Discussion/ Effect of Cholesterol in the Human Body


Effect of Cholesterol in the Human Body 

Hook: As per the Centers for Disease Control and Prevention (CDC) About 38% of American grown-ups have elevated cholesterol (complete blood cholesterol ≥ 200 mg/dL). 

Background Information: Cholesterol comes from two sources; the liver, and the rest come from foods like meat and dairy. The human body needs cholesterol to function; however, elevated levels of cholesterol can cause cardiovascular problems. “There are two types of cholesterol, based on what the lipoprotein carries. They are low-density lipoprotein (LDL) known as “bad” cholesterol, and high-density lipoprotein (HDL) known as “good" cholesterol.” 

Problem Statement: Elevated cholesterol can cause a cardiovascular problem. 

Research problem: As the measure of cholesterol in the blood increments, so does the danger to the person’s wellbeing. 

Hypothesis: An approach may be having a good diet and stay active; this could help the person to control the cholesterol. 

Thesis Statement: The purpose of this paper is to educate people that elevate cholesterol can put their lives in risk.


Centers for Disease Control and Prevention. (2020, January 31). LDL & HDL: Good & Bad Cholesterol. Centers for Disease Control and Prevention. 


The table below breaks down the main topics that were addressed in each article and their relationship to the topic to be investigated. The chosen criteria were Criterion 1 The risk of cardiovascular disease due to the cholesterol levels. Criterion 2 Benefits of exercises & healthy food Criterion 3 use of medications to lower cholesterol.


Effect of Cholesterol in the Human Body 


Criterion 1: Risk for cardiovascular diseases 

Criterion 2: Benefits of exercises & healthy food

Criterion 3: use of medications to lower cholesterol

Jeong et al. (2018)



Soran et al.(2018)

 Partially influencing  

Partially influencing

Impacting in patient with High Cholesterol levels

Estruch et al. (2018)




Sonoda et al.(2018)




Wahid et al.(2016)




Effect of Cholesterol in the Human Body


Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M. I., Corella, D., Arós, F., ... & Martínez-González, M. A. (2018). Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. New England journal of medicine378(25), e34. 

Jeong, S. M., Choi, S., Kim, K., Kim, S. M., Lee, G., Park, S. Y., ... & Park, S. M. (2018). Effect of change in total cholesterol levels on cardiovascular disease among young adults. Journal of the American Heart Association7(12), e008819. 

Sonoda, T., Takumi, T., Miyata, M., Kanda, D., Kosedo, I., Yoshino, S., & Ohishi, M. (2018). Validity of a novel method for estimating low-density lipoprotein cholesterol levels in cardiovascular disease patients treated with statins. Journal of atherosclerosis and thrombosis, 44396. 

Soran, H., Adam, S., & Durrington, P. N. (2018). Optimizing treatment of hyperlipidemia: Quantitative evaluation of UK, USA and European guidelines taking account of both LDL cholesterol levels and cardiovascular disease risk. Atherosclerosis278, 135-142. 

Wahid, A., Manek, N., Nichols, M., Kelly, P., Foster, C., Webster, P., ... & Scarborough, P. (2016). Quantifying the association between physical activity and cardiovascular disease and diabetes: a systematic review and meta‐analysis. Journal of the American Heart Association5(9), e002495