Problem set 2

CHE 4427-01 Biochemistry II SPRING 2021

Problem Set #2

Answer the following questions

1. Why protein degradation needs ATP even though proteolysis is an exergonic reaction?

2. What are the true glucogenic and true ketogenic amino acids from out of 20 standard amino acids?

3. Which amino acid produces melatonin and what modifications occur for its formation?

4. Explain why it is advantageous for humans to adapt to high altitude increase in GLUT1 and phosphofrutokinase in muscle?

5. Which are the two reactions that allow the kidney to produce NH4+ ?

6. Why adipose tissue can be considered as an endocrine organ?

7. Why insulin is required for adipose cells to synthesize TAG from FA?

8. What are the consequences if there is an overdose of insulin on human brain function in a normal healthy person?

9. Explain the reason for insulin injection for Type I diabetes, while on the contrary, Type II diabetes does require insulin injections only partially.

10. From which purine caffeine is derived and explain with reaction?