs (i.e., heroin) occur within 6-12 hours after the last dose, peak within 1-3 days, and gradually subside over a period of 5-7 days

Longer-acting drugs (i.e., methadone) withdrawal symptoms begin within 1-3 days after the last dose and are complete in 10-14 days

Aches, agitation, anxiety

Runny nose, teary eyes, perspiration

Chills vs. sweats, vomiting, diarrhea, cramps

Back pain, severe headache, tremors

Dehydration, can lose weight

Methadone as a treatment of choice for heroin

Withdrawal: flu like symptoms – Aches, agitation, anxiety, Runny nose, teary eyes, perspiration, Chills vs. sweats, vomiting, diarrhea, cramps, Back pain, severe headache, tremors, Dehydration, can lose weight

Methadone – nurse needs to confirm with clinic that pt is getting their methadone from then dr will prescribe methadone

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Complications

  • Poisoning because heroin is often “cut” with substances that may contain impurities to increase the quantity for sale
  • Addicts may use unsanitary needles

High risk for hepatitis

HIV infection

AIDS

Liver problems

Kidney failure

Suboxone: opioid antagonist – only used for opiates

Helping cover the cravings the opiates give

Review veins – cellulitis could happen

Needle exchange programs: because substance abuse users will get their drug anyway, curve HIV/AIDs by providing clear needles

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  • Causal factors in opiate abuse

NO SINGLE PATTERN!

Pleasure is a common reason given (81%)

Addiction associated with pain relief

Addiction associated with psychopathology

  • Treatment & Outcome

Detoxification

Methadone

Purpose of methadone is to reduce the craving to ward off withdrawal symptoms. Provides a longer-acting narcotic that is a substitute for heroin.

Buprenorphine

Under-the-tongue lozenge acts like extra-mild methadone at low doses

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Sedative, Hypnotic, or Anxiolytic Substance Use Disorders:
An Overview

  • The Nature of Drugs in This Class

Sedatives – Calming (i.e., barbiturates = Amytal, Phenobarbital, Seconal)

Hypnotic – Sleep inducing (i.e., Ambien, Lunesta, Restoril)

Anxiolytic – Anxiety reducing (i.e., benzodiazepines = Ativan, Valium, Xanax)

  • Effects Are Similar to Large Doses of Alcohol

Combining such drugs with alcohol is synergistic. Cause significant CNS depression (decreased BP, HR)

  • All Influence the GABA Neurotransmitter System causing significant CNS depression

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Alcohol and pills are typically abused together

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Sedatives

Barbiturates & Benzodiazepines

Powerful CNS depressant

Medical uses = calming, induce sleep

After short time, feel relaxed then drowsy

Excessive dose is lethal

Physically addictive

Effect: depression, drowsiness, euphoria, labile emotions, irritability, impaired attention and working memory loss, impaired comprehension, mood swings, motor incoordination, sluggish, slow speech, thinking is “fuzzy”

Brain damage may occur if prolonged use

Associated with more overdoses & suicides than any other drug

Cold clammy skin

Weak & rapid pulse

Shallow respirations

Coma & death (increases when combined with ETOH)

Main take away:

The more that is used the higher the tolerance

Withdrawls – these meds cannot be stopped abruptly because they can die from seizures – pt needs to be in a controlled enviorment to deal with the withdrawal effects

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Causal factors in barbiturate dependence

Many experiment, most don’t become dependent

“Silent abusers”

Combining with alcohol can be deadly

The drugs potentiate one another

Treatment & Outcome

Withdrawal symptoms more dangerous than for opiates (6 to 8 hours of last dose to greater than a week)

Altered perceptions, delirium, hallucinations

Agitation, anxious, apprehensive, insomnia

Coarse tremors in hands, face

Weakness, nausea/vomiting, lose weight

Rapid heart rate, high blood pressure

Possible convulsions

If individuals have been taking high doses for a long period of time, WD process should be medically supervised

Abrupt cessation can lead to seizures thus carefully titrate downward until withdrawal process is complete

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Stimulants:
Cocaine Use Disorders (cont.)

