RESOURCES2A.docx

EVIDENCE-BASED PRACTICE IN NURSING

Before describing procedures relating to EBP in nursing, we briefly

discuss some important issues, including the nature of “evidence” and

challenges to pursuing EBP, and resources available to address some of

those challenges.

Types of Evidence and Evidence Hierarchies

There is no consensus about the definition of evidence nor about what

constitutes usable evidence for EBP, but most commentators agree that

findings from rigorous research are paramount. Debate continues,

however, about what constitutes rigorous research and what qualifies as

best evidence.

At the outset of the EBP movement, there was a strong bias toward

reliance on information from studies called randomized controlled trials

(RCTs). This bias stemmed from the fact that the Cochrane Collaboration

initially focused on the effectiveness of therapies rather on other types of

health care questions. RCTs are, in fact, very well suited for drawing

conclusions about the effects of health care interventions (Chapter 9). The

bias in ranking sources of evidence in terms of questions about effective

treatments led to some resistance to EBP by nurses who felt that evidence

from qualitative and non-RCT studies would be ignored.

Positions about the contribution of various types of evidence are less

rigid than previously. Nevertheless, many published evidence hierarchies

rank evidence sources according to the strength of the evidence they

provide, and in most cases, RCTs are near the top of these hierarchies. We

offer a modified evidence hierarchy that looks similar to others, but ours

illustrates that the ranking of evidence-producing strategies depends on the

type of question being asked.

Figure 2.1 shows that systematic reviews are at the pinnacle of the

hierarchy (Level I), regardless of the type of question, because the

strongest evidence comes from careful syntheses of multiple studies. The

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next highest level (Level II) depends on the nature of inquiry. For Therapy

questions regarding the efficacy of an intervention (What works best for

improving health outcomes?), individual RCTs constitute Level II

evidence (systematic reviews of multiple RCTs are Level I). Going down

the “rungs” of the evidence hierarchy for Therapy questions results in less

reliable evidence—for example, Level III evidence comes from a type of

study called quasi-experimental. In-depth qualitative studies are near the

bottom, in terms of evidence regarding intervention effectiveness. (Terms

in Figure 2.1 will be discussed in later chapters.)

For a Prognosis question, by contrast, Level II evidence comes from a

single prospective cohort study, and Level III is from a type of study called

case control (Level I evidence is from a systematic review of cohort

studies). Thus, contrary to what is often implied in discussions of evidence

hierarchies, there really are multiple hierarchies. If one is interested in best

evidence for questions about Meaning, an RCT would be a poor source of

evidence, for example. We have tried to portray the notion of multiple

hierarchies in Figure 2.1, with information on the right indicating the type

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of individual study that would offer the best evidence (Level II) for

different questions. In all cases, appropriate systematic reviews are at the

pinnacle. Information about different hierarchies for different types of

cause-probing questions is addressed in Chapter 9.

Of course, within any level in an evidence hierarchy, evidence quality

can vary considerably. For example, an individual RCT could be well

designed, yielding strong Level II evidence for Therapy questions, or it

could be so flawed that the evidence would be weak.

Thus, in nursing, best evidence refers to research findings that are

methodologically appropriate, rigorous, and clinically relevant for

answering persistent questions—questions not only about the efficacy,

safety, and cost-effectiveness of nursing interventions but also about the

reliability of nursing assessment tests, the causes and consequences of

health problems, and the meaning and nature of patients’ experiences.

Confidence in the evidence is enhanced when the research methods are

compelling, when there have been multiple confirmatory studies, and

when the evidence has been carefully evaluated and synthesized.

Of course, there continue to be clinical practice questions for which

there is relatively little research evidence. In such situations, nursing

practice must rely on other sources—for example, pathophysiologic data,

chart review, quality improvement data, and clinical expertise. As Sackett

and colleagues (2000) have noted, one benefit of the EBP movement is

that a new research agenda can emerge when clinical questions arise for

which there is no satisfactory evidence.

Evidence-Based Practice Challenges

Nurses have completed many studies about the use of research in practice,

including research on barriers to EBP. Studies on EBP barriers, conducted

in several countries, have yielded similar results about constraints on

clinical nurses. Most barriers fall into one of three categories: (1) quality

and nature of the research, (2) characteristics of nurses, and (3)

organizational factors.

With regard to the research, one problem is the limited availability of

high-quality research evidence for some practice areas. There remains an

ongoing need for research that directly addresses pressing clinical

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problems, for replication of studies in a range of settings, and for greater

collaboration between researchers and clinicians. Another issue is that

nurse researchers need to improve their ability to communicate evidence,

and the clinical implications of evidence, to practicing nurses.

Nurses’ attitudes and education are also potential barriers to EBP.

Studies have found that some nurses do not value or know much about

research, and others simply resist change. Fortunately, many nurses do

value research and want to be involved in research-related activities.

Nevertheless, many nurses do not know how to access research evidence

and do not possess the skills to critically evaluate research findings—and

even those who do may not know how to effectively incorporate research

evidence into clinical decision making. Among nurses in non-Englishspeaking

countries, another impediment is that most research evidence is

reported in English.

Finally, many of the challenges to using research in practice are

organizational. “Unit culture” can undermine research use, and

administrative and other organizational barriers also play a major role.

Although many organizations support the idea of EBP in theory, they do

not always provide the necessary supports in terms of staff release time

and availability of resources. Nurses’ time constraints are a crucial

deterrent to the use of evidence at the bedside. Strong leadership in health

care organizations is essential to making evidence-based practice happen.

RESOURCES FOR EVIDENCE