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BIOLOGY AND BEHAVIOR

Chapter 2

PSYCHOLOGY DEBORAH M. LICHT MISTY G. HULL COCO BALLANTYNE

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Biology and Behavior

Brandon Burns poses for a photo at the Marine Corps Recruit Depot in Parris Island, South Carolina, in the fall of 2003. The following year, he was shot in the head by an enemy sniper in the Battle of Fallujah.

Doctors concluded that some parts of his brain were no longer viable. “They removed part of my skull and dug out the injured part of my brain,” and now, Brandon says, “one third of my brain is gone.”

What were the consequences of his injury?

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A Complex Communication Network

Nervous system

A communication network that conveys messages throughout the body, using electrical and chemical processes

Brain

An intricate, dynamic connections web that provides the power to think and feel in ways that differ from and are more complex than in other organisms

Contains between 86 and 100 billion nerve cells that can each typically communicate with other cells through a system of an estimated 100 trillion links

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The Last Frontier: From Bumps to Brain Scans (part 1)

Neuroscience

Involves the study of the brain and nervous system

Draws upon multiple disciplines, including psychology

Biological psychology

A subfield of psychology

Focuses on how the brain and other biological systems influence human behavior

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The Last Frontier: From Bumps to Brain Scans (part 2)

EARLY

Franz Joseph Gall (1757−1828)

Early ”brain” scientist and neuroanatomist

Phrenology

Pierre Flourens (1794−1828)

Ablation and physiology

Explained that areas of the brain might have particular functions

CONTEMPORARY

Horikawa and colleagues; Hsu and colleagues

Observing the brain as it sleeps, reads, tells lies

Max-Planck-Gesellschaft

Manipulating activity of individual brain cells

Optogenetics

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Ways to Study the Living Brain

Looking at brain STRUCTURE

Computerized axial tomography (CAT)

Magnetic resonance imaging (MRI)

Watching brain FUNCTION

Electroencephalogram (EEG)

Positron emission tomography (PET)

Functional magnetic resonance imaging (fMRI)

What’s next? MAKING CONNECTIONS

Diffusion spectrum imaging (DSI)

See INFOGRAPHIC 2.1 for additional information.

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Can you identify the structure of a typical neuron?

Cell body

Dendrites

Axon

Terminal buds

Nodes of Ranvier

Myelin sheath

Synapse

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The Neuron

The neuron, the basic building block of the nervous system, has three main components: (1) a cell body, which contains vital cellular structures; (2) bushy dendrites that receive messages from neighboring neurons; and (3) a long, thin axon that sends messages to other neurons through its branchlike terminal buds. James Cavallini/Science Source.

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Holding It Together: Glial Cells

Glia to the rescue

A scanning electron micrograph shows neurons (green) and glia (orange)

Glial cells serve as the “glue” of the nervous system, providing cohesion and support for the neurons. Some classes of glial cells

Microglia

Astrocytes

Schwann cells

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Neurons and Neural Communication (part 1)

PROCESSES INSIDE THE NEURON

The neuron is surrounded by and filled with positive and negative electrically charged ions.

The difference in sum of the positive and negative charges determines charge overall.

Two processes direct ion flow into and out of the cell:

Diffusion

Electrostatic pressure

The summation of negatives and positives produces the voltage neuron difference.

Neurons and Neural Communication (part 2)

PROCESSES INSIDE THE NEURON

A selectively permeable neuron membrane allows selectively ion movement in and out of its channels.

Positive sodium ions

Negative protein ions

Ion passage through the membrane plays an important role in how neurons transmit information.

Here’s what is going on when the neuron is not active: The negative protein ions are only on the inside of the cell, but they are attracted to the excess positive charge outside and move toward the membrane. Because the protein ions (–) are too big to get through the membrane, the inside of the neuron is negatively charged (Infographic 2.2). Although there are some positive potassium ions inside the neuron, the concentration of sodium ions (+) outside the cell is much greater than that inside. As a result, sodium ions on the outside are attracted to the membrane (because of diffusion and electrostatic pressure).

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Biology and Behavior: Processes Inside the Neuron (part 1)

COMMUNICATION WITHIN AND BETWEEN

Resting potential

Electrical potential of cell at rest

Solutions on either side of the membrane wall come into equilibrium, with a slightly more negative charge inside.