Cocaine

Causes vasoconstriction when snorting through the mucous membranes may cause ulceration of the nasal mucous membranes and may lead to perforation of the septum and loss of the sense of smell

Short half-life: Wears off quickly

Makes it less efficient than if smoked as crack

Stimulates cortex inducing excitement & sleeplessness

Initial rush of euphoria lasts 10-20 min., feeling confident & content

May hallucinate with chronic use (some tolerance)

Use can be fatal

Crack (looks like small “rocks”)

Immediate high & intense addiction

freebase cocaine, purified, 6-7 sec. for the drug to reach the brain, high lasts only 2-5 min., and the crash is more severe

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Cocaine: fast acting and doesn’t last that long in system, typically combined with heroin

Who would abuse cocaine: people in the entertainment industry

Appetite: suppresses

Increases confidence

Cocaine can be very expensive

Snorting is common route – crosses the blood brain barrier quicker – watch for cardiac

  • As a nurse you would observe the nose passageways, bloody noses, irritation

    Eyes:
  • Pin point pupils

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Stimulants:
Cocaine Use Disorders (cont.)

Cocaine: Comorbid with alcohol abuse

Drug Addiction Unit of the Montreal General Hospital: 29% of patients were abusing cocaine & alcohol

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Stimulants:
Cocaine Use Disorders (cont.)
Intoxication

Anger

Combativeness

Euphoria, mental alertness

Rapid heartbeat

Dilation of pupils

Changes in blood pressure, pulse, respiration

Increased energy

Feelings of self-confidence

Tension, fatigue, shyness disappears and the person becomes more talkative and playful (lasts 10-20 min.) Large doses can lead to paranoia & violent behaviour

Seizures, respiratory depression, and cardiac arrhythmias

People with low self esteem may take this, more energy, agitates the patient more

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Cocaine Withdrawal

  • Following cocaine use, the intense pleasure is replaced by equally unpleasant feelings. Referred to as a rebound dysphoria or “crash.” Negative reinforcement occurs when person experienced crash takes more cocaine to overcome dysphoria.
  • Fatigue
  • Vivid dreams
  • Insomnia or hypersomnia
  • Increased appetite
  • Psychomotor agitation or retardation

Treatment is dependent on what the patient is experiencing

Insomnia: benzo may be prescribed

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Cocaine Withdrawal (cont.)

  • Some try speedballing, in which cocaine is mixed with heroin and injected IV. High reached in seconds. Appeal of speedballing is that heroin decreases the unpleasant jitteriness and crash from cocaine.
  • Treatment of withdrawal

Lidocaine or propranolol IV for ventricular dysrhythmias

Seizure medications

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Stimulants:
Amphetamine Use Disorders

  • Effects of Amphetamines

Produce elation, vigor, reduce fatigue

Effects are followed by extreme fatigue and depression

  • Ecstasy and Ice

Produces effects similar to speed, but no “comedown”

2% of college students report using Ecstasy

Both drugs can result in dependence

  • Amphetamines stimulate CNS by

Enhancing release of norepinephrine and dopamine

Reuptake is subsequently blocked

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Substance induced dementia could happen, blackouts, confabulation

Brain damage could be irreversible

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Abusing drugs, could:

Age the person

Some substance could be acidic: burns the face

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Some substances could erode the teeth

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Treatment & Outcome for Amphetamine Abuse

Withdrawal usually painless

Enhanced appetite, exhaustion, excessive need for sleep, fatigue, unpleasant dreams,

Cold turkey withdrawal can cause cramping, nausea, diarrhea, convulsions if use was chronic

Treatment: supportive treatment, suppresses the appetite: now they may have an increased appetite

Hypertensive? Beta blockers or another hypertensive med may be given

Seizure risk: smalla mount of seizure med may be given if pt is at risk

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Stimulants:
Nicotine Use Disorders

  • Effects of Nicotine

Stimulates nicotinic acetylcholine receptors

Stimulant that has direct reinforcing effects on DA in the nucleus accumbens, the reward center of the brain

Results in sensations of relaxation, wellness, pleasure

Nicotine is highly addictive

Relapse rates equal those for alcohol and heroin users

  • DSM-IV-TR Criteria for Nicotine Withdrawal Only

Psychological symptoms

Physiological symptoms

  • Cessation causes withdrawal symptoms (i.e., anxiety, headaches, inability to concentrate, insomnia, irritability, overeating, and restlessness)

TX: nicotine patches

Nicotine patches could be given to assist in weening off

Physiological complication: lung cancer, esophageal cancer, oral cancer, second hand smoking, stains teeth (yellow)

