HW DUE IN 1 hour 20 min. questions and answers

Molecular & Genomic Epidemiology Assignment 4 Due: 11-12-2019

Q1: Review the study titled “Molecular Epidemiology of HIV Transmission in a Dental

Practice”.

A. Describe the design of the study

B. Explain the findings of the study as presented in table 1.

C. Describe the phylogenetic tree as presented in figure 1.

D. Do you agree with the conclusion of the study that “these five patients were infected during

their dental care.”? Justify your answer.

Q2: Review the study titled “Lack of HIV Transmission in the Practice of a Dentist with AIDS”.

A. Describe the design of the study

B. Explain the findings of the study as presented in tables 1 and 2.

C. Describe the phylogenetic tree as presented in figure 1.

D. Do you agree with the conclusion of the study that “no evidence of patient-to-patient

transmission of HIV within this dental practice”? Justify your answer.

Q3: Consider the study “Vector Competence of American Mosquitoes for Three Strains of Zika

Virus”.

A. Provide a brief summary of the study.

B. Explain the finding of the study as presented in Figure 1.

C. Use the sequences in the file zika and CLUSTALW to generate rooted & un-rooted trees.

D. Compare and contrast your rooted tree to the tree presented in the Figure 1.

Q4: Review the study titled “Bacillus cereus efflux protein BC3310–amultidrug transporter of

the unknown major facilitator family, UMF-2”

A. Provide a brief summary of the study.

B. Explain the finding of the study as presented in Figure 1.

C. Use the sequences in the file bac1 and CLUSTALW to generate a phylogenetic tree.

D. Compare and contrast your tree to the tree presented in in Figure 1.

Q5: Provide an update on the progress of your project.