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Biology and Behavior: Processes Inside the Neuron (part 2)

COMMUNICATION WITHIN AND BETWEEN

Action potential

Involves spike in electrical energy that passes through the axon of a neuron, the purpose of which is to convey information

Is all-or-none

Every time a segment of the axon fires

Positive sodium ions flood in from the outside of the cell, while the prior segment returns to its resting potential, all along the length of the axon to its end.

How does a neuron convey the strength of a stimulus?

By (1) firing more often, and (2) delivering its message to more neurons. Consider a loud scream and a quiet whisper. The loud scream is a stronger stimulus, so it causes more sensory neurons to fire than the quiet whisper. The loud scream also prompts each neuron to fire more often.

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Biology and Behavior: Processes Inside the Neuron (part 3)

COMMUNICATION WITHIN AND BETWEEN

Excitatory signals

Occur when enough signals combine and sending neurons signal the receiving neuron to pass along the message

Inhibitory signals

Inhibit neuron from releasing a signal through the axon

All-or-none

Action potentials are all-or-none.

The neuron conveys stimulus strength by firing more often and delivering its message to more neurons.

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Biology and Behavior: Processes Inside the Neuron (part 4)

The myelin sheath insulates and protects the tiny spikes in electricity happening inside the axon.

Action potential “skips” over the segments of myelin, hopping from one node to the next, instead of traversing the entire length of the axon.

Myelin

Protein that envelops and insulates the axon, facilitating faster transmission of the impulse

Action potentials may travel as fast as 268 miles per hour through a myelinated axon (Susuki, 2010). Myelin is a protein that envelops and insulates the axon, facilitating faster transmission. The action potential “skips” over the segments of myelin, hopping from one node of Ranvier to the next (see small space in the center), instead of traversing the entire length of the axon. Jean-Claude Revy, ISM/Phototake.

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Biology and Behavior: Communication Between Neurons

Neurotransmitters

Chemical messengers that neurons use

Receptor sites

Location where neurotransmitters attach on the receiving side of the synaptic gap

Reuptake

Occurs when neurotransmitters are reabsorbed by the sending bud

Diffusion

Occurs when neurotransmitters are not reabsorbed and drift out of the synaptic gap

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Biology and Behavior: The Synapse

The terminal bud of a sending neuron (top) interacts with a dendrite of a receiving neuron by releasing chemical messengers (neurotransmitters) into the synapse.

Once the neurotransmitters migrate across the gap and latch onto the dendrite’s receptor sites, the message has been conveyed.

See INFOGRAPHIC 2.3 for graphic presentation of communication between neurons.

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Biology and Behavior: Neurotransmitters and Behavior

NEUROTRANSMITTERS

Approximately 100 neurotransmitters have been discovered.

Neurotransmitters secreted by one neuron under certain conditions can cause neighboring neurons to fire, which can affect the regulation of mood, appetite, muscles, organs, arousal, and a variety of other functions.

See Table 2.5 for additional information about the surprising effects of neurotransmitters.

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Biology and Behavior: Neurotransmitters and Behavior (part 1)

ACETYCHOLINE

Relays messages from motor neurons to muscles, enabling movement; involved in memory

Low levels linked to Alzheimer’s disease

Too much = spasms; too little = paralysis

Potential wonder drug for disease treatment

GLUTAMATE

Makes neurons fire; central role in memory and learning

Too much = strokes; too little = symptoms of schizophrenia

GABA

Inhibits neurotransmitter firing; contributes to motor control and vision

Roles in sleep and wakefulness

Decreased with long-term alcohol use

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Biology and Behavior: Neurotransmitters and Behavior (part 2)

NOREPINEPHRINE

Has variety of effects in CNS; helps body prepare for stress

Plays important role in maintaining attention

High levels lead to over-arousal and hypervigilance

SEROTONIN

Plays key role in controlling appetite, aggression, and mood; regulates sleep and breathing

SSRIs boost effects of positive feelings

DOPAMINE

Plays role in abuse of some substances (cocaine and amphetamines)

Impacts attention, learning through reinforcement, and regulation of body movement

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Biology and Behavior: Neurotransmitters and Behavior (part 3)

ENDORPHINS

Regulates secretion of other neurotransmitter; naturally produced opioids; reduces pain and elevates mood

AGONISTS

Interfere at level of synapse; increase normal neurotransmitter activity

ANTAGONISTS

Interfere at level of synapse; decrease normal neurotransmitter activity

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The Supporting Systems: Overview of the Nervous System

The brain needs supporting infrastructure to carry out directives and relay essential information from outside.

