P4#1,P4#2

 

Anna Woody

Initial Post - Week 4

Initial Post

This week we have been asked to pick, review, and reflect on the ethical principles regarding a current health-related case involving

research ethics. The case I have chosen relates clinical trials in children. Clinical trials are important to advance pharmacology in

many pediatric diseases. "Medical research involving children is essential for advancing child health and well-being"

(Sammons & Starkey, 2016). Children are not small adults, and their reactions to medications vary in age and weight. In any research,

there are risks and benefits involved. "If the risks and benefits are not disclosed, then there is a breach of beneficence. In any study,

the researchers are mandated to minimize harm and actually limit participants from any harm" (Polit & Beck, 2017).

Potential child participants in clinical research trials in low-income countries are often vulnerable because of poverty, high morbidity

and mortality, inadequate education, and varied local cultural norms. (MacLeod, Knoppert, Jean, & Avard, 2015).

In order to participate in a clinical study, informed consent must be obtained. Children can not give consent until the age of 18 or

unless deemed competent by a judge. Therefore, the parent or parent(s) are making decisions that may cause harm to the child.

Obtaining informed consent continues to be a concern in all areas of medical research. It is an ongoing battle involving the court system

even today.

Research in children needs to be safe and ethical. Pediatric clinical trials have increased survival rate of many conditions.

Would you allow your child to be a part of a clinical trial? Luckily my children are grown and I was never faced with this type of decision to make.

References

MacLeod, S. M., Knoppert, D. C., Stanton-Jean, M., & Avard, D. ( 2015). Pediatric Clinical Drug Trials in low-income countries: Key ethical issues.

Retrieved from Walden University Library:

https://eds-b-ebscohost-com.ezp.waldenulibrary.org/eds/pdfviewer/pdfviewer?vid=8&sid=7d6997ed-a238-47c7-817f-108412a54110%40pdc-v-sessmgr02

Polit, D.F., & Beck, C.T. (2017). Nursing research: Generating and assessing evidence for nursing practice (10th ed.). Philadelphia, PA: Wolters Kluwer.

Sammons, H. & Starkey, E. (2016). Ethical issues of clinical trials in children. Retrieved from Walden University Library Database:

https://www-sciencedirect-com.ezp.waldenulibrary.org/science/article/pii/S1751722215001973?via%3Dihub

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