GI Histology Lab

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PAL3_Histology_Digestive_System_Atlas-1.pptx

Esophagus, Lower Third; Cross Section 40x

Submucosa

Stratified squamous epithelium

Mucosa

Adventitia

Longitudinal muscle of muscularis externa

Circular muscle of muscularis externa

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A cross sectional micrograph highlights the features of the lower third esophagus, magnified forty times. From top to bottom, they are as follows. Circular muscle of muscularis externa, submucosa, stratified squamous epithelium, longitudinal muscle of muscularis externa, mucosa, and adventitia.

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Esophagus, Lower Third; Cross Section 100x

Submucosa

Muscularis mucosae

Lamina propria

Stratified squamous epithelium

Circular muscle of muscularis externa

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A cross sectional micrograph highlights the features of the lower third esophagus, magnified one hundred times. From top to bottom, they are as follows. Circular muscle of muscularis externa, submucosa, muscularis mucosae, lamina propria, and stratified squamous epithelium.

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Esophagus, Lower Third, Mucosa; Cross Section 400x

Stratified squamous epithelium

Muscularis mucosae

Lamina propria

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Esophagus; Cross Section 40x

Submucosa

Adventitia

Muscularis externa

Lamina propria

Lumen

Stratified squamous epithelium

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Esophagus; Cross Section 100x

Stratified squamous epithelium

Submucosa

Circular muscle of muscularis externa

Lamina propria

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Esophagus, Mucosa; Cross Section 200x

Muscularis mucosae

Lamina propria

Stratified squamous epithelium

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Fundic Stomach; Cross Section 40x

Serosa

Longitudinal muscle of muscularis externa

Circular muscle of muscularis externa

Oblique muscle of muscularis externa

Submucosa

Mucosa

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A cross sectional micrograph highlights the features of a fundic stomach, magnified forty times. From top to bottom, they are as follows. Mucosa, submucosa, oblique muscle of muscularis externa, serosa, circular muscle of muscularis externa, and longitudinal muscle of muscularis externa.

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Fundic Stomach; Cross Section 100x

Simple columnar epthelium

Gastric pits

Parietal cells

Chief cells

Muscularis mucosae

Oblique muscle of muscularis externa

Submucosa

Gastric glands in lamina propria

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A cross sectional micrograph highlights the features of a fundic stomach, magnified one hundred times. From top to bottom, they are as follows. Gastric glands in lamina propria, simple columnar epithelium, gastric pits. Submucosa, parietal cells, chief cells, oblique muscle of muscularis externa, and muscularis mucosae.

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Fundic Stomach; Cross Section 400x

Simple columnar epthelium

Gastric pits

Parietal cells

Gastric glands in lamina propria

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Stomach, Layers Of The Gastric Wall; Cross Section 20x

Serosa

Muscularis externa

Submucosa

Mucosa

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Stomach; Cross Section 100x

Parietal cells

Gastric pits

Gastric glands in lamina propria

Muscularis mucosae

Submucosa

Arteriole

Venule

Chief cells

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A cross sectional micrograph highlights the features of a stomach, magnified one hundred times. From top to bottom, they are as follows. Gastric pits, venule, chief cells, parietal cells, arteriole, submucosa, muscularis mucosae, and gastric glands in lamina propria.

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Simple Columnar Epithelium, Small Intestine; Cross Section 1000x

Goblet cell

Simple columnar epithelium

Basement membrane

Nuclei

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Duodenum, Plica Circulares; Cross Section 40x

Villi

Intestinal crypts

Submucosa of plica circulares

Muscularis externa

Duodenal glands

Mucosa of plica circulares

Plica circulares

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A cross sectional micrograph highlights the features of a duodenum plica circulares, magnified forty times. From top to bottom, they are as follows. Plica circulares, mucosa of plica circulares, villi, submucosa of plica circulares, duodenal glands, intestinal crypts, and muscularis externa.

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Duodenum; Cross Section 40x (1 of 2)

Villus

Submucosa of plica circulares

Serosa

Duodenal glands

Muscularis externa

Mucosa of plica circulares

Plica circulares

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A cross sectional micrograph highlights the features of a duodenum, magnified forty times. From top to bottom, they are as follows. Plica circulares, villus, mucosa of plica circulares, muscularis externa, submucosa of plica circulares, duodenal glands, and serosa.

