proposal

Name: MANEAF AFET ALRAWAILI

ID:421103847

Evaluation of Serum Insulin Level as a Marker of

Insulin Resistance in Obese with and without

Diabetes Type-2

AIM AND OBJECTIVES:

Aim :

Measure level of serum insulin for identification of insulin resistance in obese persons

with or without diabetes in comparison to non-obese non-diabetic controls.

Objectives:

• To measure fasting serum Insulin Level, FBG in obese persons with or without

Diabetes in comparison to no obese non-diabetic control group.

• To find out correlation between BMI and fasting Serum Insulin level in all these

groups.

Methods:

All the subjects are divided into 3 groups selected on the basis of BMI: -

*Group I Consisted of 150 obese persons (BMI>25) freshly diagnosed as Type-2

diabetes mellitus confirmed by clinical and laboratory investigations.

*Group II Consisted of 150 obese persons (BMI>25) without Type-2 DM.

Group III Consisted of 150 non obese non diabetic healthy persons (BMI<25). *

- Estimate and collecting tests result from laboratory for serum glucose and Serum

Insulin.

Outcome:

Find significant to estimate the status of insulin resistance (by measuring serum insulin

level) in this population group so that effective preventive measures can be initiated at

very early stage. This study will help us in future to guide more and more patients and

their physicians to correlate between obesity and diabetes.