Central nervous system (CNS)

Peripheral nervous system (PNS)

The nervous system is made up of the central nervous system, which includes the brain and spinal cord, and the peripheral nervous system.

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The Supporting Systems

SPINAL CORD

Includes bundle of neurons; Connects with the body’s muscles, glands, and organs

SPINAL CORD RESPONSIBILITIES

Receiving information from the body and sending it to the brain

Taking information from the brain and delivering it throughout the body

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The Supporting Systems: Types of Neurons

SENSORY NEURONS

Receive information about the environment from the sensory systems and convey it to the brain for processing

MOTOR NEURONS

Carry information from CNS to produce movement; provide mechanism regulated by spinal cord and the brain

INTERNEURONS

Reside in the brain and spinal cord; act as bridges connecting sensory and motor neurons

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THE SPINAL CORD AND REFLEX ARC

Without any input from the brain, the spinal cord neurons are capable of creating some simple reflexive behavior.

While the spinal reflex occurs, sensory neurons also send messages to the brain, letting it know what has happened.

This type of pain reflex includes a number of steps: (1) Your hand touches the hot pan, activating sensory receptors, which cause the sensory neurons to carry a signal from your hand to the spinal cord. (2) In the spinal cord, the signal from the sensory neurons is received by interneurons. (3) The interneurons quickly activate motor neurons and instruct them to respond. (4) The motor neurons then command your muscles to contract, causing your hand to withdraw quickly. A sensory neuron has a rendezvous with an interneuron in the spinal cord, which then commands a motor neuron to react—no brain required. We refer to this process, in which a stimulus causes an involuntary response, as a reflex arc.

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What Lies Beyond: The Peripheral Nervous System (part 1)

PERIPHERAL NERVOUS SYSTEM (PNS)

Includes all neurons not in CNS

Involves neurons that are bundled together (nerves) to carry signals throughout body

Nerves

Act as primary communication system for PNS

Supply CNS with information about body’s environment

Have two functional branches: somatic and autonomic nervous systems

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What Lies Beyond: The Peripheral Nervous System (part 2)

SOMATIC NERVOUS SYSTEM

Characteristics

Involves branch of the parasympathetic nervous system

Includes sensory nerves and motor nerves

Gathers information from sensory receptors

Controls the skeletal muscles responsible for voluntary movement

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What Lies Beyond: The Peripheral Nervous System (part 3)

AUTONOMIC NERVOUS SYSTEM

Characteristics

Regulates involuntary activity

Has two divisions involved in physiological responses to stress or crisis situations

Sympathetic nervous system

Parasympathetic nervous system

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The Sympathetic and Parasympathetic Nervous System

The autonomic nervous system has two divisions, the sympathetic and parasympathetic nervous systems. In a stressful situation, the sympathetic nervous system initiates the “fight-or-flight” response. The parasympathetic nervous system calms the body when the stressful situation has subsided.

Photo: PhotoObjects.net/Thinkstock/Getty Images.

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What Lies Beyond: The Peripheral Nervous System (part 4)

HIS BRAIN, HER BRAIN

Hardwired differently versus socially conditioned to develop certain interests and skills

GENDER SIMILARITIES AND DISPARITIES IN BRAIN ANATOMY AND FUNCTION

Differences in asymmetry of cerebral hemisphere

Higher volumes of gray matter in female brain

Gender disparities in brain networks involving social cognition and visual-spatial abilities—some may be present early in development

Could some of these differences explain why genders are drawn to different areas of study?

Female response to stress

Many women have inclination to direct energy toward nurturing and forging social bonds as a stress response.

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BACHELOR’S DEGREES AWARDED IN THE UNITED STATES

Bachelor’s Degrees Awarded in the United States

Women earn the majority (57.3%) of all bachelor’s degrees awarded in the United States. But when it comes to degrees awarded in science, math, and engineering, the numbers look very different. Why do so many fewer women receive degrees in STEM fields?

Information from the National Science Foundation, 2015.

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The Endocrine System and Its Slowpoke Messengers

ENDOCRINE SYSTEM

Hormones

Pituitary gland

Thyroid gland

Adrenal glands

Can you define each of these? How do they influence behavior and physiological processes?

Together, these glands and organs can impact: (1) growth and sex characteristics, (2) regulation of some of the basic body processes, and (3) responses to emergencies. Just as our behaviors are influenced by neurotransmitters we can’t see and action by the endocrine system are also hard at work behind the scenes.

