Build a Budget Impact Analysis Model

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No3.pptx

HCDA 515: example summary deck

Weekend # 1: team presentation and individual assignment example

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Budget Impact of product “X” in Patients with Disease “Y”

Team Name or Individual Name

Case study Number

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The objective and research question

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For a health plan of 1M members, the model estimates the budget impact in each year over a five-year period that would result from the introduction of Product “X” as a treatment option for patients with Disease “Y”

Two scenarios are compared:

Assumes treatment of patients with disease “Y” without Product “X” as a treatment option

WORLD WITHOUT PRODUCT X

WORLD WITH PRODUCT X

Assumes treatment of patients with disease “Y” with Product “X” as a treatment option

Budgetary impact is calculated as the difference in costs between the two scenarios

1M: One Million

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Model overview

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1 to 5 year(s) with 3 years as base case

Commercial: Patients with Disease “Y”

Medicare Advantage: Patients 65+ with Disease “Y”

Third-party payer in the US

Comparator A (Brand)

Comparator B (Brand)

Comparator C (Brand)

Comparator D (Generic)

Comparator E (Generic)

Comparator F (Generic)

Comparator G (Generic)

Comparator H (Generic)

To estimate the budget impact of Product “X” for Disease “Y”

OBJECTIVE

TIME HORIZON

PERSPECTIVE

POPULATION

COMPARATORS

Drug acquisition costs (2019 US Dollars)

Drug administration costs (2019 US Dollars)

COST INPUTS

Total scenario costs

Total cost per member per month (PMPM)

OUTPUTS

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Model flow

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Patients with Disease “Y” and failing 1st Line

ELIGIBLE POPULATION

Therapies without Product “X”

Therapies with Product “X”

TREATMENT MIX

Drug acquisition

Drug administration

Treatment Duration

TREATMENT COSTS

$

Total scenario costs

Total PMPM

MODEL RESULTS

Hypothetical plan of 1,000,000 members

TOTAL POPULATION

Patients with Disease “Y”

DISEASE

PATIENT POPULATION

DISEASE TREATMENTS

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Epidemiology inputs

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Input Commercial Medicare Advantage
Value Details Value Details
Disease “Y” 50.80% Source and methods to utilize 55% Source and methods to utilize
Failed 1st Line 23.81% Source and methods to utilize 100% Source and methods to utilize
Treated after 1st Line 1.65% Source and methods to utilize 4.60% Source and methods to utilize
With Recent Event 54% Source and methods to utilize 54% Source and methods to utilize

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Treatment mix inputs

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Year 1 Year 2 Year 3 Year 4 Year 5
Product “X” 0.0% 0.0% 0.0% 0.0% 0.0%
Comparator A 43.9% 43.9% 43.9% 43.9% 43.9%
Comparator B 3.0% 3.0% 3.0% 3.0% 3.0%
Comparator C 6.1% 6.1% 6.1% 6.1% 6.1%
Comparator D 9.3% 9.3% 9.3% 9.3% 9.3%
Comparator E 7.5% 7.5% 7.5% 7.5% 7.5%
Comparator F 0.8% 0.8% 0.8% 0.8% 0.8%
Comparator G 29.2% 29.2% 29.2% 29.2% 29.2%
Comparator H 0.3% 0.3% 0.3% 0.3% 0.3%
Total 100% 100% 100% 100% 100%

Current Scenario (without EVENITY™)

Year 1 Year 2 Year 3 Year 4 Year 5
Product “X” 0.0% 0.2% 0.2% 0.4% 0.4%
Comparator A 43.9% 43.9% 43.9% 43.9% 43.9%
Comparator B 3.0% 3.0% 3.0% 3.0% 3.0%
Comparator C 6.1% 6.1% 6.1% 6.1% 6.1%
Comparator D 9.3% 9.3% 9.3% 9.3% 9.3%
Comparator E 7.5% 7.5% 7.5% 7.5% 7.5%
Comparator F 0.8% 0.7% 0.7% 0.6% 0.6%
Comparator G 29.2% 29.2% 29.1% 29.1% 29.1%
Comparator H 0.3% 0.2% 0.2% 0.2% 0.2%
Total 100% 100% 100% 100% 100%

Current Scenario (with EVENITY™)

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Cost Inputs: Drug Acquisition and Administration

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Drug Brand/Generic Dose Frequency Strength Doses per Administration / Year WAC Annual Cost
Product “X” Brand Monthly 210 mg 2 / 12 $22,173
Comparator A Brand Weekly 70 mg 1 / 52 $98
Comparator B Brand Daily 5 mg 1 / 365 $2,586
Comparator C Brand Monthly 150 mg 1 / 12 $340
Comparator D Generic Annually 5 mg 1 / 1 $300
Comparator E Generic Daily 60 mg 1 / 365 $1,341
Comparator F Generic Daily 20 mcg 1 / 365 $40,086
Comparator G Generic Biannually 60 mg 1 / 2 $2,438
Comparator H Generic Daily 80 mg 1 / 365 $22,173

Drug Acquisition Costs

Administration and Services Fees

Commercial Medicare Advantage
Subcutaneous Injection $21.72 $16.94
One IV Infusion $93.33 $72.80

Provide sources and methods

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Patient population – Commercial Perspective shown

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Provide sources and methods

Provide sources and methods

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Results: per member per month for commercial

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Over 5 years, the budget impact of Product “X” is estimated to be -$0.001 PMPM in a hypothetical 1M commercial member plan

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PMPM

Year 1 Year 2 Year 3 Year 4 Year 5 Net (Years 1 - 5) 0 -1E-3 -1E-3 -2E-3 -2E-3 -1E-3

Results: cumulative budget impact for commercial

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Under the new scenario, cumulative costs are reduced by an estimated $75,566 over 5 years across 1M commercial members

Projected Total Costs Between Scenarios Over 5 Years

Net Difference

-$75,566

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Current Scenario New Scenario 6925739 6850172

Assumptions and Limitations

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The model assumes all patients complete the entire treatment duration

The model assumes the eligible population identified reflects the size of the population that may be eligible for Product “X”

The treatments included are assumed to reflect the treatments utilized among the eligible population

Treatment costs are assumed to be similar to the wholesale acquisition cost (WAC)

Assumptions

The model is focused on drug acquisition and drug administration costs only and does not consider differences in efficacy that may impact initial treatment

The model excludes the cost of other treatment-related resources including therapeutic drug monitoring, hospital costs, laboratory and diagnostic tests and any procedures or additional medications

Limitations

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Conclusions

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-$1,033,609

Budget Impact

Total Cumulative

-$0.017

decrease

Per Member Per Month

1M: One Million

The entry of Product “X” for Disease “Y” introduces the question of affordability for health plans.

The budget impact model demonstrates cost savings in a hypothetical 1M member health plan in both the Commercial and Medicare Advantage settings

The results should be interpreted within the context of the data inputs and modeling assumptions used as the results may be sensitive to changes in these inputs

-$75,566

Budget Impact

Total Cumulative

-$0.001

decrease

Per Member Per Month

Commercial

Medicare Advantage

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