gero 302 assignment

Annotated bibliography

Reference

Alzheimer’s, A. (2015). 2015 Alzheimer's disease facts and figures. Alzheimer's & dementia: the journal of the Alzheimer's Association, 11(3), 332.

The above report focuses on public health and the impacts the Alzheimer’s diseases (AD), it includes all the incidences and the prevailing mortality rates. It also covers cost incurred for caring and also the effect felt by the care givers and the society at large. This report focuses the issues encountered by the health care providers as they try to disclose the AD diagnosis to the patients as well as the care givers. Approximately 5.29 million Americans are diagnosed with AD; 200,000 have an average of below 65 years and 5.1 million are about 65 years. In the U.S. someone will develop AD after every 67 seconds. The expectations are that by 2050, AD will develop after every 33 seconds which will result to nearly a million cases per year. Ad is the sixth leading cause of death in the U.S. disclosure of the AD is usually too hard for the health specialists. Improvement of the disclosure process is supposed to be improved. This article will be useful as I develop my paper since it is much elaborate on the issue of the AD and also gives the statistics on the rate of the infection and so it verses me with the required information to develop an elaborate paper.

Bird, T. D. (2015). Alzheimer disease overview

According to the above reference, the characteristic of AD is Dementia which typically starts with a subtle as well as memory failure which in turn become incapacitating. There are also other r common findings which include poor judgment, confusion, agitation, language disturbance as well as hallucinations. Sometimes seizures are experienced, increased muscle tones, incontinence, myoclonus and mutism also occurs. Death is caused by malnutrition, pneumonia and general inanition. The recommended clinic duration is usually between 8 to 10 years. As we note from the above reference, the disease is explained in details and this gives me the knowledge of the characteristics of the disease and also the characteristics. This is very important in my paper since it provides me with the best knowledge on the characteristics and the symptoms of the disease.

Kumar, A., & Singh, A. (2015). A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacological Reports, 67(2), 195-203.

According to Anil Kumar AD disease is known to be a neurodegenerative disorder that is multifarious and progressive. He further explains that this disease is the major cause of Dementia especially in the late adult life. According to pathology, AD is usually characterized by the intracellular tangle of neurofibrillary and also the deposits of the extracellular amyloidal proteins that bring about plaques of senile. The advancing study of pathogenesis has inspired the investigation of therapeutic study towards the pathophysiological events. The reference explains deeply about AD and also mentions the diseases major cause. The information provided is helpful in my paper since it gives details of the cause of AD.

Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., ... & Cooper, C. (2017). Dementia prevention, intervention, and care. The Lancet, 390(10113), 2673-2734.

In the paper above, Gill and his counterparts tackle the issue about the safety measures to be taken. They say that acting now on ways to prevent AD and intervene as well as exercising care to the infected can largely improve the living. Cases of death will be minimal due to the presence of a vast knowledge about the disease. The lives of people leaving with dementia and their families will improve and by so doing this will significantly bring a transformation to the future of the society. This reference gives the details on how we are supposed to handle the situation of people living with dementia. This knowledge is of much significance to my paper because as much as I will discuss the dementia disease, I will also need to talk about how to live with the infected.

Nelson, L., & Tabet, N. (2015). Slowing the progression of Alzheimer’s disease; what works?. Ageing research reviews, 23, 193-209.

In this reference, Lucy and Naji explain that Alzheimer’s disease is a disease associated with age and dementia progresses with the age and it is increasing worldwide. It typically affects the short term memory as it onsets. This illness which is devastating advances until it brings impaireness to all the aspects associated with cognitive and the non-cognitive domain too. Nowadays a lot of effort has been put in place a disease modifying treatment or medication but the most promising get faltered during the preclinical research. Because of that failure to get an effective medication, the all the efforts have been shifted to gaining insight on the preventive measures. The authors of this reference explain the efforts that are put in place in order to counter the problem of the increasing disease.

Robinson, L., Tang, E., & Taylor, J. P. (2015). Dementia: timely diagnosis and early intervention. Bmj, 350, h3029

Robinson, Tang and Taylor explain their efforts for searching for articles thro Medline, coochrane as well as the pub med and also did research of the available systematic reviews from 2006 all the way to 2014. They talked about pharmacologic treatment as well as the non-pharmacologic treatment. They further explain strategies/interventions and treatment. They also focus on systematic reviews and the Meta analysis and the high quality randomized trials based on control. The authors also include the expected figures of who will have dementia in the future. They further explain the cause of delayed diagnosis. Such information is of much help to me as I develop and advance in writing may paper which should be detailed.

Rosenberg, P. B., Nowrangi, M. A., & Lyketsos, C. G. (2015). Neuropsychiatric symptoms in Alzheimer's disease: what might be associated brain circuits?. Molecular aspects of medicine, 43, 25-37.

According to the above researchers, Neuropsychiatric symptoms (NPS) are usually very common in the AD disease in particular, apathy, agitation, delusions and depressions. All the brain networks or the circuits where these symptoms underlie are now trying to be understood. The growing neurochemical evidence together with imaging form a base to the understanding of the potential mechanisms of the Neuropsychiatric symptoms (NPS). The authors also offer review of the recent literature and even an hypotheses concerning networks or the circuit’s which underlie these NPS in particular the apathy, agitation and even the delusions. This informationis found in details as we continue analyzing the book. It gives a clear outline on NPS symptoms common in the AD.

Stokes, G. (2017). Challenging behavior in dementia: a person-centred approach. Routledge.

Graham stokes explains how he never intended to work in the field of dementia. He thought that this could be as a result of lack of ambition or due to poor judgment. He was attracted to neuropsychology and also to research on management of dementia. He says that all the people that spent time with those infected by dementia should be appreciated. He says that working with the people whose memories are failing should be appreciated. He further explains the need to manage the rapidly ensuing problem. The main purpose of his book is to rapidly communicate about the expanding knowledge of the psychology the Dementia disease. This information is good for my paper since it gets me to know more about the psychology of the disease.

Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C., Brodaty, H., ... & Fratiglioni, L. (2016). Defeating Alzheimer's disease and other dementias: a priority for European science and society. The Lancet Neurology, 15(5), 455-532.

Winblad and his team in this book explain that Alzheimer’s disease (AD) tops the list of causing Dementia. They further state that dementia increases with an increase in the age globally. This disease affects even the wealthier countries and the medical care cost is usually a burden since the numbers of Dementia infections increase overwhelmingly since almost everybody is living into old age. They explain the effort of the government and the policy makers as they make incentives that provide more resources to develop AD therapeutics. This shows that it is a national disaster and a threat to everyone.

Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan, L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis. Journal of affective disorders, 190, 264-271.

Finally Zhao and his team explain that (NPS) symptoms are progressively recognized as a common serious problem in the AD disease. They further say that the data provided on the prevalence of NPS in the people with AD do conflict with the meta- analysis that is aimed at to approximate the prevalence of the NPS. All the above information is necessary in the development of my paper since it will be much detailed and it will discuss and touch on every bit concerning the AD disease.