Legalization of Marijuana (Support Legalization of Marijuana for medical and recreation use)

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SAMPLEANNOTATEDBIBLIOGRAPHYENTRYSummer2020.pdf

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Dr. Randall Watson

English 1302

25 June 2017

Legalizing Marijuana for Medical Use: An Annotated Bibliography

Backes, Michael. Cannabis Pharmacy: The Practical Guide to Medical Marijuana. New

York, Black Dog & Leventhal, 2014.

Author Michael Backes, is a respected expert in his field and head of research at

California’s first research based medical cannabis collective, Abatin Wellness

Center. The book explains how cannabis acts in the human body including how it

affects the endocannabinoid system, which plays a large role in medical use.

Backes has prepared a guide for 29 illnesses to which medical marijuana can be

effective in treating ailments such as chronic pain, multiple sclerosis, Alzheimer’s

disease, and chemotherapy associated nausea, to name a few. The book

includes dosage control and cannabis varieties, written clearly for practical use

and understanding. To lend credibility, the book includes a foreword by Harvard

educated physician and alternative medicine guru Andrew Weil.

Caffarel, María M., et al. "Cannabinoids Reduce Erbb2-Driven Breast Cancer

Progression through Akt Inhibition." Molecular Cancer, vol. 9, Jan. 2010, pp.

196-206. EBSCOhost.

The authors and researchers at BioMed Central conducted a research study to

test the effectiveness of cannabinoids on reducing ErbB2-driven breast cancer

through Akt inhibition. ErbB2-positive breast cancer is aggressive and has a low

chance of responding to traditional therapies. Specific therapies which target the

phenotypes do exist, however the patients are likely to relapse, which is why

they seek alternate therapies. In this study, histological analysis of MMTV-mice

indicated that when delta 9-tetrahydrocannibol was used as a therapy, cancer

cell proliferation was inhibited and cancer cell apoptosis was induced. The study

found that 91% of ErbB2-positive tumors expressed the cannabinoid CB2

receptors. In relation to the FDA’s need for research, this study shows valid

evidence to support that cannabinoids are effective cancer based therapies.

“Cannabinoids Testimonials.” Cancer Survivors Network, csn.cancer.org/node/283635.

Accessed 30 Apr. 2017.

The American Cancer Society has dedicated a page to cancer survivors and their

testimonials on cannabinoids. Some have posted links to research based studies

and journals, while others simply share testimonials. The most powerful being a

woman who claims she was diagnosed with stage 4 cancer and given 6-9 months

to live back in 2010. She attributes self-treatment of cannabis to being alive and

scans showing no progression of the disease. While testimonials cannot replace

clinical trials, it is important to look at success stories of in palliative care patients

such as this and relate them to the medicinal benefits of marijuana because it is

the closest thing to human testing that currently exists.

Dougherty, Elizabeth. “Medicine Gone Rogue.” Harvard Medical School, 6 July 2016,

dbmi.hms.harvard.edu/news/medicine-gone-rogue. Accessed 30 Apr. 2017.

The authors, researchers, and engineers at Harvard Medical School collaborated

to discuss Rogue Therapeutics which is a new model of medicine intended to

challenge outdated, conventional wisdom. The unconventional therapies include

genetic testing, bionic pancreas’, and of course, cannabis therapy. Precision

medicine panelists including rogues and traditionalists discuss the possible

consequences that legalization will have given its lack of regulation by the FDA.