Cigarettes aren’t cheap

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Nicotine

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The first dose of nicotine in the morning brings the most pleasure: because you were sleeping you were off the nicotine for a long time, dopamine goes down when you sleep, dopamine will go up once you smoke the cigarette bc it brings the indivisual the most joy

dependency

  • C – Cut down
  • “Have you ever felt you should cut down on your drinking?”
  • A – Annoyed
  • “Have people annoyed you by criticizing your drinking?”
  • G – Guilty
  • “Have you ever felt guilty about your drinking?”
  • E – Eye-opener
  • “Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hangover (eye-opener)?”

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Stimulants:
Caffeine Use Disorders

  • Effects of Caffeine – The “Gentle” Stimulant

Found in tea, coffee, cola drinks, and cocoa products

Blocks the reuptake of the neurotransmitter adenosine resulting in mental alertness

Small doses elevate mood and reduce fatigue

Used by over 90% of Americans

Regular use can result in tolerance and dependence

Intoxication from caffeine usually occurs following consumption in excess of 250 mg

Complications- increased anxiety, jittery, or shaky, insomnia, dependency and withdrawal can occur

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Can experience dependency

Can be costly

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Hallucinogens:
An Overview

  • Nature of Hallucinogens

Examples include LSD, PCP, Mescaline (Peyote)

Heighten visual perception, produce delusions, paranoia

Popular in nightclubs, raves, or large social gatherings

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Young age group

These make the pt super psychotic

These substances are very dangerous: delusions, flashback

Safety is very important for these pts

Restraints may be necessary

Drug screen only tells if positive or negative doesn’t give how much

Nurses shouldn’t go into these pts room by themselves esp if giving IM – after giving IM nurse turned her back and the pt pushed her down and was about to rape her

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Hallucinogens:
An Overview (cont.)

  • One of the dangers is a “bad trip”: during which the person is in a psychotic state and terrified by perceptual changes, hallucinates, severe anxiety, paranoia, loss of control, or insane
  • The 2nd type of reaction is the “flashback” previous hallucinogenic experiences that occur in the absence of the substance

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Hallucinogens

LSD & PCP (most potent hallucinogen)

8 hours of altered sensory perception, labile emotion, depersonalization, derealization

Effect peaks within minutes to a few hours

Sensory-perceptual distortion

Belligerence, assaultiveness, impulsiveness, unpredictability, psychomotor agitation

Fear of losing one’s mind

Illusions

Insomnia

Paranoia

Psychotic delusions & hallucinations

tremors

Vivid visual images

VS increased

Tolerance tends to be rapid

Withdrawal symptoms are uncommon

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Pt is very assaultive, unpredictable,

Whether their intoxicated or withdrawing

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Cannabis

  • Marijuana & hashish: smoked or taken orally
  • THC (tetrahydrocannabinol): active ingredient of cannabis. Acts on cardiovascular and CNS
  • Most commonly used illegal drug

60 million people have tried it

Effects

Mild euphoria, relaxation, drifting sensation

Time distortion, moderate increase in heart rate

Slowed reaction time, redness of the eyes, contraction of pupils

Dry mouth, increased appetite

  • Produces a greater amount of “tar” than its equivalent tobacco

Cannabis smoke contains more carcinogens

  • Withdrawal effects are dose related

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Gateway drug

Pts may self medicate with pain management

Cancer pts: can increase appetite

Has benefits with medical supervision

Marijuana can make people psychotic

Can cause dementia

Eyes: redness

Euphoric

Relaxed

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Cannabis (cont.)

  • Medical uses: Patients undergoing chemotherapy, suffering from AIDS, glaucoma, MS…
  • Several states have approved marijuana for medical purposes. It appears to be a more potent antimetic drug.
  • Gateway drug?

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Other Drugs of Abuse:
Anabolic Steroids

  • Nature of Anabolic-Androgenic Steroids

Steroids are derived or synthesized from testosterone

Used medicinally or to increase body mass and improve physical appearance

Users may engage in cycling or stacking (i.e., begins with low doses and slowly increases the doses and then slowly decreasing the doses

Steroids do not produce a high

Long-term mood disturbances and physical problems known as roid rage, with dramatic mood swings, manic-like episodes and a tendency toward aggressive behavior and violence.

