Course Project - Executive Summary

Ebola Bibliography

Jessica Seifert

Rasmussen College

March 4, 2018

Cenciarelli, O., Pietropaoli, S., Malizia, A., Carestia, M., D’Amico, F., Sassolini, A., Gaudio, P.

(2015). Ebola Virus Disease 2013-2014 Outbreak in West Africa: An Analysis of the Epidemic Spread and Response. International Journal of Microbiology, 2015, 1-12. doi:10.1155/2015/769121

The article focuses on the Ebola epidemic in West Africa. According to Cenciarelli et al., the Ebola Virus is characterized by a high fatality rate and is categorized as one of the most viral diseases globally. There are different Ebola viruses, and they adopted the names of the nations where they got discovered. Some include the Tai Forest Virus, Reston virus, Sudan Virus as well as Zaire virus among others. The virus is highly infectious. The article will be useful in the writing of the research paper. Firstly, it provides information on the etiology of Ebola, its symptoms and also the preventive measures. Secondly, it also offers statistical information on the outbreak of Ebola in West African countries. This information will play a critical role in providing a backup to the theoretical knowledge on epidemics (Cenciarelli et al., 2015).

Gupta, M., Spiropoulou, C., & Rollin, P. E. (2013). Ebola virus infection of human PBMCs causes the massive death of macrophages, CD4 and CD8 T cell subpopulations in vitro. Virology, 364(1), 45-54.

According to Gupta et al., Ebola affects the immunity of an individual making it irresponsive. Inflammation in the affected individuals also characterizes it. The virus leads to the death of macrophages, destruction of CD4 and CD8 T cells. This concept got arrived at after a comparative study. The information found in this article is paramount. To begin with, it contributes to the general of the topic. Secondly, it provides a comparative study that helps in the comprehension of how the virus destroys essential cells in the body hence its high rate of fatality (Gupta, Spiropoulou, & Rollin, 2013).

Wahl-Jensen, V. M., Afanasieva, T. A., Seebach, J., Ströher, U., Feldmann, H., & Schnittler, H.

J. (2016). Effects of Ebola virus glycoproteins on endothelial cell activation and barrier function. Journal of Virology, 79(16), 10442-10450.

The authors of the article begin by acknowledging the high mortality rate (89%) which gets linked to the virus. The virus destroys the endothelial cells. According to the report, there was a significant impairment of the endothelial cells by the Ebola virus. There was also an alteration of the barrier function. The information presented in this article will be of great significance in the composition of the research paper on Ebola. Firstly, it provides case studies that were carried out and can get relied on when providing explanations on the destructive impact of this virus on body cells. Besides, it also gives information that enhances the general understanding of the topic (Wahl-Jensen, Afanasieva, Seebach, Ströher, Feldmann, & Schnittler, 2016).

Outline

I. INTRODUCTION-THESIS STATEMENT

Ebola is one of the short time impact diseases whose fatality is high in both humans and animals.

II. DEFINITION

It is defined one of the viral illness in Human beings whose transmission is from animals to human beings.

III. CAUSES OF EBOLA

It is a viral disease and therefore caused by a virus. The virus is found in the Ebolavirus as well as Filoviridae family.

IV. SYMPTOMS

There are many symptoms of Ebola. Common ones include;

a. Headache

b. Fever

c. Diarrhea

d. Joint pains

e. Breathing difficulty etc.

V. RESEARCH AND OUTBREAKS

Many types of studies have been done on Ebola to establish its origin. The researchers get closely linked to the identification of outbreaks. Some investigations indicate that West African country such a Liberia and the Democratic Republic of Congo have had the latest outbreaks.

VI. PREVENTION MEASURES AND TREATMENT

No single form of therapy has gotten identified for the virus. However, supportive and intensive care for the patients can be helpful. The World Health Organization has yet licensed vaccines that could be used shortly to treat Ebola.

Some preventive measures include;

a. Using long sleeves preventive clothing

b. Patient isolation

c. Equipment sterilization among others.

VII. CONCLUSION

Ebola is one of the dangerous viral infections with high fatality rates. Once symptoms have been noted, the preventive measures ought to be adopted to prevent further spread.