Brochure creation

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pharmwk8OAB.docx

Facts

· Effects people of all genders, race, and socioeconomic background

· Official reports state between 16-17% of adults suffer from OAB, but this number is likely higher due to underreporting and challenges to diagnose. (Arcangelo, et.al., 2022)

· Risk increases with age

· Exact cause is multi-factorial

· Differential diagnosis includes: bladder cancer, interstitial cystitis, endometriosis, prostate cancer, bacterial cystitis, urinary retention, etc. (Arcangelo, et.al, 2022)

Medications

· Oxybutynin (Ditropan)

· Mirabegron (Myrbetriq)

· Duloxetine (Cymbalta)

Treatment

· Transcutaneous tibial nerve stimulation has shown to be a potential treatment, is self-managed (Daly, et.al, 2021)

· Anticholinergic medications are a common route of treatment

· Injection of Botox is also an effective treatment for OAB (Hoover, et.al, 2022)

· Bladder training, promotion of exercise and diet changes are least invasive and should be tried first

Overactive Bladder

A condition involving urinary urgency, frequency, and nocturia; with or without incontinence.

Kerry Monahan

NSG 5510 Advanced Pharmacology

Ron and Kathy Assaf School of Nursing, Nova Southeastern University

Dr. McGhie

10/16/2022

References:

Arcangelo, V.P., Peterson, A. W., Wilbur, V., & Reinhold, J.A. (2022). Pharmacotherapeutics for advanced practice: A practical approach. (5th Ed.) Wolters Kluwer.

Daly, C. M. E., Loi, L., Booth, J., Saidan, D., Guerrero, K., & Tyagi, V. (2021). Self-management of overactive bladder at home using transcutaneous tibial nerve stimulation: a qualitative study of women’s experiences.  BMC Women’s Health21(1), 1–9. https://www-doi-org.ezproxylocal.library.nova.edu/10.1089/gyn.2021.0036

Hoover, M. L., Karram, M. M., Farley, G., & Shah, A. (2022). Subjective efficacy of suburothelial versus intradetrusor botulinum toxin for overactive bladder: a retrospective cohort study.  Journal of Gynecologic Surgery38(2), 103–106. https://doi-org.ezproxylocal.library.nova.edu/10.1089/gyn.2021.0036

Minassian, V. A., Devore, E., Hagan, K., & Grodstein, F. (2013). Severity of urinary incontinence and effect on quality of life in women by incontinence type. Obstetrics & Gynecology, 121(5), 1083–1090.  https://doi.org/10.1097/aog.0b013e31828ca761

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