Women using anabolic steroids may increase muscle mass, develop a deeper voice, absent menses

Athletes typically abuse this

People trying to bulk up may take this

Use of marijuana and anabolic steroids : referred to an endochronoligist because it can effect their hormones

If abusing for a long time – this needs to be tapers down

Long-term mood disturbances and physical problems known as roid rage, with dramatic mood swings, manic-like episodes and a tendency toward aggressive behavior and violence.

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Other Drugs of Abuse: Inhalants

  • Nature of Inhalants (CNS depressants)

Abusers: boys between 10-15 years old (also multidrug users)

Found in volatile solvents

Examples include air fresheners, dry cleaning fluid, spray paint, hair spray, paint thinner, gasoline, nitrous oxide

Breathed into the lungs directly. Fumes are inhaled directly from an open container or from a surface upon which the substance has been applied (sniffing), from a plastic bag (snorting) or from inhalant-soaked rag next to the mouth or nose (huffing), or substance is placed in a paper or plastic bag and inhaled (bagging)

Such drugs are rapidly absorbed

Children

Inhalant: glue, paint, spray, aerosols, white out

Going across the blood brain barrier, nose bleeds and serizers can be of concern

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Other Drugs of Abuse:
Inhalants (cont.)

  • Effects

Euphoria, giddiness, impaired judgment, lethargy, lightheadness, loss of contact with reality, slurred speech, tingling, unsteady gait

  • Produce tolerance
  • No known withdrawal symptoms
  • Complications

Nose bleeds

Can cause respiratory tract irritations, CNS damage, hepatitis, liver damage,…

Sudden sniffing death: Arrhythmia or apoxia

Multiple organ damage: CV and pulmonary death

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Characteristics of Substance Abusers

Denial

Rationalization

Justification

Intecultaion

- Freud

First step is admistting you have a problem

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Effects on the Family

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Effects on the Family (cont.)

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Nursing Process

Assessment

  • Assess for each substance
  • Age begun
  • Method of use
  • Amount and frequency of use
  • Most recent use
  • Withdrawal symptoms in the past
  • Setting and circumstances of use
  • Benefits of use
  • Proportion of income or savings spent on drugs
  • Financial consequences of drug use
  • Relationship, vocational, social problems associated with use

Things cant be sugar coated with these patients

How much is being consumed?

What type?

How many a day?

When are you drinking?

Where are you drinking?

Are you drinking while driving? Have you ever had a DUI

What problem have you had while drinking?

Any problems they have?

What does this substance do for you?

Whats the feeling?

Have you had any serizers or black outs?

Tremors or shakes?

Are you doing it in front of other individuals?

Where are you getting the money for it?

Are you getting in trouble with the law?

How much of your check are you spending on the substance?

Depending on the substance

Have you ever had nose bleeds

All of these questions would be shown to pt to get them passed this denial

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Nursing Process (cont.)
Physical Assessment

  • Skin and scalp

Ecchymosis, lacerations, scars, bruises, dermatitis, spider angiomas, edema

  • Head

Facial edema or a “puffy face” with flushed cheeks and nose

  • Eyes

Icterus in the sclera from hepatitis or cirrhosis

  • Ears

Infection

  • Mouth

Lip peeling or fissures due to vitamin B deficiency, gum disease

  • Neck

Cardiomypoathy and CHF causing increased venous pressure, which results in distended juglar veins

  • Chest

TB, pneumonia

  • Abdomen

Fluid retention and tense glistening skin resulting from ascites, hepatitis, hemorrhoids, esophageal varices

Physical Assessment for alcholics example:

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Concomitant Disorders/
Dual Diagnosis of Mentally Ill
Chemical Abuser

  • Clients must be assessed for dual diagnosis, the presence of substance abuse with a concurrent psychiatric disorder
  • A dual diagnosis indicates one of three things:

Two independent disorders occur together

Substance abuse caused the other mental disorder

The person with the mental disorder uses substances in an effort to self-medicate and feel better

*

Nurse wants to find out when they started using

Abusing while young?

Mental health issues?

If patient says no – primary substance abuse problem

Treatment? Rehab? NA? AA?