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The Endocrine System

This system of glands communicates within the body by secreting hormones directly into the bloodstream. Photos: (left, face) Hemera/Thinkstock/Getty Images; (left, body) © Yuri Arcurs/Alamy; (right) Asiaselects/ Getty Images.

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Two Hemispheres

RIGHT BRAIN, LEFT BRAIN: THE TWO HEMISPHERES

Cerebrum

Includes largest, most highly developed part of brain

Involved in intelligence, personality, thinking, perceiving, planning and organization, language, sensation, motor functions

Divided into right and left hemispheres and linked by corpus callosum

Corpus Callosum

Includes bundle of nerve fibers

Enables left and right side brain to communicate and to work together to process information

The cerebrum looks like a walnut with its two wrinkled halves.

It contains all brain parts expect the brainstem structures.

Regions of the left and right hemispheres specialize in different activities, but the two sides of he brain are constantly communicating and collaborating. Science Source.

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The Hemispheres: Split-Brain Operation

Hemispherectomies

Exceptionally rare; last resort

Callostomies (split-brain operations)

Right and left hemisphere disconnected

MRI SCAN

Both hemispheres intact after hemispherectomy

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The Split-Brain Experiment

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The Hemispheres: Lateralization

Lateralization

Each cerebral hemisphere processes certain types of information and excels in certain activities.

Generalization

The left hemisphere plays a crucial role in language processing, and the right hemisphere plays a crucial role in managing visual spatial tasks.

But

Hemispheres constantly integrate and share information.

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The Special Roles of the Left and the Right

Handedness and language dominance

The left hemisphere controls language in most people; it does not necessarily correspond to handedness.

Areas responsible for language production and comprehension

EARLY RESEARCH

Broca’s area originally thought responsible for speech creation

Wernicke’s area originally thought responsible for comprehension

TODAY

Areas perform additional functions and cooperate with multiple brain regions

The left hemisphere handles language processing in around 95% to 99% of people who are right-handed, but only in about 70% of those who are left-handed (Corballis, 2014).

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Speak Again

Brandon works on his pronunciation in front of a mirror during a speech therapy session at the Memphis VA hospital. You can see the extent of his injury on the left side of his head. Upon awakening from his coma, Brandon could not articulate a single word. Today, he can hold his own in complex conversations.

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The Hemispheres: Language Area and the Brain

Broca’s area

Wernicke’s area

Can you identify the role each structure plays in language production and comprehension?

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The Hemispheres: The Role of the Right

RESEARCH: RIGHT HEMISPHERE

More proficient in some visual tasks

Critical for understanding abstract and humorous use of language

Better for following conversations that change topics

Important for recognizing faces

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The Amazing Brain: Neuroplasticity

HUMAN STEM CELL

The brain undergoes constant alterations

Physical adaptation and repair—even after hemispherectomy

Growth of new connections and reorganization

Stem cells

Responsible for creating new neurons

Adult-born neurons exist

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The Cortex: A Peek Beneath the Skull (part 1)

THE CORTEX

Cerebral cortex

Processes information and surrounds nearly all of the brain structure

Meninges

Contains three thin layers that envelop and protect brain and spinal cord

See INFOGRAPHIC 2.4 for additional information.

Peel away the scalp and cut away the bony skull, and you will find still more layers of protection. Three thin membranes—the meninges—provide a barrier to both physical injury and infection. Bypass them, and the outermost layer of the brain, the cortex, is revealed.

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The Lobes: Specialized Areas of the Brain

Frontal lobe: higher-level cognitive functions like thinking, planning, and personality characteristics—located at the front and top of the brain.

Parietal lobe: integration of sensory information like touch and temperature—located at the top and back of the brain.

Occipital lobe: processing of visual formation—located at the back and center of the brain.

Temporal lobe: hearing and language comprehension—located at the center and front of the brain.

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The Lobes: Up Close and Personal (part 1)

Phineas Gage and the frontal lobes

In 1848, Gage was impaled by a 3-foot tamping rod through his cheek, brain, and skull that caused dramatic changes in his personality.

Modern scientists revisited these data and suggested that damage occurred in both hemispheres.

Fritsch and Hitzig and the motor cortex

By applying a mild shock to dogs’ cortexes, researchers demonstrated that the motor cortex region is involved in muscle movement.

