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GreenlightBiosciencesPresentationfromAndrew.pptx

Andrew Ramirez

Overview

Zarur and Cobb

Greenlight Bioscience

Vision

Impact investment

Four tenets of impact investing

First problem

SWOT

Choices

Recommendation

conclusion

Andrey J. Zarur Ph.D. CO-FOUNDER, PRESIDENT, & CEO

Born and raised in Mexico

Gained his Ph. D. at MIT

started his second company in 2002 BioProcessors Inc.

Became the managing director of Kodiak Ventures life sciences investment portfolio for 10 years

Founded Greenlight Biosciences in 2009 but wouldn’t leave Kodiak until 2012

Carole Cobb CHIEF OPERATING OFFICER

Carole Cobb has a masters in business administration in finance

She also has B.S. degrees chemical engineering, biochemistry and cell and molecular biology

Was the SVP of global supply at Genencor international and continued when acquired by Danisco

Joined Greenlight Biosciences in 2015 even though she meant to retire a few months earlier

Greenlight Biosciences

Founded in 2009

The concept was to take the “life” component out of cells but maintain the mechanics of the cell.

Over the initial 5 – 6 years and $24 dollars later the company would refine a process to develop “zombie cells”

The platform was complete but there was no application

Syngenta approached greenlight and wanted to use the platform to produce RNAi for agricultural use

As of 2016 Greenlight had proof of concept for the agricultural RNAi project and would need 1.5 – 2 years to finalize the process and another round of financing

Zarur’s Vision

Due to the utility of RNAi and Greenlights ability to produce the RNAi at a significantly lower cost than normal Zarur wanted to use the technology for life changing applications

After talking to a Princess Mabel Van Orenje, Zarur was convinced to try and use the technology to address malaria

On top of attempting to address malaria Zarur wanted to use the Technology for pesticide purposes in order to improve global food security

Impact investment

Mabel Van Orenje introduced impact investment to Zarur, a relatively new investment type that may allow Greenlight to acquire funding without sacrificing Zarur’s Vision

Impact investing constitutes investments that are intended to make positive and measurable social and environmental impact along with financial returns (GIIN, 2021)

Estimated to have over $110 Billion in assets under management in 2016 over double from the previous year

https://knowledge.insead.edu/strategy/maximising-outcomes-in-impact-investing-13636

Four tenets of impact investing

Intentionality – the investors intention must be to have a positive social or environmental impact

Investment return – the investment is expected to make a return on capital or at the very least a return of capital

Range of return expectations and asset classes – return expectations could be below market, risk adjusted market rates and could be across market classes

Impact Measurement – reporting of investments, financial as well as social and environmental performance, to show a measurable impact

Initial Problem

Projections showed that Greenlight would run out of financing in six months

Zarur wanted to utilize the technology to combat malaria and other pests that plague rural farms

If Zarur and Cobb wen the traditional VC investor route they knew they would not be able to pursue the malaria/pest issue

Impact investing showed promise as an opportunity for Zarur and Cobb to gain financing and still go after this vision

SWOT

Strengths

Proof of concept for the RNAi pesticide

Significantly lower production cost

Strong leadership under Cobb and Zarur

Innovative proprietary platform of zombie cells

High impact vision (now)

weakness

Reluctance of board to seek impact investment

Constantly changing vision (early on)

Early-stage company

Currently not profitable

No fully developed product

Opportunities

Venture Capital Investments

Cobb and Zarur have plenty of experience dealing with VC investors

Would set Greenlight on a more profitable path

Larger amounts of funds available to solicit to

Impact investments

Could provide investments without affecting the overall vision of Zarur

Impacts the world while still allowing for financial return

A lot of opportunities available through the Princes Mabel Van Orenje

Pursuing impact investment

Zarur and Cobb were connected to many potential impact investors through the Mabel Van Orenje

Met wit the Innovative Vector Control Consortium and developed a very comprehensive outline of Greenlight and their capabilities