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Duodenum; Cross Section 100x

Simple columnar epithelium

Villi

Duodenal glands

Longitudinal muscle of muscularis externa

Circular muscle of muscularis externa

Intestinal crypts

Muscularis mucosae

Submucosa

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A cross sectional micrograph highlights the features of a duodenum, magnified one hundred times. From top to bottom, they are as follows. Submucosa, simple columnar epithelium, villi, muscularis mucosae, intestinal crypts, circular muscle of muscularis externa, duodenal glands, and longitudinal muscle of muscularis externa.

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Duodenum; Cross Section 400x

Nuclei

Lamina propria of villus

Villus

Microvilli

Simple columnar epithelium

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A cross sectional micrograph highlights the features of a duodenum, magnified four hundred times. From top to bottom, they are as follows. Nuclei, simple columnar epithelium, microvilli, lamina propria of villus, and villus.

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Duodenum, Muscularis Externa; Cross Section 400x (1 of 2)

Circular muscle

Myenteric nerve plexus

Serosa

Longitudinal muscle

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A cross sectional micrograph highlights the features of a duodenum muscularis externa, magnified four hundred times. From top to bottom, they are as follows. Longitudinal muscle, circular muscle, serosa, and myenteric nerve plexus.

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Duodenum; Cross Section 40x (2 of 2)

Villi

Mucosa

Submucosa

Muscularis externa

Serosa

Duodenal glands

Intestinal crypts

Muscularis mucosae

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A cross sectional micrograph highlights the features of a duodenum, magnified forty times. From top to bottom, they are as follows. Mucosa, villi, muscularis mucosae, submucosa, intestinal crypts, muscularis externa, duodenal glands, and serosa.

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Large Intestine; Longitudinal Section 40x

Submucosa

Serosa

Teniae coli

Circular muscle of muscularis externa

Mucosa

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Large Intestine; Longitudinal Section 100x

Intestinal crypts

Simple columnar epithelium

Circular muscle of muscularis externa

Submucosa

Muscularis mucosae

Goblet cells

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A longitudinal micrograph highlights the features of the large intestine, magnified one hundred times. From top to bottom, they are as follows. Intestinal crypts, goblet cells simple columnar epithelium, muscularis mucosae, submucosa, and circular muscle of muscularis externa.

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Large Intestine, Mucosa; Longitudinal Section 200x

Intestinal crypts

Simple columnar epithelium

Submucosa

Muscularis mucosae

Goblet cells

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A longitudinal micrograph highlights the features of a large intestine mucosa, magnified forty times. From top to bottom, they are as follows. Intestinal crypts, goblet cells, simple columnar epithelium, muscularis mucosae, and submucosa.

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Liver; Cross Section 40x (1 of 2)

Liver lobules

Portal triads

Central veins

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Liver; Cross Section 100x

Liver lobule

Central vein

Portal triads

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Liver; Cross Section 200x

Portal triad

Hepatic portal venule

Hepatic arteriole

Bile duct

Hepatocytes

Central vein

Sinusoids

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Liver; Cross Section 40x (2 of 2)

Liver lobule

Central vein

Liver sinusoids

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Liver, Portal Triad; Cross Section 400x (1 of 2)

Hepatic arteriole

Hepatic portal venule

Sinusoid

Hepatocytes

Bile duct

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Liver, Portal Triad; Cross Section 400x (2 of 2)

Bile duct

Hepatic arteriole

Hepatic portal venule

Hepatocytes

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Liver, Central Vein; Cross Section 1000x

Hepatocytes

Sinusoids

Central vein

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Gall Bladder Wall

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The gallbladder is the storage vessel for bile. Its wall is composed of the following layers:

Mucosa (or mucous membrane) - the empty bladder has numerous deep folds (or rugae) often resulting in the appearance of cross bridges.

Simple Columnar Epithelium - similar in appearance to absorptive cells in the intestines.

Lamina Propria - dense irregular connective tissue that supports the epithelium. It is rich in fenestrated capillaries and small venules.

Tunica Muscularis - randomly oriented bundles of smooth muscle containing numerous collagen and elastic fibers. Its contraction results in emptying of the gallbladder.

Outer Layer of Connective Tissue - composition depends on its location.

Adventitia - where the gallbladder attaches to the liver. It is composed of dense irregular connective tissue.

Serosa - where the gallbladder is unattached to the liver. It is composed of a surface layer of mesothelium supported by loose connective tissue.

Despite its origin from the foregut, the gallbladder does not have a muscularis mucosae or submucosa.

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Gall Bladder Wall

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Gall Bladder Mucosa

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