Albert Einstein and the parietal lobes

A postmortem comparison of 35 male brain specimens and Einstein’s brain found that the region of Einstein’s parietal lobe responsible for visual spatial cognition and mathematical was thinking 15% larger than those of the control group.

Do you think Einstein had a superbrain?

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The Lobes: Up Close and Personal (part 2)

Penfield and the somatosensory cortex

Used method similar to Fritsch and Hitzig, showing which points along the motor cortex and somatosensory cortex corresponded to parts of the body

Developed model often represented by oversimplified “homunculus”

This illustration shows how areas on the motor and somatosensory cortex correspond to the various regions of the body. Parts of the body that are shown larger, such as the face and hands, indicate areas of greater motor control or sensitivity. The size of each body part reflects the amount of cortex allocated to it.

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The Lobes: Up Close and Personal (part 3)

Occipital lobes

Initial processing site for visual information in lower back of head

Primary visual cortex

Connects to optic nerve, where visual information is received and interpreted

Association areas

Integrates information from all over the brain

Located in all four lobes

See Table 2.2 for summary of region of the cortex.

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Social Media and Psychology

FACEBOOK IN THE BRAIN

Facebook friends range from zero to 5,000, averaging 338.

A preliminary study suggests friend volume may reflex something about a user’s brain.

There is a correlation between number of Facebook friends and density of gray matter in areas of the brain known for meaningful social movements (superior temporal sulcus) and facial recognition (entorhinal cortex).

So… are your Facebook friends a gray matter?

There is no shortage of data: “Each day, people send one billion posts to Facebook, tweet 400 million messages through Twitter, upload 12 years’ worth of videos to YouTube, and make 300,000 edits to Wikipedia” (Mesh, Tamir, & Heekeren, 2015, p. 771).

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Digging Below the Cortex (part 1)

DRAMA CENTRAL: THE LIMBIC SYSTEM

Fuels basic drives and processes emotions and memories

Hippocampus

Amygdala

Thalamus

Hypothalamus

The limbic system includes the hippocampus, amygdala, thalamus, and hypothalamus.

Hypothalamus: A small structure located below the thalamus that maintains a constant internal environment within a healthy range; helps regulate sleep–wake cycles, sexual

behavior, and appetite.

Amygdala: A pair of almond-shaped structures in the limbic system that processes aggression and basic emotions such as fear, as well as associated memories.

Thalamus: A structure in the limbic system that processes and relays sensory information to the appropriate areas of the cortex.

Hippocampus: A pair of structures located in the limbic system; primarily responsible for creating new memories.

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From the Pages of SCIENTIFIC AMERICAN

RESEARCH SUGGESTS SUGAR MAY HARM BRAIN HEALTH

Eating a lot of sugar or other carbohydrates can be hazardous to both brain structure and function.

Diabetes: Links to elevated risk of dementia and smaller hippocampus

High levels of glucose: Associated with worse memory, smaller hippocampus, and compromised hippocampal structure

CONCLUSION

Even in the absence of diabetes or glucose intolerance, high blood sugar may harm the brain and disrupt memory function.

Future research needed

And Now the Good News: Food for Thought?

DO YOU KNOW THE POTENTIAL BENEFITS FOR THE FOLLOWING FOODS?

Walnuts

Berries

Cocoa

Oily fish

Broccoli

See Table 2.3 for answer to the question.

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Digging Below the Cortex (part 2)

COMPONENTS OF THE BRAINSTEM

Brainstem

Includes the brain’s core

Extends from spinal cord to forebrain

Forebrain

Involves largest part of the brain and includes cerebral cortex and limbic system

Midbrain

Involves brainstem part involved in arousal levels, responsible for generating movement patterns in response to sensory input

Located beneath the structures of the limbic system, the brainstem includes the midbrain, pons, and medulla. These structures are involved in arousal, movement, and life-sustaining processes. The cerebellum is important for muscle coordination and balance and, when paired with the pons and medulla, makes up the hindbrain. Photo: Onoky/Corbis.

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Digging Below the Cortex (part 3)

COMPONENTS OF THE BRAINSTEM

Reticular formation

Involves network of neurons running through the midbrain

Controls levels of arousal and quickly analyzes sensory information on its way to the cortex

Hindbrain

Pons

Medulla

Cerebellum

Involves muscle coordination and balance

May also affect fine distinctions in cognition

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And Now?

LIFE IS GOOD

Three years after his traumatic brain injury, Brandon celebrated his marriage to Laura. The couple now has three children.

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