Minamata Disease

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Minamata Disease

Chronic Disease & Country Information: 2-4 slides

Chisso Factory, Japan (Takizawa, 1979).

Primary: Minamata Bay, Kumamoto Prefecture

Secondary: Agano River Basin, Niigata Prefecture (Takizawa, 1979).

The Dancing Cat Disease vs. The Mad Hatter Disease (O'Carroll et al., 1995).

Figure 1

Areas with outbreak of Minamata disease

Note. From Areas with outbreak of Minamata disease by Environmental Health Department, Environment Agency, 1999, Minamata Disease Archives ( http://nimd.env.go.jp/archives/english/minamata_disease_in_depth/). In the Public Domain.

Minamata Disease describes the most severe type of mercury poisoning that targets the central nervous system (Eto et al., 2010), thereby disrupting the brain, causing severe dysfunction and even death (Jackson, 2018). This noninfectious disease was caused by industrial pollution known as effluent from a nearby manufacturing plant called the Chisso factory. It had been producing acetaldehyde since 1932, but production ramped up to help combat the trade deficit that occurred as a result on World War II. When

Minamata Disease took place in Japan between 

caused by industrial pollution known as effluent that originated from the Chisso Factory

Sushi

primarily imapacted residents of Minamata bay in Kumamoto prefecture Japan starting in the 1950s. It also secondarily impacted citizens near Niigata bay 

Because Minamata disease occurred as a result of industrial pollution,

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Chronic Disease & Country Information: 2-4 slides

Risk factors

Bioaccumulation & Biomagnification

Fishing community

Incidence

Prevalence

Mortality

Figure 2

Pathway of Methylmercury from Factory to Human

Note. From Pathway of Methylmercury from Factory to Human, n.d., Minamata Disease Archives ( http://nimd.env.go.jp/archives/english/minamata_disease_in_depth/). In the Public Domain.

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Chronic Disease & Country Information: 2-4 slides

Demographics:

Industrial workers, local community members, and fishermen were the most impacted people. 

Those who live in homes around the plant, the Minamata Bay, or the Agano river basin were the most affected populations (Torrente, 2019). 

Figure 3.  Minamata Disease Relief locations, Adapted From, "Minamata disease is caused by methylmercury poisoning. The name comes from Minamata Bay in Kumamoto prefecture where the Chisso factory released industrial waste. During 1932-1968 local residents, especially fisher families, suffered the consequences".  Torrente, D. (2019).  https://ejatlas.org/conflict/minamata-disease-japan 

When Minamata disease began to breakout in the 1950's, the country of Japan made an action plan to create relief for those who were affected by Minamata disease. The picture in the slide demonstrates where exactly the Minamata disease relief measure resources were located.  The semi-urban Minamata city area was affected the most, and to date there are 2,265 certified Minamata disease victims from this area. The demographics most affected by the disease were industrial workers who worked at the Chisso plant, local community members that lived near the plant, and by the Minamata bay and Agano river basin , and the fisherman of those bodies of water. All came in contact with the water that had poisonous levels of methyl-mercury (Torrente, 2019). 

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Chronic Disease & Country Information: 2-4 slides 

The picture to the right is an aerial view of Minamata, Japan. 

The aerial picture includes where the Chisso factory is placed, in accordance with the semi-urban city (Torrente, 2019). 

Figure 4.  Minamata, Japan Aerial View, Adapted From, "Minamata Disease, Japan".  Torrente, D. (2019).  https://ejatlas.org/conflict/minamata-disease-japan 

The aerial view picture allows the audience to get a feel of how close knit this community must have been during the outbreak and continuation of Minamata disease. When symptoms began to arise such as out of the blue mental and physical symptoms such as ataxia, numbness in the hands and feet, and damaged hearing, vision, and speech; the entire community began to realize it was a not something to take lightly. The first case of Minamata disease was diagnosed in May of 1956 and 2,264 individuals would be diagnosed with the same disease soon after.  (Yorifuji and Tsuda, 2014). 

