| WBS ID | Task | Description |
| 1.0 | establishment of effective project management. | Is the process of developing the basics of the value driven project management |
| 1.1 | Target product profile (TPP) | the definition of the targeted patient population, the requested efficacy, safety and tolerability characteristics, and technical details |
| 1.2 | Decision tree analysis | illustrate R&D decision points, the probabilities of uncertain outcomes at each milestone, and potentially resulting decision options |
| 1.3 | The relevance of project risk structure | resolution of the risks per milestone |
| 1.4 | Financial project evaluation | use of NPV in the evaluation of the investments in the pharmaceutical industry |
| 2.0 | Development portfolio management | Qualitative and quantitative evaluation |
| 2.1 | Capacity management | Evaluation of the available and needed capacities |
| 2.2 | Portfolio management in different organisational systems | the portfolio management across the different departments and systems in an organization |
| 3.0 | Execution of value driven portfolio management | the actual execution of the value driven portfolio management |
| 3.1 | Evaluation of individual projects along a stage-gate decision process | Each individual project is evaluated along stage gate decision process |
| 3.2 | Project risk analysis | analyzing the threats of the various projects |
| 3.3 | Financial evaluation | evaluation of the fiancial requirements and metrics for the project |
| 4.0 | Control and monitoring | the processes after the value driven projects are implemented |
| 4.1 | Research portfolio evaluation | review all projects every 6-12 months. |
| 4.2 | Scoring | rating the projects according to the financial performance and other aspects |
| 4.3 | Portfolio risk evaluation | ensuring that the portfolio is balanced in terms of the risks and rewards |
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MILESTONE21.xlsx
