Write an essay on targeting Epidermal growth factor receptor (EGFR) with tyrosine kinase inhibitors or TKIs to treat Patients with Lung cancer and the role of mutations developing resistance and sensitization
Reading Materials
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Zhenfang Du and Christine M. Lovly. Mechanisms of receptor tyrosine kinase activation in cancer. Molecular Cancer (2018) 17:58 https://doi.org/10.1186/s12943-018-0782-4
Marta Román, Iosune Baraibar, Inés López, Ernest Nadal, Christian Rolfo, Silvestre Vicent and Ignacio Gil-Bazo. KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target. Molecular Cancer (2018) 17:33 https://doi.org/10.1186/s12943-018-0789-x
Ammad Ahmad Farooqia, Marc de la Rocheb, Mustafa B.A. Djamgozc,d, Zahid H. Siddike. Overview of the oncogenic signaling pathways in colorectal cancer: Mechanistic insights. Seminars in Cancer Biology, Volume 58, October 2019, Pages 65-79. https://doi.org/10.1016/j.semcancer.2019.01.001