Zarur and Cobb met with two major Foundations that dealt with impact investments

Foundation “A” showed interest in Greenlights capabilities but overall did not feel that the company was far enough along to invest into. “too much risk and in a vision stage”

Foundation “B” agricultural investment head had little to no background in agriculture and said they only invest in “tried and true” methods (not really impact investing in my opinion) so she rejected them

After four months of searching for funds via impact investments Zarur and Cobb had nothing

Threat

After four months Cobb and Zarur have nothing to show for their efforts and only have two months left to secure funds

Cobb and Zarur risk losing the company to Agilent if they can't secure funding in time

VC investments would most likely push Zarur’s vision to the wayside in favor of more profitable applications

The Big Problem

Greenlight is running out of money

They have been rejected by two major foundations but on the other side of the coin they have gained even more connections through the foundations

After four months of trying to get funding through impact investing, they still have nothing

Choices – What funding should they pursue now?

Impact investment

Continue pursuing impact investments over the next two months

Haven't received any funding so far

Have made many network connections and had a lot of support

Venture Capital Investment

Cobb and Zarur have a lot of experience in this arena

Would set the company on a profit driven path (initially)

Zarur’s Vision would be pushed back significantly

Impact investing route

Low chance of success based on the previous four months

Greenlight holds to much risk and not enough maturity as well as not having an actual product for impact investors to want to throw their hat in

Run the risk of not making raising enough capital and this could end in Agilent acquiring Greenlight

If it works out though Zarur will be able to carry out his vision of malaria eradication

Venture Capital Route

Cobb and Zarur have a lot of experience with VC investors and have an extensive network to tap into

VC investors are willing to accept more risk if the reward is large enough

This would point Greenlight toward less impactful but more profitable targets

More than 80% of venture capital investments goes into adolescent stage companies according to the Harvard Business review

Zarur would not be able to combat malaria for a long time

Recommendation

Venture Capital route

The success chance of securing financing in this route for Zarur and Cobb is pretty good

It would allow for Greenlight to continue and become profitable

They would have the Support of the Board and management

Does not completely eliminate the possibility of Zarur eventually being able to combat malaria

Would help focus the company on a goal (the most profitable pest)

Conclusion

Greenlight Biosciences developed an innovative “Zombie Cell” platform to create biological products cheaper

Zarur’s Vision was to use the platform to create RNAi products to combat malaria

The company was running out of money so Zarur and Cobb needed to secure funds they tried to get impact investments

Failing to receive any funds via impact investments Zarur and Cobb had to make a choice on whether to continue their path or return to VC investors for funds

I recommend returning to VC investors to keep the company going and to pursue the malaria products later

References

GIIN. (2021). WHAT YOU NEED TO KNOW ABOUT IMPACT INVESTING. Retrieved from Global Impact Investing Network: https://thegiin.org/impact-investing/need-to-know/

Greenlight Biosciences. (2021). About Us`. Retrieved from Greenlight Biosciences: https://www.greenlightbiosciences.com/about-us/

Greenlight Biosciences. (2021). Andrey J. Zarur, Ph.D. Retrieved from Greenlight Biosciences: https://www.greenlightbiosciences.com/team/andrey-j-zarur/

Marshall, M. P. (2020, June 11). 15 MINUTES WITH… ANDREY ZARUR OF GREENLIGHT BIOSCIENCES. Retrieved from Global AgInvesting: https://www.globalaginvesting.com/15-minutes-andrey-zarur-greenlight-biosciences/

Michael Chu, A. L. (2018). Greenlight BioSciences: in search of Impact Investment. Harvard: Harvard Business School.

Singh, J. (2020, March 26). Maximising Outcomes in impact investing. Retrieved from Insead knowledge: https://knowledge.insead.edu/strategy/maximising-outcomes-in-impact-investing-13636

Synbiobeta. (2021). Carole Cobb. Retrieved from Synbiobeta: https://2018.synbiobeta.com/carole-cobb/

Zider, B. (1998, November). How Venture Capital Works. Retrieved from Harvard Business Review: https://hbr.org/1998/11/how-venture-capital-works