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Nursing Diagnosis

  • Ineffective denial related to weak, underdeveloped ego
  • Ineffective coping related to inadequate coping skills and weak ego
  • Imbalanced nutrition less than body requirements/fluid volume deficit related to drinking or taking drugs instead of eating
  • Risk for infection related to malnutrition and altered immune condition
  • Low self-esteem related to weak ego, lack of positive feedback
  • Deficient knowledge (effects of substance abuse on the body) related to denial of problems with substances evidenced by abuse of substances

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Nursing Outcomes

  • The client will:

Abstain from alcohol/drugs

Express feelings openly and directly

Accept responsibility for own behavior

Practice nonchemical alternatives to deal with stress or difficult situations

Establish an effective after-care plan

*

Nursing Outcomes

  • Short-term Goals

Identifying and initiating treatment for patients at risk

Encouraging abstinence

Promoting attendance at meetings or other counseling programs

Involving family, community, and employment resources

  • Long-term Goals

Restoration of self-esteem

Resolution of substance-related social problems

Improvement in physical health issues

Long-term sobriety

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Nursing Process (cont.)

*

EKG

Tylenol or aspirin levels will be checked if suspected overdose

Cardiac will be reviewed: Troponin

Marijuana stays in the the body for up to 45 days

Blood alcohol levels: could determine how long the client will stay in the hospital

Blood alcohol should be repeated and have it be less than 10 or 0

25 – 30 points an hour depends on BMI

What are the blood alcohol levels:

Vital signs: keep pt in low stimulating environment

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Psychosocial Treatment of Substance-Related Disorders

  • Inpatient vs. Outpatient Care

Inpatient treatment occurs in the ED and on acute care inpatient units

Hospitalization is appropriate for those (1) at risk for severe withdrawal syndromes, (2) those who are psychiatrically disabled, (3) those who are a danger to themselves or others, and (4) those who have not responded to less intensive treatment efforts

Residential treatment usually lasts 7-21 days and offers a safe and structured environment for those who lack social and vocational skills and drug-free social supports to be abstinent in a less restricted setting

What is the best program for the patient?

Substance abuse is mostly voluntary unless a judge admits them (danger to self or others)

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Psychosocial Treatment of Substance-Related Disorders (cont.)

  • Drug rehabilitation

Is the recovery of optimal health. It views chemical dependence as a chronic, progressive, and often fatal disease. The responsibility is on the clients, and any attempt to shift responsibility to others, such as family, is confronted directly. Recovery is considered a lifelong, day-to-day process and is accomplished with the support from peers with the same addiction

i.e., 12-step program (AA and/or NA)

  • Behavioral interventions
  • Cognitive therapy

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AA and/or NA: lifelong

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Psychosocial Treatment of Substance-Related Disorders (cont.)

  • Family therapy and education

Nature of the illness

Effects of substances on the body

Ways in which use of substance affects life

Management of the illness

Support services

  • Group therapy and early recovery

Clients learn to accept themselves as recovering individuals and help themselves while helping others

  • Individual therapy
  • Psychoeducation groups

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Psychosocial Treatment of Substance-Related Disorders (cont.)

  • Complete Abstinence vs. Sobriety as Treatment Goals

Abstinence is merely stopping the intake of the drug; it does not imply that any other behaviors have changed

Sobriety implies that not only have these individuals stopped using the drug, but they have also achieved a centered or balanced state. Sobriety is the overall goals of drug rehabilitation.

  • Community Support Programs

Alcoholics Anonymous and related groups

Seem helpful and are strongly encouraged

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Motivation for Change

  • Key predictor of whether an individual will change his/her substance abuse

Clients must overcome denial and recognize the significance of the substance dependence on his or her life

Involves recognizing problem, correlating problems with substance abuse, and searching for a way to change and then changing

  • Motivational interviewing seeks to elicit self-motivational statement from patients, supports behavioral change and creates a discrepancy between the patient’s goals and continued alcohol and other drug use

*

Patient would most likely relapse

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Transtheortical Model of Change

Precontemplation

Contemplation

Determination

Action

Maintenance

Relapse

Permanent exit

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Reality Confrontation

  • Therapeutic strategy that promotes the person’s experience of the natural consequences of one’s behavior
  • Learning from previous behavior
  • Guidelines for establishing interactions

More assertive in communication – which will upset the pt but the pt needs to understand their actions

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Evaluation

  • Evaluation involves reassessment to determine whether the nursing interventions have been effective in achieving the intended goals of care