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Full citation of selected article

Article #1

Article #2

Article #3

Article #4

Azzoli, C. G., Temin, S., & Giaccone, G. (January 01, 2012). 2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer. Journal of Oncology Practice, 8, 1, 63-6.

Lindeman, N. I., Cagle, P. T., Beasley, M. B., Chitale, D. A., Dacic, S., Giaccone, G., Jenkins, R. B.... College,. A. P. I. A. S. L. C. A. M. P. (January 01, 2013). Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. The Journal of Molecular Diagnostics: Jmd, 15, 4, 415-53.

Rodrigues, G., Videtic, G. M., Sur, R., Bezjak, A., Bradley, J., Hahn, C. A., Langer, C.... Movsas, B. (January 01, 2011). Palliative thoracic radiotherapy in lung cancer: An American Society for Radiation Oncology evidence-based clinical practice guideline. Practical Radiation Oncology, 1, 2.)

Lim, E., Baldwin, D., Beckles, M., Duffy, J., Entwisle, J., Faivre-Finn, C., Kerr, K.... Win, T. (October 01, 2010). Guidelines on the radical management of patients with lung cancer. Thorax, 65.

Why you chose this article and/or how it relates to the clinical issue of interest (include a brief explanation of the ethics of research related to your clinical issue of interest)

The choice for this article is premised on the fact that it is relevant to the project’s subject matter and fulfils the requirement of the project’s instructions. It presents one of the sets of clinical practice guidelines for lung cancer. The guidelines are for the American Society of Clinical Oncology. The article is valid also because it is empirical and peer-reviewed according to ethics of research.

This article is selected because it is relevant to both the topic under study and the instruction requirements. It avails molecular testing guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors.

Relevancy, and hence appropriateness is also the reason behind the selection of this resource. The project seeks to identify and assess lung cancer clinical guidelines. This article presents another set of these guidelines, specifically under palliative thoracic radiotherapy.

This is another article whose content is necessary in addressing the subject matter of this project. The report presents another set of clinical guidelines in the management of lung cancer. As such, its selection is based on its suitability and applicability to the project in hand.

Brief description of the aims of the research of each peer-reviewed article

The main aim of this article was to update one recommendation of the ASCO Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer (NSCLC) regarding switch maintenance chemotherapy by ASCO.

The main purpose of this study was to establish evidence-based recommendations for the molecular analysis of lung cancers necessary in guiding EGFR- and ALK-directed therapies, addressing the patient and samples’ types, which should be tested, including when and how the testing ought to be done.

The article’s key purpose providing physicians and patients’ guidance with regard to the use of external beam radiotherapy, endobronchial brachytherapy, and concurrent chemotherapy in the setting of palliative thoracic treatment for lung cancer, based on available evidence complemented by expert opinion.

The main purpose of the study was to establish appropriate guidelines on the radical management of patients with lung cancer.

Brief description of the research methodology used Be sure to identify if the methodology used was qualitative , quantitative , or a mixed-methods approach. Be specific.

The study employed literature review as a research methodology. However, it reviewed only literature from quantitative studies such as form phase III clinical trials and randomized controlled trials of carboxyaminoimidazole. This gives the research a quantitative study design.

Like the first article, this one also employs literature review as a study methodology. However, its design is also quantitative because the reviewed literature are of quantitative studies. About 1533 articles’ abstracts were searched and screened to identify 521 pertinent articles, which were reviewed.

The study executed system review as a research methodology. An American Society for Radiation Oncology (ASTRO) Board of Director’s certified Task Force synthesized and assessed evidence from 3 systematic reviews on the following topics: (1) dose fractionation in thoracic external beam radiotherapy (EBRT); (2) clinical utility of initial and salvage endobronchial brachytherapy (EBB); and (3) use of concurrent chemotherapy (CC) with palliative thoracic radiotherapy. Practice guideline recommendations were produced.

Quantitative analysis was adopted as the methodology of the study. Jointly, the British Thoracic Society and the Society for Cardiothoracic Surgery in Great Britain and Ireland undertook an initiative to update the 2001 guidelines for the selection and assessment of patients with lung cancer who can potentially be managed by radical treatment.

A brief description of the strengths of each of the research methodologies used, including reliability and validity of how the methodology was applied in each of the peer-reviewed articles you selected.

The strengths of the article’s methodology is that its study design allows for greater objectivity and accuracy of results. Credibility of studies starts with them being objective and yielding accurate results. The design was applied by searching and analyzing empirical literature about the study’s topic. The methodology is reliable and credible.

Quantitative studies allows for greater objectivity and results’ accuracy. The literature review was implemented by conducting three unbiased literature searches of electronic database. Quantitative study design are highly reliable because of their empirical natures.

The greatest strength of this study is that it is empirical given that it is based on available evidence. Another factor is that the systematic review was complemented by expert opinion. All these works contributes to the best interest of the credibility of the study. Unfortunately, the research is based on a limited number of system reviews (3).

One of the major strengths of this study is that it was quantitative in nature. All the practices undertaken in updating of these guidelines were empirical. Thus, the study was objective. However, its scope of evidence was limited only utilizing a few references.

General Notes/Comments

The article is credible and relevant to this project

The article is credible and relevant to this project.

The article is credible and relevant to this project.

The article is credible and relevant to this project.