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Proposed Program/ Project 3-4 slides

Figure 5  Dredged Areas with sediments transferred to segregated  bay  area – source (Sakamoto et al., 2020) 

                                                                                                                                        Dredging of Contaminated Bottom Sediment  

                                                                                                                          Mercury-contaminated sludge treatment by                                                                                                                                dredging in Minamata Bay (Yoshinaga, 1995) 

                                                                     

                                                                                                                           Dredged material was  discharged  into the  I                                                                                                                       nto thereclamation area (Yoshinaga, 1995)

Note from Sakamoto, M., Itai, T., Marumoto, K., Marumoto, M., Kodamatani, H., Tomiyasu, T., Nagasaka,                                                                                                                       H., Mori, K., Poulain, A. J., Domingo, J. L., Horvat, M., & Matsuyama, A. (2020). Mercury speciation in                                                                                                                         preserved historical sludge: Potential risk from sludge contained within reclaimed land of Minamata Bay, Japan.                                                                                                                Environmental Research, 180, 108668. https://doi.org/10.1016/j.envres.2019.108668

Include detailed information about the type of program, how it will decrease or eliminate the disease, why it was chosen, etc.

7 bullet point minimum

Proposed Program/ Project 3-4 slides

                                                                                                 Figure 6  - The provisional regulatory standard for fish has been e                                                                                                                                   stablished, stipulating 0.4 ppm for total mercury and 0.3 

Restoration of the environment.                                           

 Fishing-Related Measures 

 Effluent control 

Restraint on intake of fish and shellfish 

  

Haawa Wasswa

Note from Minamata Disease The History and Measures - Chapter 4. (n.d.). Ministry of the Environment, Government of Japan.  https://www.env.go.jp/en/chemi/hs/minamata2002/ch4.html

Proposed Program/ Project

Water Pollution Control Law

Enacted in 1970

Several objectives to prevent repetition of mercury pollution.

Objectives Included

Prevention of further pollution of the water & surrounding environment by regulating the discharge of pollutants, including mercury, from industrial sources.

Promote conservation of the environment & protect the health of the people living in the affected areas

Proposed Program/ Project

Water Pollution Control Law Objectives Continued

Establish monitoring & enforcement mechanisms to ensure compliance with the regulations and to detect and respond to any violations.

Provide compensation & support to those affected by the pollution, including medical care & financial assistance.

Promote research & development to better understand the effects of mercury pollution & to develop new technologies to prevent & mitigate pollution.

Assessment 2-3 slides

Measure current total methylmercury levels.

The assessment that is going to be used will determine the most current mercury levels in the Minamata Bay water. 

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Assessment 2-3 slides 

Assessment 2-3 slides: The Aftermath of Minamata Disease Exposure on Surviving Residents

Present symptoms of an exposed individuals:

Numbness of hands: 86-39%

Walking impairment: 50-65%

Visual impairment: 21-30%

Present symptoms of a controlled group:

Numbness of hands: 3%

Walking impairment: 9%

Visual impairment: 1%

The most recent revisiting study that examined two groups from different regions between November 2004 and March 2016 that concluded in terms of gender and present symptoms between the exposed and the controlled groups.

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Exposed Group:

Total Minamata Disease exposure: 10,196

Men: 4,486

Women: 5,350

Controlled Group:

Total residents selected: 214

Men: 91

Women: 123

Evaluation 2-3 slides                  Strengths and Weaknesses.

Strengths

  Mercury toxicity and environmental health research.

  Epidemiology, toxicology, and social science partnership.

  Environmentalism and health advocacy.

  Minamata illness research and original data.

  Long-term illness tracking.

  International knowledge-sharing and cooperation.

Weaknesses

Limited primary outbreak data.

Self-reported statistics may be inaccurate or biased.

Socioeconomic differences and challenges meeting impacted populations' needs.

Resources and lag periods make longitudinal investigations difficult.

Few effective Minamata disease therapies.

Ethics in participant well-being and privacy.

Underreporting and difficulty estimating Minamata disease cases.

Evaluation 2-3 slides What can make it Better and Another Program

Improvements

Standardize data collecting for study comparability.

Promote worldwide Minamata disease research to include varied viewpoints and experiences.

Monitor mercury levels and cleanup actions throughout time.

Study disease transmission and long-term impact across generations.

Research Minamata illness treatments.

Address health inequalities and socioeconomic determinants of illness for equitable healthcare and resources.

Educate the people about Minamata's illness to empower and decrease stigma.

