1492 Columbus sails west to the Bahamas
1495 Syphilis epidemic begins to spread in the middle east and Europe
1498 Michelangelo paints St. Peter's
1501 Card games gain popularity in Europe
1509 Henry VIII, King of England; Earthquake destroys Constaninople
1515 Francis I, King of France
1513 Sistine Chapel complete
1517 coffee introduced in europe;
Reformation begins with Luther's "95 Theses"
1520 Suleiman I sultan of Turkey (Ottoman Empire, to 1566)
1521 Cortes defeats the Aztecs; Silk made in France for the first time
Diet of Worms; Pope Leo X excommunicates Martin Luther
1522 Magellan's Expedition circumnavigates the world
1526 Mughal Empire in India (to mid 1700s)
1530 exchange at Antwerp founded; Bottle cork invented
1531 Halley's comet
1533 Pizarro begins conquest of the Incas (to 1565)
1547 Miquel de Cervantes (to 1616)
1558 Elizabeth I Queen of England; Ferdinand I Holy Roman Emperor
1560 Condom inveneted in Italy (linen)
1564 Galileo Galilei (to 1642)
1567 Portuguese settle at Rio de Janerio (Brazil)
1528 Grenade invented in France
1588 English defeat of the Spanish Armada
1589 Henry of Navarre first Burbon king of France
1590 Hideyoshi unifies Japan; Shakespeare's plays first produced
Microscope (Netherlands) and Telescope (Italy) invented
1591 Songhai Empire destroyed by mercenaries fighting for Morocco
1594 Galileo's golden rule
1596 Sir John Harington designs the first "water closet"
Rene Descartes (to 1650)
1600 Founding of the British East India Co. (Dutch 1602, French 1604)
Tokugawa period begins in Japan, capital moved to Edo (Tokyo)
1609 tea introduced in Europe
1610 Henry Hudson explores north american waterways;
Louis XIII King of France;
Flintlock firing mechanism invented (France)
1619 1st colonial assembly Jamestown
1620 Pilgrims establish the New Plymouth colony (Massachusetts)
1623 calculator/adding Machine invented in Germany
1625 Charles I King of England
1630 bucanneers setttle Tartuga
1642 English civil wars
1644 Manchu dynasty in china (to 1912)
1649 Commonwealth in England (Oliver Cromwell)
1652 Capetown founded by the Dutch (South Africa)
1654 Louis XIV begins rule of King of France
1658 Leopold I Holy Roman Emperor
1661 Charles II King of England
1665 great plague of London
1666 great fire of London
1670 French monk Dom Perignon invents champagne
1676 " Declaration of the People of Virgina";
Sikh uprising in India
1680 Pueblo tribes drive Spanish missionaries out of Rio Grande Valley
Dodo extinct
1685 Chinese ports open to foreign trade
1689 Peter the Great Czar of Russia
1698 Steam pump invented (England)