Brazil (Amazon) Mercury Monitoring Network

The study is conducted nationally, particularly in the Amazon region.

It investigates the mercury levels found in fish consumed by vulnerable populations.

It aims to examine the prevailing concerns regarding mercury contamination in the Amazon region.

Health, scientific, environmental, and community collaboration

The primary goals are Mercury levels, at-risk groups, and exposure reduction techniques.

Evaluation 2-3 slides

References

Areas with outbreak of Minamata disease [Map]. Minamata Disease Archives.  http://nimd.env.go.jp/archives/english/minamata_disease_in_depth/

Eto, K., Marumoto, M., & Takeya, M. (2010). The pathology of methylmercury poisoning (Minamata disease) the 50th anniversary of Japanese society of neuropathology. Neuropathology, 30(5), 471-479. https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1440-1789.2010.01119.x 

Jackson, A. C. (2018). Chronic neurological disease due to methylmercury poisoning. Canadian Journal of Neurological Sciences, 45(6), 620-623. https://www.cambridge.org/core/services/aop-cambridge-core/content/view/17E848523B37A91FACA87320B8EC2E8D/S0317167118003232a.pdf/chronic_neurological_disease_due_to_methylmercury_poisoning.pdf

Minamata Disease The History and Measures - Chapter 4. (n.d.). Ministry of the Environment, Government of Japan. https://www.env.go.jp/en/chemi/hs/minamata2002/ch4.html

Moraes Pinto, L. D. C., Dórea, J. G., Bernardi, J. V. E., & Gomes, L. F. (2019). Mapping the evolution of mercury (Hg) research in the Amazon (1991–2017): A scientometric analysis. International Journal of Environmental Research and Public Health, 16(7), 1111. https://www.mdpi.com/435618

O'Carroll, R. E., Masterton, G., Dougall, N., Ebmeier, K. P., & Goodwin, G. M. (1995). The neuropsychiatric sequelae of mercury poisoning: the Mad Hatter's disease revisited. The British Journal of Psychiatry, 167(1), 95-98.  https://www.researchgate.net/profile/Ronan-Ocarroll/publication/15646735_The_Neuropsychiatric_Sequelae_of_Mercury_Poisoning_The_Mad_Hatter's_Disease_Revisited/links/545c7e960cf2f1dbcbcb3039/The-Neuropsychiatric-Sequelae-of-Mercury-Poisoning-The-Mad-Hatters-Disease-Revisited.pdf

Pathway of Methylmercury from Factory to Human [Infographic]. Minamata Disease Archives.  http://nimd.env.go.jp/archives/english/minamata_disease_in_depth/

References

Sakamoto, M., Itai, T., Marumoto, K., Marumoto, M., Kodamatani, H., Tomiyasu, T., Nagasaka, H., Mori, K., Poulain, A. J., Domingo, J. L., Horvat, M., & Matsuyama, A. (2020). Mercury speciation in preserved historical sludge: Potential risk from sludge contained within reclaimed land of Minamata Bay, Japan. Environmental Research, 180, 108668.  https://doi.org/10.1016/j.envres.2019.108668

Takaoka, S., Fujino, T., Kawakami, Y., & Shigeoka, S. (2017, October 15). Prolonged and extensive health effects of methylmercury poisoning (Minamata disease) around the Shiranui sea. Shibboleth

Takizawa, Y. (1979). Minamata disease in Japan. Environmental toxicology and human health, 1, 325-366.  http://www.eolss.net/sample-Chapters/C09/E4-12-02-05.pdf

Torrente, D. (2019). Minamata Disease, Japan. Enviornmental Justice Atlas,  https://ejatlas.org/conflict/minamata-disease-japan 

 Authentication Request.  https://www-sciencedirect-com.ezproxy.uta.edu/science/article/pii/S0022510X17337760?via%3Dihub

 Yorifuji, T. and Tsuda, T. (2014). Minamata, Encyclopedia of Toxicology,   https://www.sciencedirect.com/referencework/9780123864550/encyclopedia-of-toxicology 

Yoshinaga, K. (1995, December 31). Mercury-contaminated sludge treatment by dredging in Minamata Bay. Mercury-contaminated sludge treatment by dredging in Minamata Bay (Conference) | OSTI.GOV.  https://www.osti.gov/biblio/419581 

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